No abstract available.

No abstract available.
Ovotesticular Disorders of Sex Development*

BACKGROUND: The government staffs studied in this research has been easily exposed to excessive job stress, which can lead to a variety of psychosocial problems and poor quality of life. In this study, we examined the effect of the self reflection meditation program on the psychosocial health and stress responses of government staffs, to suggest the intervention program improving psychosocial health and quality of life in government staffs.METHODS: In this study, we measured the conditions of 36 local government staffs based on self reflection scale, psychosocial health and stress score before and after implementing the short-term intensive meditation program.RESULTS: The results showed that there were significant increase in social role performance and self confidence(p=.003), general health and vitality(p=.019) and significant decrease in stress(p=.010). This change was prominently showed in administrative officer and depression and anxiety(p=.034) also significantly decreased after program.CONCLUSION: Self reflection meditation program was effective in improving the psychosocial health and physical health of government staffs. Therefore, self reflection meditation program could be proposed as program for stress management and promotion of quality of life in government staff.
Depression ; Local Government ; Meditation ; Quality of Life

No abstract available.
Diagnosis*

The coronavirus disease-2019 (COVID-19) pandemic has significantly impacted adolescent health, highlighting the need for effective health promotion strategies. This qualitative study analyzed adolescent health concerns during the pandemic and explored management strategies through focus group interviews (FGIs).FGIs were conducted on November 23 and 25, 2023, with six secondary school nutrition teachers, six educational supervisors, and six adolescent students. Semi-structured questions were used to explore five key domains: health behaviors, factors contributing to health problems, social support, perceived health beliefs, and health education. The FGI recordings were transcribed, and Braun and Clarke’s (2006) thematic analysis method was applied to classify and categorize the data. To ensure the reliability and validity of the study, all processes were meticulously documented, and member checking and triangulation were conducted. The analysis revealed that adolescents faced reduced physical activity, irregular eating habits, school lunch disruptions, social isolation, worsening obesity, mental health challenges, and decreased engagement in health-promoting behaviors. Nutrition teachers and educational supervisors emphasized the importance of the food environment in schools and policy support, whereas adolescent students. highlighted motivation and accessibility as the key factors for adopting healthy behaviors. Based on these findings, strengthening social support, expanding health education, and establishing a national support system are essential for improving adolescent health. This study has implications for policy and education to address adolescent health challenges during a pandemic and serves as a foundation for future health promotion strategies.

The coronavirus disease-2019 (COVID-19) pandemic has significantly impacted adolescent health, highlighting the need for effective health promotion strategies. This qualitative study analyzed adolescent health concerns during the pandemic and explored management strategies through focus group interviews (FGIs).FGIs were conducted on November 23 and 25, 2023, with six secondary school nutrition teachers, six educational supervisors, and six adolescent students. Semi-structured questions were used to explore five key domains: health behaviors, factors contributing to health problems, social support, perceived health beliefs, and health education. The FGI recordings were transcribed, and Braun and Clarke’s (2006) thematic analysis method was applied to classify and categorize the data. To ensure the reliability and validity of the study, all processes were meticulously documented, and member checking and triangulation were conducted. The analysis revealed that adolescents faced reduced physical activity, irregular eating habits, school lunch disruptions, social isolation, worsening obesity, mental health challenges, and decreased engagement in health-promoting behaviors. Nutrition teachers and educational supervisors emphasized the importance of the food environment in schools and policy support, whereas adolescent students. highlighted motivation and accessibility as the key factors for adopting healthy behaviors. Based on these findings, strengthening social support, expanding health education, and establishing a national support system are essential for improving adolescent health. This study has implications for policy and education to address adolescent health challenges during a pandemic and serves as a foundation for future health promotion strategies.

The coronavirus disease-2019 (COVID-19) pandemic has significantly impacted adolescent health, highlighting the need for effective health promotion strategies. This qualitative study analyzed adolescent health concerns during the pandemic and explored management strategies through focus group interviews (FGIs).FGIs were conducted on November 23 and 25, 2023, with six secondary school nutrition teachers, six educational supervisors, and six adolescent students. Semi-structured questions were used to explore five key domains: health behaviors, factors contributing to health problems, social support, perceived health beliefs, and health education. The FGI recordings were transcribed, and Braun and Clarke’s (2006) thematic analysis method was applied to classify and categorize the data. To ensure the reliability and validity of the study, all processes were meticulously documented, and member checking and triangulation were conducted. The analysis revealed that adolescents faced reduced physical activity, irregular eating habits, school lunch disruptions, social isolation, worsening obesity, mental health challenges, and decreased engagement in health-promoting behaviors. Nutrition teachers and educational supervisors emphasized the importance of the food environment in schools and policy support, whereas adolescent students. highlighted motivation and accessibility as the key factors for adopting healthy behaviors. Based on these findings, strengthening social support, expanding health education, and establishing a national support system are essential for improving adolescent health. This study has implications for policy and education to address adolescent health challenges during a pandemic and serves as a foundation for future health promotion strategies.

