1.Functional & anatomic reconstruction of the donor site after the transverse rectus abdominis myocutaneous(TRAM) flap transfer.
Jeong Seob YOON ; Hur Bum LEE ; Sang Heon LEE ; Keuk Shun SHIN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(3):459-469
No abstract available.
Humans
;
Rectus Abdominis*
;
Tissue Donors*
2.A Clinical Experience of Continuous Ambulatory Peritoneal Dialysis in Child.
Heon Seob SONG ; Byung Sook PARK ; Kyung Jin SHIN ; Beyong Sang CHOI ; Dae Yeol LEE
Journal of the Korean Pediatric Society 1987;30(5):560-568
No abstract available.
Child*
;
Humans
;
Peritoneal Dialysis, Continuous Ambulatory*
3.Clinical study on intranasal injection of steroid in allergicrhinitis.
Ho Joon LEE ; Heon Sang SHIN ; Gyu Dong CHOI ; Gun Young MUN ; Chul Ho CHANG
Journal of the Korean Academy of Family Medicine 1991;12(2):28-31
No abstract available.
4.Clinical application of 40Hz event related potential for audiometry.
Seong Heon SHIN ; Sang Heun LEE ; Jin Sin CHOO ; Tae Whan CHO ; Chang Sup SEONG
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):690-696
No abstract available.
Audiometry*
5.Leptomeningeal Metastasis in Gliomas : Clinical Characteristics and Risk Factors
Jeyul YANG ; Ji-Woong KWON ; Sang Hoon SHIN ; Heon YOO ; Kyu-Chang WANG ; Sang Heyon LEE ; Ho-Shin GWAK
Journal of Korean Neurosurgical Society 2023;66(4):465-475
Objective:
: Our objective is to analyze the occurrence, clinical course and risk factors for glioma patients with leptomeningeal metastasis (LM) according to different metastasis patterns and clinical variables.
Methods:
: We retrospectively reviewed data from 376 World Health Organization (WHO) grade II–IV adult glioma patients who were treated in the National Cancer Center from 2001 to 2020. Patients who underwent surgery at other institutions, those without initial images or those with pathologically unconfirmed cases were excluded. LM was diagnosed based on magnetic resonance imaging (MRI) findings or cerebrospinal fluid (CSF) cytology. The metastasis pattern was categorized as nodular or linear according to the enhancement pattern. Tumor proximity to the CSF space was classified as involved or separated, whereas location of the tumor was dichotomized as midline, for tumors residing in the thalamus, basal ganglia and brainstem, or lateral, for tumors residing in the cerebral and cerebellar hemispheres.
Results:
: A total of 138 patients were enrolled in the study. A total of 44 patients (38%) were diagnosed with LM during a median follow-up of 9 months (range, 0–60). Among the clinical variables, tumor proximity to CSF space, the location of the tumor and the WHO grade were significant factors for LM development in univariate analysis. In multivariate analysis, the midline location of the tumor and WHO grade IV gliomas were the most significant factor for LM development. The hazard ratio was 2.624 for midline located gliomas (95% confidence interval [CI], 1.384–4.974; p=0.003) and 3.008 for WHO grade IV gliomas (95% CI, 1.379–6.561; p=0.006).
Conclusion
: Midline location and histological grading are an important factor for LM in glioma patients. The proximity to the CSF circulation pathway is also an important factor for WHO grade IV glioma LM. Patients carrying high risks should be followed up more thoroughly.
6.Clinical Experience of Bevacizumab for Radiation Necrosis in Patients with Brain Metastasis
Moowan PARK ; Ho-Shin GWAK ; Sang Hyeon LEE ; Young Joo LEE ; Ji-Woong KWON ; Sang-Hoon SHIN ; Heon YOO
Brain Tumor Research and Treatment 2020;8(2):e11-
Background:
As the application of radiotherapy to brain metastasis (BM) increases, the incidence of radiation necrosis (RN) as a late toxicity of radiotherapy also increases. However, no specific treatment for RN is indicated except long-term steroids. Here, we summarize the clinical results of bevacizumab (BEV) for RN.
Methods:
Ten patients with RN who were treated with BEV monotherapy (7 mg/kg) were retrospectively reviewed. RN diagnosis was made using MRI with or without perfusion MRI. Radiological response was based on Response Assessment in Neuro-Oncology criteria for BM. The initial response was observed after 2 cycles every 2 weeks, and maintenance observed after 3 cycles every 3-6 weeks of increasing length intervals.
