No abstract available.
Hepatopulmonary Syndrome* ; Lung* ; Perfusion*

No abstract available.
Echocardiography ; Hepatopulmonary Syndrome*

Report a case of 4 years old girl lived in Gia Lai province, admitted Hospital of Pediatrics No 2 at December 6th 2004. 3 days before admitting hospital, she had some symptoms including hemorrhagic vomiting, melena, and then was admitted Gia Lai Hospital. She was diagnosed with upper digestive hemorrhage, and treated by hypodermoclysis and fresh blood transfusion. Hemogram test discovered anemia. Pulmonary X ray had no abnormal image. Abdominal color Doppler ultrasound revealed images of cirrhosis and portal hypertension, large spleen. The spiral chest CT scan found that no abnormal pulmonary vessel. Patient was treated by endoscopic sclerosis of esophageal varices, and administration of Axepim and gentamycine based on antibiotic susceptibility test. Results of microbiological test after treatment was negative
Hepatopulmonary Syndrome ; Child ; Hypertension

Animals ; Hepatopulmonary Syndrome ; diagnosis ; etiology ; therapy ; Humans ; Liver Transplantation

Hepatopulmonary syndrome (HPS) and portopulmonary hypertension (PPHTN) are complications of portal hypertension and cirrhosis. Their pathophysiological mechanisms clearly differ. HPS is characterized by a defect in arterial oxygenation induced by pulmonary vascular dilatation. In contrast, PPHTN is predominantly due to excessive pulmonary vasoconstriction and vascular remodeling, but is rarely associated with hypoxia. We report a case of a patient who had both HPS and PPHTN at the time of presentation. HPS was aggravated after sildenafil administration for the treatment of PPHTN. We demonstrated increased amount of intrapulmonay shunt after sildenafil challenge by using agitated saline contrast transthoracic echocardiography.
Anoxia ; Dihydroergotamine ; Dilatation ; Echocardiography ; Fibrosis ; Hepatopulmonary Syndrome* ; Humans ; Hypertension* ; Hypertension, Portal ; Oxygen ; Vasoconstriction ; Sildenafil Citrate

Intracardiac metastasis of hepatocellular carcinoma with functional tricuspid valve stenosis is not common. Furthermore, hepatopulmonary syndrome associated with hepatocellular carcinoma is rarely encountered. We present a case of intracardiac metastasis of hepatocellular carcinoma presenting with functional tricuspid valve stenosis accompanied with hepatopulmonary syndrome.
Carcinoma, Hepatocellular ; Echocardiography ; Heart Ventricles ; Hepatopulmonary Syndrome ; Neoplasm Metastasis ; Tricuspid Valve ; Tricuspid Valve Stenosis

Blood Gas Analysis ; Hepatopulmonary Syndrome ; therapy ; Humans ; Male ; Middle Aged ; Portasystemic Shunt, Transjugular Intrahepatic ; Treatment Outcome

The present paper was aimed to study the role of spleen tyrosine kinase (Syk) in angiogenesis in hepatopulmonary syndrome (HPS) and the underlying mechanism. Sprague Dawley (SD) rats were randomly divided into three groups: sham operation group (sham group), common bile duct ligation (CBDL) 5-week group (5W group) and R788 intervention group (R788 group). HPS model was established by CBDL. Rats in R788 group were intraperitoneally injected with R788 (20 mg/kg) once daily to week 5 after CBDL operation. The protein expression levels and distribution of Syk, p-Erk1/2, and p-Akt in lung tissue were detected by Western blot and immunohistochemistry. Immunofluorescence staining was used to observe the location of Syk expression and the number of angiogenesis in lung tissue. The results showed that, compared with sham group, 5W group exhibited up-regulated protein expression level of Syk, increased phosphorylation levels of Erk1/2 and Akt, and increased number of pulmonary microvessels. Compared with 5W group, R788 group exhibited down-regulated protein expression level of Syk, decreased phosphorylation levels of Erk1/2 and Akt, and decreased number of pulmonary microvessels. These results suggest that Syk may promote pulmonary angiogenesis in HPS model rats by activating downstream Erk1/2 and Akt signaling pathways, which provides a theoretical basis and potential drug therapeutic targets for the clinical treatment of HPS.
Animals ; Disease Models, Animal ; Hepatopulmonary Syndrome ; Lung ; Rats ; Rats, Sprague-Dawley ; Syk Kinase

Humans ; Hepatopulmonary Syndrome/surgery* ; Liver Transplantation/adverse effects* ; Extracorporeal Membrane Oxygenation/adverse effects* ; Postoperative Complications ; Patients

Pulmonary arteriovenous fistula (PAVF) is a complication of the Glenn shunt. A 57-year-old tetralogy of Fallot (TOF) patient, who had undergone a Glenn shunt and TOF total correction, complained of dyspnea and cyanosis. PAVFs were present in the right lung, and right lung perfusion was nearly absent. After coil embolization, takedown of the Glenn shunt, and reconstruction of the right pulmonary artery, the patient's symptoms were relieved. Extrapulmonary radioisotope uptake caused by the PAVFs shown in lung perfusion scans decreased, and right lung perfusion increased gradually. Although the development and resolution of PAVFs after a Glenn shunt have been reported in the pediatric population, this may be the first report on this change in old age.
Arteriovenous Fistula* ; Cyanosis ; Dyspnea ; Embolization, Therapeutic ; Fontan Procedure ; Hepatopulmonary Syndrome ; Humans ; Lung ; Middle Aged* ; Perfusion ; Pulmonary Artery ; Tetralogy of Fallot*