1.Decompressive Craniectomy for Acute Cerebral Infarction.
Heung Sun LEE ; Won Han SHIN ; Soon Kwan CHOI ; Bark Jang BYUN ; In Soo LEE
Journal of Korean Neurosurgical Society 1991;20(10-11):854-859
We present a series of 10 Patients(Seven men and three women with an average age of 53 years) who underwent decompressive craniectomy for treatment to massive brain swelling following acute cerebral infarction. Clinical signs of cerebral herniation(anisocoria or fixed and dilated pupil, and/or hemiplegia with decerebrate righidity) were present in all patients. Computed tomography and magnetic resonance imaging showed the mass effect by cerebral edema through midline shift. All patients were treated with an extensive craniectomy and duroplasty. Among them, one recovered without neurological deficit, three were moderately disabled but functionally dependent, three remained in a persistent vegetative state and three died within 9 days after surgery(good recovery=1, moderate disability=3, persistent vegetative state=3, death=3). The results suggest that decompressive craniectomy can be an useful lifesaving procedure for massive cerebral edema following widespread hemispheric infarction.
Brain Edema
;
Cerebral Infarction*
;
Decompressive Craniectomy*
;
Female
;
Hemiplegia
;
Humans
;
Infarction
;
Magnetic Resonance Imaging
;
Male
;
Persistent Vegetative State
;
Prognosis
;
Pupil
2.Correlation between distribution of eosinophil cationic protein and nasal hyperreactivity in perennial allergic rhinitis.
Heung Man LEE ; Chung Sic CHOI ; Geun JUNG ; Sang Hak LEE ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):283-291
No abstract available.
Eosinophil Cationic Protein*
;
Eosinophils*
;
Rhinitis*
3.Effects of intranasal applications of capsaicin in patients with nonallergic eosinophilic nasal hyperreactivity.
Man Soo KIM ; Jong Tae YOON ; Sang Hag LEE ; Heung Man LEE ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):274-282
No abstract available.
Capsaicin*
;
Eosinophils*
;
Humans
4.Efficacy of capsaicin sensitive nerve on goblet cells and submucosal glands in rats.
Sang Hag LEE ; Heung Man LEE ; Keun JUNG ; Chung Sik CHOI ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):264-273
No abstract available.
Animals
;
Capsaicin*
;
Goblet Cells*
;
Rats*
5.A Hemodynamic Study of Isolated Congenital Pulmonary Stenosis.
Won Heum SHIM ; Sung Soon KIM ; Woong Ku LEE ; Hong Do CHA ; Heung Jai CHOI
Korean Circulation Journal 1977;7(2):49-60
Isolated pulmonary stenosis, a relatively common congenital anomaly that accounts for about 10 percent of all congenital heart disease, is characterized by stenosis of pulmonary valve itself, infundibulum or both of them. Since cardiac catherterization was applied to man by Cournand and Ranges, pulmonary stenosis had been easily diagnosed and many clinical studies had been investigated. It has a wide clinical spectrum depending on the degree of stenosis. The electrocardiogram, phonocardiogram and chest X-ray have proved useful in estimating the severity of hemodynamic facotrs in individual cases. This series comprises 47 cases in whom the clinical diagnosis of isolated pulmonary stenosis was confirmed by right heart catheterization with cardiac cineangiography at Severance Hospital, Yonsei University. An attempt was made to correlate the electrocardiographic, phonocardiographic, chest X-ray findings, and types of stenosis with the hemodynamic data in these cases. 1. Of 47 patients, 33 were male and 14 female. Their ages ranged from 2 to 42 years: the mean age was 19.1 years. 2. The incidence was 5.9 percent of all 797 catheterized congenital heart disease cases. The pulmonary valvular stenosis was 30 (68.3%), infundibular 7 (14.6%) and combined 10 (21.6%) cases. 3. The correlation between electrocardiogram and hemodynamic data were as follows. i) The regression equation between right ventricular sysytolic pressure (RVSP) and height of R wave in V1 lead (RV1) was RVSP=3.32 RV1+48.2: its correlation coefficient was 0.818 and it was very significant (p=0.000). ii) The higher the RVSP, the more the frontal axis of QRS complex shifted to the right side (r=0.55. p=0.001). iii) The RVSP of the groups with positive ECG findings such as p-pulmonale, right ventricular hypertrophy or right ventricular strain were much higher than the RVSP of the groups without such findings (p=0.032.0.000, 0.000). iv) The group with RV1 higher than 20 mm showed much more elevated mean of RVSP than the group with lower RV1 (p=0.000). v) The groups with the above mentioned positive ECG findings showed good correlation with the severity of RVSP which was arbitrarily classified as 49 or less, 50~100, and 100 mmHg or more (chi-square=8.96, 26.69, 19.06; p=0.011, 0.000, 0.000). 4. The group with late occurrence of the maximum intensity of the ejection systolic murmur showed higher mean of RVSP than the group with early peak of the murmur (p=0.014). 5. The means of RVSP of the groups with chest X-ray findings such as decreased pulmonary vascularity, were much higher than the means of RVSP of the groups without such findings (p=0.000, 0.005, 0.015). The groups with above mentioned positive chest X-ray findings showed good corelations with the severity of RVSP which was classified as above limits (chi-square=7.55, 10.94, 13.36; p=0.022, 0.004, 0.001). 6. Combined pulmonary valvular and infundibular stenosis showed more severe systolic pressure gradient and higher mean of RVSP than the isolated types (p=0.000).
