From March 1985 to Sep.1985, Transcatheter hepatic arterial embolization was perfromed in 17 primary heptomaand 8 metstasis of liver in Department of Radiology, Yonsei University College of Medicine. Metastatic cancers ofliver were one nasopharyngeal cancer, one small bowel leiomyosarcoma, one gall bladder cancer and 5 colon cancers.The used embolization materials were the followings: Gelfoam particles for one primary hepatoma, 95% absoluteethanol for 4 patients, Ivalon(250-590micro m) for 19 patients and autologous blood clots for one metastasis, Theresults were summarized as the follows: 1. The devascularization of tumor vessels in post-emblization hepaticangiogram was complete in 6 primary hepatom and one metastasis and partial in 11 primary hepatoma and 7metastasis. 2. In the follow-up CT evaluation 3 to 4 weeks after embolization, well necrotic density was revealedin 8 primary hepatoma and one metastasis. 3. The complications were fever with higher than 38 degrees C(92%),abdominal pain (72%) and nausia or vomiting(40%). They were subsided wtihin one to 7 days after embolization. 4.In liver function study, sGOT and sGPT were elevated in 80% of total cases and returned to normal within 15 to 30days. LDH was variable. In 4 cases of absolute ethanol infusion, above liver enzymes were markedly elvated as 10times or more as normal range.
Alanine Transaminase ; Aspartate Aminotransferases ; Carcinoma, Hepatocellular ; Colon ; Ethanol ; Fever ; Follow-Up Studies ; Gallbladder Neoplasms ; Gelatin Sponge, Absorbable ; Hepatic Artery ; Humans ; Leiomyosarcoma ; Liver Neoplasms ; Liver ; Nasopharyngeal Neoplasms ; Neoplasm Metastasis ; Reference Values

PURPOSE: The purpose of this study is to assess the usefulness of combined intramedullary and extramedullay tibial resection guide system. MATERIALS AND METHODS: 277 consecutive total knee arthroplasties were performed using three different alignment systems.: extramedullary system(group 1 ; 89 cases) , intramedullary system(group 2;134 cases), combined system(group 3;54 cases). We compared the differences of these groups in terms of preoperative femorotibial angle, postoperative femorotibial angle and postoperative tibial component alignment angle, respectively. RESULTS: Preoperatively, the three groups were similar in diagnosis, patient age, and preoperative femorotibial angle(p>0.05). Postoperative tibial component alignment angle and femorotibial angle were similar in each group(p>0.05). The optimal tibial component alignment angle was defined within 2 degree of the 90 degree and it was achieved in 51.7% in group 1, 47.8% in group 2 and 59.3% in group 3(p>0.05). The the optimal femorotibial angle was defined by the range from valgus 5 degrees+/-2 and it was achieved in 54.5% in Group 1, 54.5% in Group 2 and 55.6% in Group 3(p>0.05). CONCLUSION: This study demonstrated that the accuracy of the extramedullary system, intramedullary system, and combination system for tibial resection were similar. So the combination system can be one of the acceptable method for cutting the proximal tibia, because it utilizes the strength of the extramedullary system as well as the intramedullary system.
Arthroplasty* ; Diagnosis ; Humans ; Knee* ; Tibia

To investigate the properties of ryanodine binding sites of the bird skeletal SR vesicles, SDS PAGE, purification of RyR, and (3H)ryanodine binding study were carried out in the SR vesicles prepared from the chicken pectoral muscle. The chicken SR vesicles have two high molecular weight (HMW) protein bands as in eel SR vesicles on SDS PAGE. The HMW bands on SDS PAGE were found in the (3H) ryanodine peak fraction (Fr3-5) obtained from the purification step of the ryanodine receptor protein. Bmax and KD of the chicken (3H)ryanodine binding sites were 12.52 pmol/mg protein and 14.53 nM, respectively. Specific (3H)ryanodine binding was almost maximal at 50~100 micrometer Ca2+, but was not increased by 5 mM AMP and not inhibited by high Ca2+. Binding was significantly inhibited by 20~100 micrometer ruthenium red and 1 mM tetracaine, but slightly inhibited by Mg2+. From the above results, it is suggested that chicken SR vesicles have the ryanodine binding sites to which the binding of ryanodine is almost maximal at 50~10 micrometer Ca2+, is significantly inhibited by ruthenium red and tetracaine, slightly inhibited by Mg2+, but not affected by AMP and not inhibited by high Ca2+.
Binding Sites* ; Birds ; Chickens* ; Eels ; Electrophoresis, Polyacrylamide Gel ; Molecular Weight ; Ruthenium Red ; Ryanodine ; Ryanodine Receptor Calcium Release Channel ; Sarcoplasmic Reticulum ; Tetracaine