A case of herpes simplex autoinoculated on the 1st interdigital web of right hand was reported, Herpes labialis characterized by confluent rice sized vesicular eruptions had developed on the midportion of upper lip. After 3 days, typical herpetic lesion occurred on the 1st interdigital web of right hand. We reviewed briefly the recent literatures.
Hand ; Herpes Labialis ; Herpes Simplex* ; Lip

Herpes simplex virus (HSV) esophagitis is a rare disease and most of cases are reported in the immunocompromised patients2,3,11,15,17,18). We report a case of fatal HSV infection started from herpes labialis and esophagitis. She had initially suffered from perioral ulcer, esophagitis, and interstitial pneumonitis later and eventually died of respiratory insufficiency one month later after the aneurysmal surgery. She did not have any immunocompromised medical history and also had no evidence of herpes encephalitis in laboratory study and magnetic resonance image (MRI). With the availability of effective agents for the treatment of HSV infection, early recognition of HSV esophagitis is important because it may be clinically confused with Cushing ulcer and may be complicated with a fatal pneumonitis.
Aneurysm ; Encephalitis, Herpes Simplex ; Esophagitis ; Herpes Labialis ; Herpes Simplex* ; Lung Diseases, Interstitial ; Pneumonia* ; Rare Diseases ; Respiratory Insufficiency ; Simplexvirus ; Ulcer

Eczema herpeticum is a herpes simplex virus infection with disseminated skin involvement, which superimposes on a pre-existing dermatosis. Two siblings with simultaneous primary herpes simplex virus (HSV) infection on the normal skin of their backs, followed by their mother's herpes labialis. Eczema herpeticum was diagnosed on the basis of history, clinical feature, Tzanck test, histologic examination and a serologic test. Their skin lesions were healed by treatment with oral acyclovir and mupirocin ointment.
Acyclovir ; Eczema* ; Herpes Labialis ; Humans ; Kaposi Varicelliform Eruption* ; Mupirocin ; Serologic Tests ; Siblings* ; Simplexvirus ; Skin Diseases ; Skin*

Herpes simplex virus infection of the hand in children occurs after auto-inoculation from herpetic gingivostomatitis or herpes labialis. Herpetic whitlow should be suspected based on clinical signs. Diagnosis can be made by PCR or virus culture. Many misdiagnosed cases suggests that this disease is not sufficiently known. Surgical interventions may be harmful and should be avoided. We report a case of herpetic whitlow with bacterial superinfection in a three-year-old girl.
Child ; Diagnosis ; Female ; Hand ; Herpes Labialis ; Humans ; Polymerase Chain Reaction ; Simplexvirus ; Stomatitis, Herpetic ; Superinfection*