No abstract available.
Femoral Neck Fractures* ; Femur Neck* ; Humans ; Young Adult*

No abstract available.
Diagnosis* ; Foreign Bodies*

Sclerostomy is preferable full-thickness filtration surgery, if very low pressure are desired or if guard filtration surgery had failed. Laser sclerostomy can be performed in a less invasive manner than standard procedure, so it reduces scar formation and minimizes postoperative complications. The objective of this investigation was to determine the feasibility and parameters of laser sclerostomy using a diode laser. The diode laser with a fiberoptic delivery system is lightweight, portable and utilizes a 100 Volt outlet. Eighteen eyes of pigmented rabbits underwent a diode laser ab externo sclerostomy with energy 2 W, duration 1-2 seconds by applying endolaser probe, 0.5 mm from the limbus. Gross and histopathologic examination were done at 1 hour and 7 days after treatment. A patent fistula with formation of filtering bleb was achieved in all cases. There was a flattening of the filtration bleb at 3.3 postoperative days.
Blister ; Cicatrix ; Filtering Surgery ; Filtration ; Fistula ; Lasers, Semiconductor* ; Postoperative Complications ; Rabbits* ; Sclerostomy*

PURPOSE: Pathologic stage is the most accurate prognostic factor of renal cell carcinoma. We evaluated whether perirenal fat infiltration is a significant factor in tumors 7 cm or less in size. MATERIALS AND METHODS: We retrospectively reviewed the record of 164 cases of tumors 7 cm or less in size. We divided the patients into two groups according to the presence of perirenal fat infiltration (group A, pT1; group B, pT3a). We evaluated relationships, recurrence-free survival and disease-specific survival according to clinicopathologic parameters. Statistical differences were calculated by log-rank test. RESULTS: A total 131 patients were included in group A, with a mean age of 55.8 years, average tumor size was 4.2 cm, and a mean follow-up period of 43 months. Group B included 33 patients, with a mean age of 55.9 years, an average tumor size of 4.1 cm, and a mean follow-up period of 38 months. There was no significant difference in disease-specific survival; however, recurrence-free survival showed significantly different between two groups (group A: 95.5%, group B: 84.4%). CONCLUSION: In this study, perirenal fat infiltration proved to be an independent prognostic factor for predicting disease-free survival in patients with tumors of 7 cm or less in size. Therefore, as this study showed, the presence of perirenal fat infiltration requires stricter follow-up planning, even in small renal cell carcinoma.
Adipose Tissue ; Carcinoma, Renal Cell* ; Disease-Free Survival ; Follow-Up Studies ; Humans ; Neoplasm Invasiveness ; Prognosis ; Retrospective Studies

OBJECTIVE: The purpose of this study is to provide accurate understanding of clinical presentations and surgical outcomes as well as to identify the unique characteristics of lower lumbar osteoporotic compression fracture (OCF). METHODS: Clinical data were collected from 120 patients who had L3, L4 or L5 percutaneous vertebroplasty (PVP) performed from 2008 to 2012 at the single institute. L4 or L5 PVP patients were classified into group 1 and group 2 was for L3 PVP patients. Medical records were retrospectively investigated at 1 month after PVP. Long term follow-up results were obtained at a median value of 22 months after PVP. RESULTS: 75% of the patients in group 1 were not associated with traumatic events, 71% presenting with leg radiating symptoms and 46% requiring an additional decompressive surgery, more often than those in group 2. These differences are statistically significant (p<0.05). The short term medical record review demonstrated that only 73% of patients in group 1 were ameliorated with regard to back motion pain, whereas those in group 2 reported 87.7% rates of amelioration in identical category (p<0.05). The long term follow up confirmed a significantly worse outcome in group 1, with only 55.7% of patients reporting amelioration in their pain or functional status, but 71.7% rate of amelioration in group 2. CONCLUSION: The OCFs at the L4 or L5 level have different clinical characteristics from those at upper levels of the lumbar spine.
Follow-Up Studies ; Fractures, Compression* ; Humans ; Leg ; Medical Records ; Retrospective Studies ; Spine ; Vertebroplasty*

The characterisitic finding of hypertrophic cardiomyopathy is left ventricular hypertrophy without dilated chamber. Echocardiographic studies of patients with pheochromocytoma in the past have revealed both dilated and hypertrophic cardiomyopathies, as well as obstruction of the left ventricular outflow tract. We report this case because we experienced a pheochromocytoma patient who had reversible hypertrophic cardiomyopathy which might be related with circulating catecholamine level.
Cardiomyopathy, Hypertrophic* ; Echocardiography ; Humans ; Hypertrophy, Left Ventricular ; Pheochromocytoma*

