No abstract available.

No abstract available.
Panniculitis, Lupus Erythematosus*

No abstract available.
Nucleolus Organizer Region* ; Proliferating Cell Nuclear Antigen*

No abstract available.
Nucleolus Organizer Region* ; Proliferating Cell Nuclear Antigen*

We report a case of doxycycline-induced phototoxicity in a 62-years-old male. The patient, had erythematous macules and patches on sun-exposed areas. A Phototest revealed a marked decreased minimal erythemai. dose (MED) to UVA (MED(UNA)=-10J/cm2). Photopatch tests with 1%, 5% Doxycycline ointment were negative. An oral provocation test was performed, which showed a positive result with a decrease of MED to UVA (MED(UVA)= 20J/cm2). After the cessation of doxycycline, his skin lesioris were improved markedly with complete loss of photosensitivity.
Dermatitis, Phototoxic* ; Doxycycline ; Humans ; Male ; Skin

The simultaneous existence of intrauterine and extrauterine pregnancies is known as a heterotopic pregnancy. Spontaneous heterotopic pregnancy is a rare event although its incidence has increased since the recent development of treatment of infertile women with ovulation induction or in-vitro fertilization and embryo transfer(IVF-ET).The theoretical rate of this condition was estimated to be approximately 1 in 30,000 pregnancies. The early diagnosis of heterotopic pregnancy is very difficult . So there is a high maternal morbidity and fetal loss. We reported a IVP - ET patient resulting in the successful delivery of live infant at 35weeks of gestational age from intrauterine pregnancy following surgical removal of ruptured concurrent extrauterine pregnancy.
Early Diagnosis ; Embryonic Structures ; Female ; Fertilization ; Gestational Age ; Humans ; Incidence ; Infant ; Ovulation Induction ; Pregnancy ; Pregnancy, Heterotopic*

BACKGROUND: In-line intravenous filters have been used in intravenous administration sets of fluid to retain bacteria and bacterial endotoxin. We evaluated the effects of intravenous filters on Staphylococcus epidermidis, Pseudomonas aeruginosa, Candida and bacterial endotoxin retention. METHODS: S. epidermidis, C. albicans, P. aeruginosa and endotoxin were injected into each 10 bags of amino acid solution. After incubation for 24 and 72 hours, aspirates of 0.1 mL from 30 bags, with filtration and without filtration, were inoculated into culture media. The effluent from bags containing endotoxin was tested by limulus amebocyte lysate test. RESULTS: When effluents were filtered before culture, those from each 10 bags containing P. aeruginosa, C. albicans and endotoxin were sterile; also there was only one positive bacterial culture among 10 effluents from bags containing S. epidermidis. But by contrast all effluents without filtration showed positive cultures and endotoxin detection. CONCLUSION: This result showed that inline intravenous filters were useful device to remove bacteria, Candida, and bacterial endotoxin.
Administration, Intravenous ; Bacteria* ; Candida* ; Culture Media ; Filtration* ; Horseshoe Crabs ; Pseudomonas aeruginosa ; Staphylococcus epidermidis

Herpes Simplex Encephalitis is associated with a high mortality rate and a high probability of neurological sequelae. Good results are obtained when Herpes Simplex Encephalitis is promptly diagnosed and treated with antiviral agents. We reported a case of Herpes Simplex Encephalitis in which Magnetic Resonance Imaging (MRI), Single Photon Emission Computed Tomography (SPECT) and Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) were performed sequentially. Imaging studies are valuable tools for early detection and diagnosis of Herpes Simplex Encephalitis. And particularly FDG-PET represents functional anatomy through diffuse decline of glucose metabolism better than other imaging studies.
Antiviral Agents ; Diagnosis ; Encephalitis, Herpes Simplex* ; Glucose ; Herpes Simplex* ; Magnetic Resonance Imaging* ; Metabolism ; Mortality ; Tomography, Emission-Computed, Single-Photon*

We have done clinical analysis of 92 cases with chronic subdural hematoma, admitted to our department from August 1, 1984 to July 31, 1987. The following results were obtained; 1) The ratio of male versus female was 3.6:1, and 6 cases(71.7%) were over 50 year-old age. 2) 50 cases(75.7%) in older group(over 50) had head trauma history, and 11 cases(42.3%) in younger group(under 50). 3) The major clinical symptoms and signs in older group were mental deterioration and hemiparesis, in younger group headache and vomiting. 4) The hematoma densities in CT on admission were hyperdense 1.0%, isodense 33.7%, hypodense 39.3%, and mixed 25.9%. The shapes were biconvex 45.7%, planoconvex 35.8%, and crescenteric 18.5%. 5) The operation method was either burr hole drainage, or craniotomy with membranectomy, according to patient's physical condition and CT findings. In postoperative results there was no significant difference in both.
Craniocerebral Trauma ; Craniotomy ; Drainage ; Female ; Headache ; Hematoma ; Hematoma, Subdural, Chronic* ; Humans ; Male ; Middle Aged ; Paresis ; Vomiting

PURPOSE: Umbilical cord blood transplantation is a alternative method as new hematopoietic stem cell transplantation and has been performed clinically in indicated disease. However, it have the problems for long-term storage of cord blood in liquid nitrogen and for limited application to adult due to small amount of hematopoietic stem cell. Therefore, several centers have carried out active research for ex vivo expansion of cord blood stem cell. We investigated the hematopoietic function of cord blood plasma for development of new techniques. METHODS: We acquired the nucleated cells of cord blood from healthy infant and bone marrow from healthy donor received granulocyte-colony stimulating factor. We evaluated hematopoietic colony formation according to source of stem cell and plasma by semisolid culture medium. Three experimental groups were divided as source of plasma: group for cord plasma, group for bone marrow plasma, group for mixture of cord plasma and bone marrow plasma. RESULTS: The results were as follows: 1) The colony formation according to source of stem cell in commercialized standard semisolid culture medium showed that cord blood in the number of CFU-GM was less than bone marrow, but not significantly different in CFU-GEMM. 2) The colony formation according to source of stem cell in semisolid culture medium using experimental plasma showed that cord blood in the number of CFU-GM was more than bone marrow. There were no cytotoxic effect of plasma to experimental cells. 3) The colony formation in semisolid culture medium contained plasma according to experimental group showed that the number of CFU-GM in cord blood plasma was significantly more than bone marrow plasma in spite of different source of stem cell. Conclusions: These results suggested that cord blood might contain enough hematopoiesis to enable to perform transplantation compared with bone marrow and, also, cord blood plasma might be contributed more effective colony formation than bone marrow plasma. Therefore, we propose that it may be good to store cord blood cells with cord blood plasma in long-term storage. We will investigate the composition of hematopoietic growth factors and cytokines in cord blood plasma and the effect of cord blood plasma for ex vivo expansion of cord blood cells.
Adult ; Bone Marrow ; Bone Marrow Cells ; Cytokines ; Fetal Blood* ; Granulocyte-Macrophage Progenitor Cells ; Hematopoiesis ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells ; Humans ; Infant ; Intercellular Signaling Peptides and Proteins ; Myeloid Progenitor Cells ; Nitrogen ; Plasma* ; Stem Cells ; Tissue Donors