1.Coagulation changes in patients with moderate acute hepatitis.
Journal of Practical Medicine 2002;430(9):14-17
A study on the coagulation changes in 31 patients with moderate acute hepatitis B in the Army Central hospital 108 and the Institute of Clinical Medicine and Tropical diseases has shown that activated partial thromboplastin time (APTT) was prolonged, the prothrombin rate and the coagulant factors of II,VII and X were moderately reduced during stage of complete crisis and reversed during remission stage. The coagulant factor V was not be influenced. Number of thrombocyte and concentrations of compounds FDF, D-dimer from decomposition of fibrin/fibrinogen was normal.
Hepatitis
;
Blood Coagulation
2.HCV infection among haemodialysis patients and some subjects who have relationship with blood transfusion in Vietnam.
Journal of Vietnamese Medicine 2001;267(12):13-18
Screening anti- HCV for blood donors has been done in Vietnam since 1995. However up to now, many blood transfusion centers at provincial and district levels still have not been able to screen HCV for blood donors due to lack of equipment and test kits. Besides that, there are a few studies on the more studies on that area, especially for blood donors. In this study, we had identified anti-HCV for four subject groups by using ELISA technique with diagnostic tests of GBC company. The results showed that percentage of anti-HCV positive among donors who had more than one time blood donation at NIHBT is lower than that among first -time blood donors (0.47 vs 1.53) with a statistical significance P<0.01. This difference can be explained that donors who have more than one-time blood donation at NIHBT have been screened for HCV at NIHBT before. On the other hand, prevalence of HCV infection among patients who had received blood many times are very high (more than 50%). It also shows that excluding blood samples with HCV infection is very important
Hepatitis C
;
Blood Transfusion
3.Positive rate of antibody to hepatitis C virus in ALT-elevated blood donors.
Hyun Ok KIM ; Min Ja CHOI ; Hyon Suk KIM ; Samuel Y LEE ; Young Chul OH
Korean Journal of Blood Transfusion 1991;2(1):51-56
No abstract available.
Blood Donors*
;
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
;
Humans
5.Qualitative detection of hepatitis C virus core antigen in the serum in patients with chronic hepatitis C.
Yi OUYANG ; De-ming TAN ; Tie-gang LI ; Hui ZHOU ; Chang TAN
Journal of Central South University(Medical Sciences) 2006;31(6):894-905
OBJECTIVE:
To evaluate the clinical significance of serum hepatitis C virus (HCV) core antigen detected by enzyme linked immunosorbent assay (ELISA).
METHODS:
The serum HCV core antigen, which was taken from 149 patients with chronic hepatitis C, 20 patients of chronic hepatitis B and 20 health volunteers, was detected by ELISA. Meanwhile, the serum HCV RNA was detected by RT-PCR, and anti-HCV was detected by ELISA.
RESULTS:
The qualitative HCV core antigen in the serum, which was take from 20 patients of chronic hepatitis B and 20 health volunteers, was negative.The positive percentage of HCV core antigen was 49.66% in the 149 sera of patients with chronic hepatitis C. The coincidence of detective results of HCV RNA and HCV core antigen was 54.36%, without significant difference (P>0.05). The positive percentage of HCV RNA and HCV core antigen in the 149 anti-HCV antibody positive sera samples were 55.03% (82/149) and 49.66% (74/149), respectively, and there was no significant difference (P>0.05).
CONCLUSION
The qualitative HCV core antigen detected by ELISA has a high specificity. The positive percentage of HCV core antigen in the serum of patients with chronic hepatitis C is 49.66%. HCV core antigen is related to HCV RNA. HCV core antigen may be a useful serum marker which could show HCV viraemia like HCV RNA.
Hepatitis C Antigens
;
blood
;
Hepatitis C, Chronic
;
blood
;
Humans
;
RNA, Viral
;
blood
;
Viral Core Proteins
;
blood
6.Rate of HBsAg and anti-HCV carriers among blood donors at Thua Thien Hue province during 5 years 1997 - 2001
Journal of Practical Medicine 2002;435(11):12-14
The rate of HBsAg carriers among blood donors at at Thua Thien Hue province during 5 years (1997 - 2001) is relative high, with 13.57% on average. At the same time, the incidence of HCV infection is lower than other areas (with mean 0.64%). The rate of HBsAg carrier is higher in rural than in Hue city (14.72% vs. 12.27%). The young adults in precincts have higher HBsAg incidence than in other groups.
Blood Donors
;
Hepatitis B Surface Antigens
;
Hepatitis C Antibodies
7.Relation of HIV, HCV and HBsAg between patients and blood donors
Journal of Practical Medicine 2002;430(9):58-60
In 1997, the Blood Bank in ViÖt §øc hospital discovered 14 cases of HIV1 positive: 1 case was not enough serum to make further test, 1 was regular donor with HIV positive, Anti HCV negative, HBsAg negative. The incidence of Anti HCV (Hepatitis C) was 12/13 positive (92.3%). The incidence of heroin users was 12/13 (92.3%). The incidence of HBsAg (Hepatitis B) was: 1/13 positive (7.8%).
HIV
;
Hepatitis C virus
;
Hepatitis B Surface Antigens
;
Blood Donors
8.Prevalence of antibody to hepatitis C virus in blood donors in Incheon area.
Hwa Ryung CHUNG ; Myung Hee KIM ; Hyon Suk KIM
Korean Journal of Clinical Pathology 1991;11(2):469-473
No abstract available.
Blood Donors*
;
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
;
Humans
;
Incheon*
;
Prevalence*