1.A Study on Viral Hepatitis Markers and Abnormal Liver Function Test in Adults Living in Northwest Area of Chungnam.
Suk Bae KIM ; Won Kyung LEE ; Hoon CHOI ; So Mi KIM ; Rhan NOH ; Ha Yan KANG ; Sang Suk LEE ; Sung Soo RA ; Jae Hwan GONG ; Hyun Duk SHIN
The Korean Journal of Gastroenterology 2009;53(6):355-360
BACKGROUND/AIMS: We studied the prevalence of chronic hepatitis B, C and abnormality on liver function among the population in northwest area of Chungnam. METHODS: We have reviewed 40,112 adults who had received medical examination at health promotion center in Dankook university hospital. We studied them retrospectively about HBsAg, HBsAb, anti-HCV, and liver function test (LFT). RESULTS: Among the study subjects, 22,936 men and 17,176 women were involved. The overall seroprevalence of HBsAg was 4.2%. The prevalence in men (4.5%) was higher than that of women (3.7%) (p<0.001). The seroprevalence of HBsAg in their age was 5.1% in the 5th decade, 4.2% in the 2nd decade, 4.1% in the 4th decade, and 4.1% in the 6th decade. The overall seroprevalence of HBsAb was 65.1%. The overall seroprevalence of anti-HCV was 0.7%. After we reexamined them with HCV RNA or RIBA (Recombinant Immunoblot Assay), the prevalence of chronic hepatitis C was 0.09%. The LFT abnormality in total subjects was 11.4%. The LFT abnormality of chronic hepatitis B and C subjects was 21.72% and 63.2%. CONCLUSIONS: The prevalence of chronic hepatitis B and C was lower than that of previous studies. The prevalence of chronic hepatitis B in the 2nd decade was still high.
Adolescent
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Adult
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Aged
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Aged, 80 and over
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Child
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Female
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Hepatitis B Antibodies/blood
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Hepatitis B Surface Antigens/blood
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Hepatitis B, Chronic/*epidemiology/immunology/physiopathology
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Hepatitis C Antibodies/blood
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Hepatitis C, Chronic/*epidemiology/immunology/physiopathology
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Humans
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Korea
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Liver Function Tests
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Male
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Middle Aged
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Prevalence
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RNA, Viral/blood
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Retrospective Studies