Many ocular findings have been shown in patients with chronic renal failure. There has been no systematic study on ocular manifestations in patients with chronic renal failure. The medical records of 349 patients with chronic renal failure, who were referred to ohthalmologic department, were reviewed. Of 349 patients, 109 were renal transplanted patients, 118 were hemodialysis, and 122 were CAPD. Sixty-five % were male, 35% were female, and their mean age was 42 years old. For renal transplanted patients, 47% had a visual acuity of 1.0 or better, while 6% had worse than finger counting. Nineteen % and 15% of hemodialysis, and 19% and 24% of CAPD patients had a visual acuity of 1.0 or better and worse than finger counting, respectively. Hypertension was the most common associated systemic disease. Primary causes of renal failure were chronic glomerulonephritis(44.4%), diabetic nephropathy(17.2%), hypertensive nephropathy(4.6%), and CRF NOS(29.5%). Hypertensive retinopathy(45.6%) was the most common ocular manifestation of all patients with renal failure. Others were cataract, diabetic retinopathy, ischemic optic neuropathy and retinal detachment. These results suggest that ocular complications are common in patients with chronic renal failure and therefore, close follow up has to be performed after renal transplantation and during dialysis.
Adult ; Cataract ; Diabetic Retinopathy ; Dialysis ; Female ; Fingers ; Follow-Up Studies ; Humans ; Hypertension ; Hypertensive Retinopathy ; Kidney Failure, Chronic* ; Kidney Transplantation ; Male ; Medical Records ; Optic Neuropathy, Ischemic ; Peritoneal Dialysis, Continuous Ambulatory ; Renal Dialysis ; Renal Insufficiency ; Retinal Detachment ; Visual Acuity

Hepatoblastoma is a primary embryonic liver tumor usually found in children. It extremely rarely occurs in adults. We report a case of hepatoblastoma in a 56 year old man with chronic hepatitis B of 10years duration. Laboratory investigation of the patient on admission showed a marked elevation of alpha-fetoprotein in serum. Ultrasonography and Computerized tomography scan revealed a primary tumor, 6x7cm in size, in the right lobe. The tumor removed by a right lobectomy. Complete removal of the tumor is the treatment which is potentially curative provided that lesion is confined within the liver capsule. The literature revealed and a case of this tumor reviewed.
Adult* ; alpha-Fetoproteins ; Child ; Hepatitis B, Chronic ; Hepatoblastoma* ; Humans ; Liver ; Middle Aged ; Ultrasonography

Preservation of peritoneal membrane function is important in the success of long-term peritoneal dialysis (PD). During PD, human peritoneal mesothelial cells (HPMC) are continuously exposed to unphysiological peritoneal dialysis solution(PDS) charaterized by high glucose and lactate concentrations, low pH, and hyperosmolality. Since few studies have examined the effects of lactate and pH on HPMC biology, the present study investigated the effects of lactate and pH on the viability and proliferation of cultured HPMC and on the production of TGF-beta1, a fibrogenic cytokine, and fibronectin by cultured HPMC. HPMC were obtained from the omental tissue of pregnant women who were undergoing Cesarean section. Cells at confluence were utilized to determine the viability(LDH release), proliferation([3H]-thymidine incorporation), and the production of fibronectin and TGF-beta1(ELISA) after synchronizing the cell growth by incubating with serum free media for 24 hours. After exposure to the media containing lactate and pH, LDH release increased in dose- and time-dependent manner. Both 1.5% and 4.25% commercial PD solutions were cytotoxic and induced more than 80% LDH release within 24 hours. LDH release decreased with increasing dilution of commercial peritoneal dialysate, but there was no significant difference in LDH release between 1.5% and 4.25% PDS. LDH release increased in response to pH 5.5. Thymidine incorporation assay revealed that lactate and low pH significantly inhibited proliferation of HPMC. ELISA revealed that exposure of HPMC to lactate and low pH decreased fibronectin protein synthesis, when compared to cell exposed to bicarbonate containing M199 media. Our results clearly show that lactate and low pH lead to dose- and time-dependent cell death and reduce proliferation of cultured HPMC. Lactate and low pH per se appear to decrease fibronectin production by HPMC but may set a stage for other factors to promote progressive fibrosis during the healing stage in long-term PD.
Biology ; Cell Death ; Cesarean Section ; Culture Media, Serum-Free ; Enzyme-Linked Immunosorbent Assay ; Female ; Fibronectins ; Fibrosis ; Glucose ; Humans* ; Hydrogen-Ion Concentration* ; Lactic Acid* ; Membranes ; Peritoneal Dialysis ; Pregnancy ; Pregnant Women ; Thymidine ; Transforming Growth Factor beta1