PURPOSE: Free radicals are responsible for tissue injury in corneal preservation and transplantation. Morin hydrate, a flavonoid from Brazil wood, has been shown to be cytoprotective in several types of cells. The aim of this study was to investigate the effectiveness of morin hydrate on rabbit cornea against damage induced by oxyradicals and nitric oxide. METHODS: The rabbit cornea was studied in modified Ussing chambers to determine the effects of hydrogen peroxide (H2O2) or sodium nitroprusside (SNP) by measuring the bioelectrical properties (short-circuit current (Isc), tissue resistance (Rt) and potential difference (PD)). RESULTS: 1.0 mM H2O2 markedly increased the Isc at the tear side (T-side), but not at stromal side (S-side), suggesting the site of action of H2O2 was the apical membrane (T-side). After pretreatment with morin hydrate (T-side, 1.0 mM), H2O2-induced increase of Isc and PD was markedly reduced. In addition adding morin hydrate with H2O2 simultaneously, the increase of Isc and PD was also markedly reduced. Exposure of cornea to SNP at the T-side increased nitric oxide, and increased the bioelectrical properties (PD and Isc). This effect was attenuated by the treatment with morin hydrate. CONCLUSIONS: This study demonstrated that morin hydrate behaved as a antioxidant. This property of morin hydrate may help prevent protect cornea in preservative solutions from free radical damage.
Brazil ; Cornea ; Epithelium, Corneal* ; Free Radicals ; Hydrogen Peroxide ; Membranes ; Nitric Oxide ; Nitroprusside ; Oxygen* ; Wood

OBJECTIVES: To investigate correlation between risk factors of endometrial carcinoma and histopatholgic findings of endometrium. METHODS: We reviewed medical records of 148 postmenopausal women with abnormal uterine bleeding, who underwent endometrial biopsy from January 2009 to April 2010. Women who had hematologic disease, or had non-uterine pelvic diseases were excluded. Hormone therapy was performed in indicated subjects. Age, body mass index (BMI), associated diseases, endometrial thickness checked by transvaginal sonography, whether hormone therapy was used were reviewed according to endometrial histopathology. RESULTS: Mean age of the subjects was 58.9 +/- 8.4years old. Among the endometrial histopathologic findings, atrophic endometrium was the most common finding (32.7%), followed by hyperplastic endometrium (17.8%), endometrial carcinoma (10.4%), and endometrial polyp (9.2%). BMI was not correlation of the prevalence of endometrial carcinoma and endometrial hyperplasia. Mean endometrial thickness was 9.8 +/- 5.56 mm, while it was 14.0 +/- 5.89 mm in endometrial hyperplasia, and 16.0 +/- 6.56 mm in endometrial carcinoma. The prevalence of endometrial cancer was high in those whose endometrial thickness was more than 10 mm (P < 0.001). The prevalence of endometrial hyperplasia in those whose postmenopausal bleeding was related to hormone therapy was higher than of women in whom hormone therapy was not performed. However, there were no statistical significance. CONCLUSIONS: Postmenopausal bleeding must be considered as indicative of malignant disease until proven otherwise. Endometrial biopsy should be performed to exclude endometrial carcinoma in postmenopausal women whose endometrial thickness measured by transvaginal sonography is thick.
Biopsy ; Body Mass Index ; Endometrial Hyperplasia ; Endometrial Neoplasms ; Endometrium ; Female ; Hematologic Diseases ; Hemorrhage ; Humans ; Medical Records ; Polyps ; Prevalence ; Risk Factors ; Uterine Diseases ; Uterine Hemorrhage

PURPOSE: This study was conducted to identify the effectiveness of a preoperative comprehensive geriatric assessment (CGA) for predicting postoperative morbidity in elderly patients who underwent surgery for colorectal cancer. METHODS: Elderly patients (≥70 years old) who underwent surgery for colorectal cancer at a tertiary hospital in Korea were identified, and their cases were analyzed using data from a prospectively collected database to establish an association between major postsurgical complications and 'high-risk' patient as defined by the CGA. RESULTS: A total of 240 patients, with a mean age of 76.7 ± 5.2 years, were enrolled. Ninety-five patients (39.6%) were classified as "high-risk" and 99 patients (41.3%) as having postoperative complications. The univariate analysis indicated that risk factors for postoperative complications were age, American Society of Anesthesiologists physical status classification, serum hemoglobin, carcinoembryonic antigen, cancer stage, and "high-risk" status. The multivariable analyses indicated that "high-risk" status (odds ratio, 2.107; 95% confidence interval, 1.168–3.804; P = 0.013) and elevated preoperative carcinoembryonic antigen (odds ratio, 2.561; 95% confidence interval, 1.346–4.871, P = 0.004) were independently associated with postoperative complications. A multivariable analysis of the individual CGA domains indicated that high comorbidities and low activities of daily living were significantly related with postoperative complications. CONCLUSION: A preoperative CGA indicating "high-risk" was associated with major postoperative complications in elderly patients who underwent surgery for colorectal cancer. Thus, using the CGA to identify elderly colorectal-cancer patients who should be given more care during postoperative management may be clinically beneficial.
Activities of Daily Living ; Aged* ; Carcinoembryonic Antigen ; Classification ; Colorectal Neoplasms* ; Comorbidity ; Geriatric Assessment* ; Humans ; Korea ; Postoperative Complications ; Prospective Studies ; Risk Factors ; Tertiary Care Centers

Utilization of the colostomy site for laparoscopic reversal of Hartmann's procedure was recently introduced, and several studies have shown the feasibility of the procedure, which allows the colostomy site to serve as an access port for the operation. We demonstrate a method utilizing an accessory 5 mm trocar to assist in the operation while employing a colostomy-deepened glove port.
Colostomy* ; Laparoscopy ; Methods ; Surgical Instruments