Axis, Cervical Vertebra
;
Blood Pressure
;
Cardiac Catheterization
;
Cardiac Catheters
;
Catheters
;
Cineangiography
;
Constriction, Pathologic
;
Diagnosis
;
Electrocardiography
;
Female
;
Heart Defects, Congenital
;
Hemodynamics*
;
Humans
;
Hypertrophy, Right Ventricular
;
Incidence
;
Male
;
Pulmonary Valve
;
Pulmonary Valve Stenosis*
;
Systolic Murmurs
;
Thorax
6.Clinical Manifestation of Childhood Acute Leukemia with Bone Involvement.
Kyoung Eun JEONG ; Hee Jung LEE ; Kwang Soon SONG ; Heung Sik KIM ; Chin Moo KANG
Journal of the Korean Pediatric Society 2000;43(6):806-813
PURPOSE: Bone involvement is known to develop in 40-70Yo of pediatric acute leukemia. We aimed to analyze the clinical course and result of therapy in pediatric acute leukemia with bone involvement. METHODS: Twenty-seven patients diagnosed as pediatric acute leukemia at Dong San Medical Center from Jan. 1996 to Aug. 1998 were evaluated. According to bone X-ray and whole body bone scan, the patients were divided into two groups. RESULTS: Twenty-seven patients were enrolled in this study with 14 patients(52Yo) showing definite bone involvement on simple X-ray or bone scan. Mean age of patients with bone involvement was 5.5 years. Regarding the type of leukemia, 9 patients(64%) were acute lymphocytic leukemia. Ten patients(71%) out of 14 with bone involvement complained of bone pain at the involved bony site. Site of involvement was most frequent in the lower extremity. On simple X-ray, osteolytic lesion was found in 7 patients(50%), diffuse osteopenia in 2 patients(14%) and pathologic fracture in 2 patients(14%). In bone scan, radioactivity was increased in whole cases of patients with bone involvement. Thirteen patients(93%) were completely remitted by chemo-therapy, but, one AML patient died due to induction failure. CONCLUSION: Bone involvement occured in 52% of pediatric acute leukemia. Bone involvement was more frequent in male patients in the lower extremity, and osteolytic lesion was the most frequent finding on simple X-ray. There was no relevence between bone involvement and prognosis. Further study will be needed to evaluate long-term survival and prognosis. (J Korean Pediatr Soc 2000;43:806-813)
Bone Diseases, Metabolic
;
Fractures, Spontaneous
;
Humans
;
Leukemia*
;
Lower Extremity
;
Male
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Prognosis
;
Radioactivity
7.Immunohistochemical study on the turnover of the tongue epithelium using anti-BrdU antibody in normal mice.
Heung Man LEE ; Man Su KIM ; Geun CHOI ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):80-87
No abstract available.
Animals
;
Epithelium*
;
Mice*
;
Tongue*
8.Bechterew's phenomenon in human.
Sa Yong CHAE ; Heung Youp LEE ; Young Soon SEONG ; Byung Do SUH
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):898-902
No abstract available.
Humans*
9.Modification of labeling index of basal cells of tongue epithelium and renal toxicity of cis-diamminedichloroplatinum in mice by diethyldithiocarbamate.
Geon CHOI ; Man Su KIM ; Chong Tae YOON ; Heung Man LEE ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):877-883
No abstract available.
Animals
;
Cisplatin*
;
Ditiocarb*
;
Epithelium*
;
Mice*
;
Tongue*
10.Estrogen and progesterone receptors in juvenile nasopharyngeal angiofibromas.
Geon CHOI ; Seon Tae KIM ; Sung Won CHAE ; Heung Man LEE ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(6):1219-1224
No abstract available.
Angiofibroma*
;
Estrogens*
;
Progesterone*
;
Receptors, Progesterone*