1.Hepatoblastoma.
Korean Journal of Pediatrics 2004;47(Suppl 2):S456-S462
No abstract available.
Hepatoblastoma*
2.A rare case of mixed adult Hepatoblastoma mimicking as Hepatocellular Carcinoma
Journal of the Philippine Medical Association 2022;101(1):51-55
Hepatoblastoma (HB) is a rare pediatric
malignant tumor of the liver. Most of these tumors arise in the embryo and this is usually discernible in the first 3 years of life; thus, its occurrence in the adult population seems to be unusual. We present this case due to its rarity and its potential to mimic other primary liver tumors in adults such as HCC. To the best of our knowledge with literature review, there are only 40 cases of adult HB reported worldwide.
In this paper, we report a case of a 49-year-old female, diagnosed with Chronic Hepatitis B, admitted due to abdominal pain. Physical examination revealed hepatomegaly. Liver function test was unremarkable.
AFP was elevated at >50,000ng/mI. Triphasic CT scan revealed a hypodense mass in the right lobe of the liver measuring approximately 11 × 11 × 13cm suggestive of HCC. Subsequently, patient underwent right hepatectomy. Pathological examination, however, demonstrated that the tumor showed a malignant neoplasm with epithelial and mesenchymal components consistent with adult HB, mixed type.
Since treatment
of adult HB is not yet established, studies have suggested that it is logical to follow the treatment protocol for childhood HB. Hence, this patient underwent chemotherapy with Cisplatin, Vincristine and 5-Fluorouracil.
The low incidence of HB in adults presents a
diagnostic challenge, requiring a high index of suspicion and a thorough evaluation. Since prognosis could be improved with early detection and treatment, it is important for clinicians not to overlook HB.
Hepatoblastoma
;
Hepatomegaly
3.A Case of Hepatoblastoma.
Journal of the Korean Pediatric Society 1977;20(1):62-64
A case of hepatoblastoma, disgnosed with biopsy in a two-year-old male is reported with a short review of the literature.
Biopsy
;
Hepatoblastoma*
;
Humans
;
Male
4.1 Case of chromosome 1q deletion with sialoblastoma and hepatoblastoma in neonate.
Chu Yeop HUH ; Hye Jin CHOI ; Seung Bo KIM ; Sun LEE ; Sung Jik LIM ; Moon Ho YANG
Korean Journal of Obstetrics and Gynecology 1999;42(1):175-178
Sialoblastoma and hepatoblastoma of neonate were very rare cancer. We present a case of concurrent sialoblastoma with hepatoblastoma associated with chromosomal anomaly.
Hepatoblastoma*
;
Humans
;
Infant, Newborn*
5.A Case of the Hepatoblastoma with Precocious Puberty.
In Young PARK ; Byung Jun LEE ; Byung Churl LEE
Journal of the Korean Pediatric Society 1989;32(5):735-740
No abstract available.
Hepatoblastoma*
;
Puberty, Precocious*
6.Hepatoblastoma with Rupture and Hemorrhage.
Kwang Wook KO ; Hyung Ro MOON ; Je Geun CHI ; Kwi Won PARK
Journal of the Korean Pediatric Society 1985;28(12):1261-
No abstract available.
Hemorrhage*
;
Hepatoblastoma*
;
Rupture*
7.Loss of Heterozygosity of p73, APC, and p53 in Hepatoblastoma.
Han Seong KIM ; Young Mi JUNG ; Mi Ran KIM ; Jung Young LEE ; Mi Sook LEE ; Ja June JANG
The Korean Journal of Hepatology 1999;5(1):43-49
BACKGROUND/AIMS: The status of tumor suppression gene can be assessed indirectly by analyzing the loss of heterozygosity. Hepatoblastoma is a malignant liver tumor in childhood. To find the molecular carcinogenetic mechanism of hepatoblastoma, loss of heterozygosity (LOH) of p73, APC and p53 was studied. MATERIALS AND METHODS: Hepatoblastoma tissues from thirty-three cases were collected by lobectomy or tumorectomy. On H- stained sections, normal and tumor cells were microdissected separately and LOH analysis was perfomed using 8 markers: six of p73, one of APC and one of p53. RESULTS: Number of cases showing at least one LOH in six p73 markers was four out of twenty- six (15.4%): each LOH frequencies in D1S160, D1S170, D1S199, D1S228, D1S243 and D1S253 were in order of 7.7%, 0%, 9.1%, 0%, 12.5% and 0%. LOH frequency of APC was 41.7% and that of p53 was 13.3%. CONCLUSION: Low LOH frequency of p73 related markers indicates that p73 gene may not be implicated in carcinogenesis of hepatoblastoma.
Carcinogenesis
;
Hepatoblastoma*
;
Liver
;
Loss of Heterozygosity*
8.A Case of Successful Hepatic Resection after Local Radiotherapy with Combined Transarterial Chemoinfusion in Hepatoblastoma .
Airi HAN ; Jung Tak OH ; Seok Joo HAN ; Seung Hoon CHOI ; Eui Ho HWANG
Journal of the Korean Association of Pediatric Surgeons 2001;7(1):64-67
It has been widely accepted that complete surgical resection of hepatoblastoma is essential for long-term survival. But unfortunately less that 50% of hepatic tumors in children can be totally removed at the time of diagnosis. This report is to present the experience of successful resection of hepatoblastoma after concurrent radiotherapy with transarterial chemoinfusion in a child. We believe this modality of treatment enables complete resection of unresectable hepatoblastoma, which is resistant to the systemic chemotherapy.
Child
;
Diagnosis
;
Drug Therapy
;
Hepatoblastoma*
;
Humans
;
Radiotherapy*
9.Study on the effect of various factors for the growth of human hepatocellular carcinoma, hepatoblastoma cell lines.
Gi Duk KIM ; Jae Gahb PARK ; Soo Tae KIM
Journal of the Korean Cancer Association 1991;23(1):83-100
No abstract available.
Carcinoma, Hepatocellular*
;
Cell Line*
;
Hepatoblastoma*
;
Humans*
10.Hepatoblastoma in a Patient with Familial Adenomatous Polyposis: Case Report.
Tae Eun KIM ; Jang Ho KIM ; Il Ki LEE ; Jung Heon HONG ; Ik Soo KIM
Journal of the Korean Radiological Society 2004;50(2):119-122
Familial adenomatous polyposis and hepatoblastoma are rare conditions; the latter is closely related to the FAP gene. We describe the imaging findings of hepatoblastoma in a patient with polyposis coli.
Adenomatous Polyposis Coli*
;
Colonic Neoplasms
;
Hepatoblastoma*
;
Humans