Idiopathic midline destructive disease(IMDD) is a subgroup of midline granuloma syndrome, which is a clinical entity characterized by a relentless uilcer ation of the upper air way involving the nose, the palate, and the face, with a fatal outcorne. A 32 year-old male had symptoms of nasal obstruct.ion and rhinorrhea for about 4 months prior to visiting the hospital ad was referred to our Department for evaluation of a verely destruct.ive skin lesions on his face. The patient, revealed unique clinopatholcgic featurs compat with IMDD. These were : 1) prescence of locally destructive lesion which were restricted to the upper respiratory tract. 2) abscence of systemic disease durin the follow up peroid, 3) The histologic features consisted of acute and chronic inflarnmation with a variable dearel of necrosis on the examination of repeated biopsy specimens, 4) inabiliy to demonst rate an infectious causative organisms on repeated laboratory tests.
Adult ; Biopsy ; Follow-Up Studies ; Granuloma* ; Humans ; Male ; Necrosis ; Nose ; Palate ; Respiratory System ; Skin

No abstract available.
Down Syndrome* ; Leukemia, Megakaryoblastic, Acute*

No abstract available.
Magnetic Resonance Imaging* ; Tuberculosis, Spinal*

Perforation of maxillary sinus is a common complication of implant placement in posterior maxilla. The purpose of this study was to evaluate the prognosis of sinus perforated implants placed in partially edentulous maxillae. Eighteen sinus perforated implants in 15 patients were examined for cumulative survival rate, radiographic preoperative bone level, and radiographic marginal bone level change. Twenty-two non-perforated implants in the same patients served as control. The results were as follows; 1. There was no statistically significant difference in cumulative survival rate between sinus perforated implants and non-perforated implants (P>0.05). 2. There was no statistically significant difference in the marginal bone level between sinus perforated implants and non-perforated implants (P>0.05). 3. There was no statistically significant difference in cumulative survival rate according to the preoperative bone level (P>0.05). These results suggests that perforation of maxillary sinus may not affect implant success in posterior maxillae.
Humans ; Maxilla ; Maxillary Sinus ; Prognosis ; Retrospective Studies* ; Survival Rate*

The purpose of this study was to evaluate the influence of accessibility to dental cervices of maxillary molars upon plaque control level of these areas. Fifthy-seven dental students with healthy gingiae participated in this study. Maxillary dental casts were fabricated for each participants. Using the casts, cervical accessibility was measured at the mid-palatal point of maxillary first and second molars. Cervical accessibility was defined as the perpendicular distance from the entrance of gingival sulcus to the imaginary line between the most protruded points of palatal gingiva and tooth surface, and classified into degree I(< or =0.5mm), II(>0.5mm, < or =1.0mm), III(>1.0mm, < or =1.5mm), and IV(>1.5mm). Plaque score was recorded as the distance from crest of gingival margin to the most coronal extent of plaque. Measurements of plaque score were repeated 3 times at 1-week intervals. After the baseline measurements, the participants began to use unitufted brushes on randomly assigned right or left side. Two weeks later, a session of plaque score records identical to the baseline measurements was started. The maxillary second molars showed higher cervical accessibility than the first molars(p<0.01), but the plaque scores of maxillary second molars were also higher than those of first molars(p<0.01). For the maxillary first molars, correlation between accessibility and plaque score was statistically significant, but such correlation was not found for the second molars. Use of unitufted brushes decreased the plaque score(p<0.01). Correlation between accessibility and the degree of plaque score improvement was not found. These findings suggest that cervical accessibility may influence the amount of plaque, and use of adjunctive oral hygiene devices may be helpful in maintaining optimal oral hygiene level at the areas of low cervical accessibility.
Gingiva ; Humans ; Molar* ; Oral Hygiene ; Students, Dental ; Tooth

