1.Clinical Observations on Port - Wine Stains.
Seon Hoon KIM ; Heung Bae PARK
Korean Journal of Dermatology 1986;24(1):79-85
Although port-wine stains present as macular patches generally, some patients show considerable overgrowth of angiomatous tissue and show different results of laser therapy according to their histologic patterns. We observed 337 port-wine stain patients clinically, and tried to classify clinical morphology of port-wine stains and analyze with other features such as color, age and size. The results were as follows: Most of the lesions were located on the face, followed by neck, upper extremity, lower extremity and trunk in order. 2, On the face, the left lower part was the most frequent area of the lesions. The difference of the distribution between right and left side was not found, but the lesions were significantly more frequent on the lower part than the upper one. 3. The morphology was classified into patch, hypertrophic, cavernous and papular form according to therapeutic purpose. 4 When the color is darker, the others than the patch form appeared. 5, In old patients the color was darker and the papular form increased. 6. When the size enlarged, the hypertrophic form. increased. 7. Among ten patients who got the lesions at both the upper and lower eyelids, two showed ocular problems.
Coloring Agents*
;
Eyelids
;
Humans
;
Laser Therapy
;
Lower Extremity
;
Neck
;
Port-Wine Stain
;
Upper Extremity
;
Wine*
2.Evaluation of the Phototoxic Potential of Some Quinolone Antibiotics.
Yoon Hyang CHO ; Tae Heung KIM ; Heung Bae PARK ; Chul Kun PARK ; Kee Min PARK
Korean Journal of Dermatology 1995;33(6):1021-1028
BACKGROUND: The photsensitizing effect of quinolones has been recognized since their introdulation as an antibacterial agents. Recently several new second eneration antibacterial agents of this pharmacological class have become available for therapy, and are gaining increasing impotance. OBJECTIVE: To reveal the phototoxic potentials of some new quinolones by photohemolysis test, estimation of fluorescenc spectra, and Candida albicans test. METHODS: Nalidixic acid and four second-generation quinolones(ciprofloxacin, enoxacini, norfloxacin, and ofloxacitid were examined by fluorescence spertra which measured t.he phototoxc potentials by photochemial instability, photohemolsis test for the phototoxic properties against cell membranes and Candida tlbicans test for phototoxic properties against DNA. RESULTS: All drugs showed a fluorescence spectra within 360 nm to 450 nm, and in the photohemolysis test, all studied drug except ofloxacin got above 5% hemolytic value, and all drugs showed clear zone. in Candida albicans test after 48hours. CONCLUSION: These results suggested that all tested drugs were photochemically unstable. According to the mechanisris of cellular phototoxicity, ciprofloxacin, enoxacin, and norfloxacin was phtototoxic to nucleus and cell membrane, whereas ofloxacin was phototoxic to nucleus only.
Anti-Bacterial Agents*
;
Candida
;
Candida albicans
;
Cell Membrane
;
Ciprofloxacin
;
Dermatitis, Phototoxic
;
DNA
;
Enoxacin
;
Fluorescence
;
Nalidixic Acid
;
Norfloxacin
;
Ofloxacin
;
Quinolones
3.A Case of Reticulate Pigmented Anomaly of the Flexures.
Jai Il YOUN ; Heung Bae PARK ; Yoo Shin LEE
Korean Journal of Dermatology 1985;23(4):556-559
Reticulate pigmented anomaly of the Flexures (Dowling-Degos disease) is the rare pigment anomaly characterized by spotted and reticulate pigrnentation of the flexures. We report a case of reticulate pigmented anomaly of flexures in a 37-year-old woman. She had reticulated network of brown-black macules on right infrarnammary region and arm. Histopathological findings showed branching melanized epidermal downward proliferations arising from the lower border of epidermis.
Adult
;
Arm
;
Epidermis
;
Female
;
Humans
;
Pigmentation
4.A Case of Multiple Osteoma Cutis in Infant.
Heung Bae PARK ; Seon Hoon KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1986;24(5):722-725
The term "osteoma cutis" is limited only to primary cutaneous ossification in which there is no evidence of Albrights hereditary osteodystrophy in either the patient or his farnily. We herein present a case of osteorna cutis in a 2-year-old male. He had had multiple hard plaques on the extremities since birth and had not had the evidences of Albrights hereditary osteodystrophy and signs of secondary cutaneous ossification such as trauma, injection, previous skin lesions and abnormal laboratory findings. The histopathologic findings revealed bony spicules with numerous osteocytes, cement lines, Haversian canals, osteoblasts and osteoclasts.
Child, Preschool
;
Extremities
;
Haversian System
;
Humans
;
Infant*
;
Male
;
Osteoblasts
;
Osteoclasts
;
Osteocytes
;
Osteoma*
;
Parturition
;
Skin
5.Thin - Layer Chromatography Search for Disperce Yellow 3 and Disperce Orange 3 in 60 Brownish Stockings.
Heung Bae PARK ; Hee Chul EUN ; Yoo Shin LEE
Korean Journal of Dermatology 1988;26(3):298-305
Thin-layer (uni-dimensional and bi-dimensional) chrornatography studies were performed on 60 brownish stockings from 12 companies in Korea to search for Disperse Yellow 3 and Disperse Orange 3, which are known as common sensitizers in textiles. The results were as follows : 1) Mixture of various-colored dyes were being used to reveal the brownish hue in the stockings. 2) TLC demonstrated the presence of Disperse Yellow 3 in 53 stocking. 3) TLC demonstrated the presence of Disperse Orange 3 in 3 stockings, Although lack or more sophisticsted tests such as spectroseopic, infra red or nuclear spectra identification. These results suggest a strong clue to the presence of Disperse Yellow 3 and Disperse Orange 3 in the commercial stocking now being used in Korea.
