1.The Effect of Mindfulness-Based Cognitive Therapy on Psychiatric Staff.
Bum Seung KANG ; Hey Jung YANG ; Min Ha HONG ; Hyun Soo KIM ; Hoo Rim SONG ; Young Jong KIM ; Woo Jung KIM
Korean Journal of Psychosomatic Medicine 2017;25(1):12-18
OBJECTIVES: Psychiatric staffs may experience excessive work stress, burnout, and reduced job satisfaction in clinical settings. This can increase chances of diminishing their overall working efficiency or having difficulty managing their own mental health. The purpose of this study was to investigate the effect of group mindfulness- based cognitive therapy(MBCT) on job stress, burnout, self-efficacy, resilience, and job satisfaction. METHODS: Twenty eight psychiatric staffs who agreed to participate in the study were included. Self-report questionnaires were used to measure job stress, burnout, resilience, self-efficacy, and job satisfaction. To examine the effects of group MBCT, the scores were compared before and after MBCT. RESULTS: Work stress and burnout scale scores were significantly decreased after group MBCT. Resilience, job satisfaction, and self-efficacy scale scores were significantly increased after group MBCT. CONCLUSIONS: In the current study, group MBCT for psychiatric staffs helped to reduce their work stress and burnout, and, as well, helped to improve resilience, self-efficacy, and job satisfaction. This suggests that, in mental health treatment settings, psychiatric staffs can improve their mental health through group MBCT. Improving mental health of psychiatric staff may also have a positive impact on their patients.
Cognitive Therapy*
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Humans
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Job Satisfaction
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Mental Health
2.Urinary transglutaminase 2 as a potent biomarker to predict interstitial fibrosis and tubular atrophy of kidney allograft during early posttransplant period in deceased donor kidney transplantation
Jee Yeon KIM ; Yu Mee WEE ; Monica Young CHOI ; Hey Rim JUNG ; Ji Yoon CHOI ; Hyun Wook KWON ; Joo Hee JUNG ; Yong Mee CHO ; Heounjeong GO ; Minkyu HAN ; Young Hoon KIM ; Duck Jong HAN ; Sung SHIN
Annals of Surgical Treatment and Research 2019;97(1):27-35
PURPOSE: Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. We tested whether quantification of urinary TG2 may represent a noninvasive method to estimate the severity of kidney allograft fibrosis. METHODS: We prospectively collected urine specimens from 18 deceased donor kidney transplant recipients at 1-day, 7-day, 1-month, 3-month, and 6-month posttransplant. In addition, kidney allograft tissue specimens at 0-day and 6-month posttransplant were sampled to analyze the correlation of urinary TG2 and kidney allograft fibrosis. RESULTS: Thirteen recipients had increased interstitial fibrosis and tubular atrophy (IFTA) scores at the 6-month protocol biopsy (IFTA group). The mean level of urinary TG2 in the IFTA group was higher compared to that of 5 other recipients without IFTA (no IFTA group). Conversely, the mean level of urinary syndecan-4 in the IFTA group was lower than levels in patients without IFTA. In the IFTA group, double immunofluorescent staining revealed that TG2 intensity was significantly upregulated and colocalizations of TG2/heparin sulfate proteoglycan and nuclear syndecan-4 were prominent, usually around tubular structures. CONCLUSION: Urinary TG2 in early posttransplant periods is a potent biomarker for kidney allograft inflammation or fibrosis.
Allografts
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Atrophy
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Biomarkers
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Biopsy
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Extracellular Matrix
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Fibrosis
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Humans
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Inflammation
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Kidney Transplantation
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Kidney
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Methods
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Prospective Studies
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Proteoglycans
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Syndecan-4
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Tissue Donors
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Transplant Recipients