The purpose of this study was to evaluate the success rate of Korean implant systems. A total of 245 implants were placed in 112 patients using different implant systems from February 1988 until June 2002. Data on implant systems, implant positions, surface treatments, guided bone regeneration procedure, marginal bone levels, and states of surrounding gingiva were collected. A follow-up evaluations were done after 1 year and 2 year of loading. Clinical parameters such as probing depth was evaluated at the last follow-up. The marginal bone loss after 1 year of loading was measured on periapical radiographs. Clinical comparisons were performed to evaluate implants loss in relation to the implant systems, implant positions, surface treatments, and guided bone regeneration procedure. There was no clinical difference of success rate in implant systems, implant positions, and surface treatments. Mean marginal bone resorption from the time of loading to 1 year follow-up was 0.31mm in Korean implant systems and 0.41mm in other implant systems. The cumulative survival rate of Korean implant systems and other implant systems at the 2-year of loading was 95.6% and 97.3% respectively. From these results, it was concluded that Korean implant systems could be successfully used in clinical dentistry.
Bone Regeneration ; Bone Resorption ; Dentistry ; Follow-Up Studies ; Gingiva ; Humans ; Retrospective Studies* ; Survival Rate

The purpose of this study is to present the results of the clerkship evaluation by the students using questionnaire, to discuss the problems revealed in performing the evaluation, and to find out the ways to improve the evaluation. In 2000, the evaluation has been conducted by the Department of Radiology, Seoul National University College of Medicine. The questionnaires filled-up by 97 junior students who completed the clerkship schedule of 2 weeks were analyzed in this study. The questionnaire consisted of 28 structured items with 5-grade scale each, the contents of which included the amount and level of the overall clerkship course and those of 5 subtypes of the clerkship(self-learning, student conference, student seminar, on-site clerkship, and small group discussion with faculty). In small group discussion, enthusiasm of each faculty, delivery effect, and difficulty of the contents were also evaluated. As a result, the most items were assessed to be slightly better than average(3 or 4 point of 5 scale). It was found that the small group discussion was most favored, whereas the student seminar was least favored. Faculty activity was also scored to be better than average. There were no significant differences among all faculty activity. The limitation of this study is failure of assessing the validity and reliability of the student response. In order to improve the evaluation, we should consider following four subjects: First, all the items are carefully developed to enhance the validity and reliability of the evaluation. Second, students should be fully informed of the objects of the evaluation before it is carried out. Third, teaching support facilities for the faculty are needed. Finally, an organization which takes complete charge of the instruction evaluation must be established.
Appointments and Schedules ; Humans ; Reproducibility of Results ; Seoul ; Surveys and Questionnaires

The study was conducted to compare the side effects in myelography of the two non-ionic water-soluble contrastmedias, Iopamidol(Niopam) and Metrizamide(Amipaque). A total of 111 patients were examined, 64 with Iopamidol and47 with Metizamide. Side effects consisted of headache, nausea, vomiting, dizziness, urinary difficulty, muscularpain, seizure, neurobehavioral distrubance, neurologial sign change, vital sign change and etc. The common sideeffects were headache, nausea, vomiting and dizziness in order of frequency. Most of the side effcts were subsidedwithin 24 hours following meylography. Iopamidol myelography caused fewer and milder side effects than Metrizamidestudy. The side effects were more commonly observed in cervial, thoracic or total myelography than in lumbarmyelography with either lopamidol or Metrizamide. There was no significant correlation between incidence of theside effects and premedication with phenobarbital or valium injection before myelography and CSF sampling duringthe procedure.
Diazepam ; Dizziness ; Headache ; Humans ; Incidence ; Iopamidol ; Iothalamic Acid ; Metrizamide ; Myelography ; Nausea ; Phenobarbital ; Premedication ; Seizures ; Vital Signs ; Vomiting

No abstract available.
Carcinoma, Hepatocellular*

The success of an implant is determined by its integration into the tissue surrounding the biomaterial. Surface roughness is considered to influence the behavior of adherent cells. The aim of this in vitro study was to determine the effect of surface roughness on Saos-2 osteoblast-like cells. Titanium disks blasted with 75 micrometer aluminum oxide particles and machined titanium disks were prepared. Saos-2 were plated on the disks at a density of 50,000 cells per well in 48-well dishes. After 1 hour, 1 day, 6 days cell numbers were counted. One day, 6 days after plating, alkaline phosphatase(ALPase) activity was determined. Compared to experimental group, the number of cells was significantly higher on control group. The stimulatory effect of surface roughness on ALPase was more pronounced on the experimental group than on control group. These results demonstrate that surface roughness alters proliferation and differentiation of osteoblasts. The results also suggest that implant surface roughness may play a role in determining phenotypic expression of cells.
Aluminum Oxide ; Cell Count ; Osteoblasts* ; Titanium*