Chromatography*
;
Citrus sinensis*
;
Coloring Agents
;
Korea
;
Textiles
6.MASTOPEXY AND REDUCTION MAMMOPLASTY THROUGH THE PERIAREOLAR INCISION.
Bae Won BAE ; So Ra KANG ; Heung Sik PARK ; Chin Ho YOON ; Han Joong KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1145-1152
No abstract available.
Female
;
Mammaplasty*
7.A Case of Bullous Lichen Planus.
Heung Bae PARK ; Yoo Chan KIM ; Kwang Hyun CHO ; Yoo Shin LEE
Korean Journal of Dermatology 1986;24(6):832-836
We herein present a case of bullous lichen planus in a 56-year-old female. She had had a generalized eruption of lichen planus with violaceus papules and plaques. many of which had been surmounted by vesicles and bullae. The histopathologic findings of a bulla revealed hyperkeratosis, irregular acanthosis, subepidermal bulla and upper dermal band-like cell infiltration. The patient had been treated with dapsone but the lesions had not been significantly improved.
Dapsone
;
Female
;
Humans
;
Lichen Planus*
;
Lichens*
;
Middle Aged
8.Detection of Human Papillomavirus DNA in Condylomata Acuminata Patients using Molecular Hybridization.
Kyoung Chan PARK ; Sang Hak LEE ; Yoo Shin LEE ; Young Kee KIM ; Heung Bae PARK ; Jeong Seon SEO
Korean Journal of Dermatology 1989;27(6):660-665
Condylomata acuminata are benign tumors which are mostly venereally transmitted. Common sites were coronal sulcus, perisnal area and prepuce. Among 28 patients, 21 acuminate lesions and 10 papular lesions were found. Twenty eight human genital warts in Korean were analysed by Southern blot hybridization. Sequences related to HPV6/11 are found in 89.3%(25/28) of the condylomata. HPV16 DNA was not found at sll. Subtype of HPV was determined by the restriction pattern of DNA cleaved with PstI restriction enzyme in 7 cases. Six cases of HPV6a and one case of HPV6c are found. The above results suggest that most of condylomata acuminata are caused by HPV6 and HPV11 in Korea.
Blotting, Southern
;
Condylomata Acuminata*
;
DNA*
;
Humans*
;
Korea
9.The Statistical Study of Patient with Acute Poisoning.
Heung Pyo KONG ; Kyoung Bae PARK ; Oh Kyung LEE ; Kang Suh PARK
Journal of the Korean Pediatric Society 1997;40(11):1596-1602
PURPOSE: The incidence of infectious disease, which has been the cause of death in pediatric period, was decreased. But, the opportunistic exposure to toxic substance shows a tendency to increase. We performed this study in order to find out preventive measures and the latest inclination of acute poisoning in childhood. METHODS: From January 1985 to July 1996, 88 children with acute drug and chemical poisoning, who diagnosed at Presbyterian Medical Center, were analyzed retrospectively. RESULTS: 1) It occurred more frequently in male than female (1.7:1) and high incidence was noted in 0-4 year-old age group (75%). 2) Annual distribution of poisoning shows a tendency to increased. 3) There was no significant seasonal difference in frequency of poisoning. 4) The vast majority (85%) of poison exposure were accidental and therapeutic intent was present in 7.5% of cases and suicidal intent was 7.5% of cases. 5) We noticed an hourly predominance with most accidents occurring from 9 a.m. to 1 p.m. and from 5 p.m. to 9 p.m., 35% respectively. 6) Categories with the largest numbers of total exposure, in descending order by exposure frequently, include the following : drug (30.1%), insecticide (20.4), rodenticide (12.9%), glacial acetic acid (13.9%), herbicide (4.3%), Carbon monoxide (3.2%), others (13%). So, food and household material are leading cause of poisoning, except drug. Of drug, DDS was the most common and then psychotherapeutic drugs were the next. 7) The chief complaints on admission were nausea and vomiting (32%), mental change (26%) irritability (9%), peripheral cyanosis (8%), seizure (5%), and in case of 20%, the patient were found incidentally without symptoms. 8) There were complications which were pneumonia, pulmonary fibrosis, esophageal stricture and pneumothorax. And death occurred in 4 cases, due to insecticide (2 cases), herbicide and rodenticide, 1 case respectively. CONCLUSIONS: In previous report in Korea, causative substance of poisoning were drug, carbone monoxide, insecticide, rodenticide in descending order. In our study, drug was the most common cause of poisoning. But it' s proportion was decreased compared with previous report, and carbone monoxide intoxication was markedly decreased. But, we noticed that the proportion of household material, such as glacial acetic acid and other household chemical, was increased. So, we should be pay more attention to poisoning and try to prevent them.
Acetic Acid
;
Carbon
;
Carbon Monoxide
;
Cause of Death
;
Child
;
Communicable Diseases
;
Cyanosis
;
Esophageal Stenosis
;
Family Characteristics
;
Female
;
Humans
;
Incidence
;
Korea
;
Male
;
Nausea
;
Pneumonia
;
Pneumothorax
;
Poisoning*
;
Protestantism
;
Pulmonary Fibrosis
;
Retrospective Studies
;
Seasons
;
Seizures
;
Statistics as Topic*
;
Vomiting
10.Multifocal eosinophilic granuloma in 6th decade: a case report.
Seong Bae KIM ; Seung Ki JEONG ; Hyung Joo KIM ; Je Yo HYUN ; Eon Sub PARK ; Heung Seek PARK
The Journal of the Korean Orthopaedic Association 1991;26(3):1006-1009
No abstract available.
Eosinophilic Granuloma*
;
Eosinophils*