Results:
The initial response of gadolinium (Gd) enhancement diameter maintained stable disease (SD) in 9 patients, and 1 patient showed partial response (PR). The initial fluid-attenuated inversion recovery (FLAIR) response showed PR in 4 patients and SD in 6 patients. The best radiological response was observed in 9 patients. Gd enhancement response was 6 PR and 3 SD between 15-43 weeks. Reduction of FLAIR showed PR in 5 patients and SD in 4 patients. Clinical improvement was observed in all but 1 patient. Five patients were maintained on protocol with durable response up to 23 cycles. However, 2 patients stopped treatment due to primary cancer progression, 1 patient received surgical removal from tumor recurrence, and 1 patient changed to systemic chemotherapy for new BM. Grade 3 intractable hypertension occurred in 1 patient who had already received antihypertensive medication.
Conclusion
BEV treatment for RN from BM radiotherapy resulted in favorable radiological (60%) and clinical responses (90%). Side effects were expectable and controllable. We anticipate prospective clinical trials to verify the effect of BEV monotherapy for RN.
7.Giant Invasive Intraosseous Schwannoma in Lumbar Spine.
Seong Cheol PARK ; Heon YOO ; Sang Hoon SHIN ; Seung Hoon LEE
Korean Journal of Spine 2009;6(3):214-217
A rare case of giant invasive intraosseous schwannoma in lumbar vertebra with no neurologic deficit is reported. This tumor had vertebral body, left paravertebral tissue and lamina invasion and thus classified as type V giant invasive schwannoma according to Sridhar's classification of benign nerve sheath tumor. Because intraosseous portion was significantly larger than extraosseous portion, this tumor was mentioned as intraosseous schwannoma. Tumor was successfully resected using corpectomy, mesh cage insertion and posterior fixation. Pathological diagnosis was benign schwannoma.
Neurilemmoma
;
Neurologic Manifestations
;
Spine
8.A Case of Renal Angiomyolipoma Extending into the Renal Cyst Which was Confused with Renal Pelvis Tumor.
Sung Gi MIN ; Heon Seong LEE ; Sang Jae KANG ; Se Jong SHIN
Korean Journal of Urology 1995;36(1):110-113
Renal angiomyolipoma is composed of mature fats, smooth muscles and abnormal blood vessels which arises mainly from renal parenchyme and compresses the calyx or protrudes the renal cortex, but which extends into the renal cyst is rare. Recently it can be easily diagnosed preoperatively by several diagnostic modalities such as ultrasonography, computed tomography and several clinical signs associated with tuberous sclerosis, although it`s clinical and radiological features are similar with renal cell carcinoma. We report a case of renal angiomyolipoma without tuberous sclerosis, extending into the renalcyst, which was confused with renal pelvis tumor in a 73 years old male.
Aged
;
Angiomyolipoma*
;
Blood Vessels
;
Carcinoma, Renal Cell
;
Fats
;
Humans
;
Kidney
;
Kidney Pelvis*
;
Male
;
Muscle, Smooth
;
Tuberous Sclerosis
;
Ultrasonography
9.Clinical evaluation of urethral strictures following urethral catheterization.
Hwan Sik CHOI ; Heon Seong LEE ; Sang Jae KANG ; Se Jong SHIN
Korean Journal of Urology 1992;33(4):706-709
A clinical evaluation was made on 19 patients with urethral stricture following urethral catheterization in 155 urethral stricture patients during 12 years from January. 1979 to December. 1990. The following results were obtained. I. In 155 cases of urethral stricture, iatrogenic urethral stricture was 24 cases (15.4%) of which the most common cause was urethral catheterization(19 cases) and followed by instrumentation (2 cases). 2. In 19 cases of urethral stricture following urethral catheterization. the most common site was the anterior urethra (bulbous 10 cases. pendulous 7 cases) and multiple strictures showed 5 of 17 anterior urethral strictures. 3. In 19 cases, 16 cases (84.2%) occurred in patients who have kept the urethral catheter within seven days and 18 cases (94.7%) were inserted and cared the urethral catheter by non-urologist. 4. Treatment was performed internal urethrotomy in 16, dilatation in 2 and catheter indwelling during 1 week in 1. 5. In 24 cases of iatrogenic urethral stricture. mean number of dilation to recurrent strictures after primary procedure had required O.5 time. From our results. we suggest that education for the careful insertion and method of care for the urethral catheter to non-urologist is least likely to induce urethral stricture formation.
Catheters
;
Constriction, Pathologic
;
Dilatation
;
Education
;
Humans
;
Urethra
;
Urethral Stricture*
;
Urinary Catheterization*
;
Urinary Catheters*
10.A case of ureteral ectopia draining into seminal vesicle.
Heon Seong LEE ; Sang Jae KANG ; Se Jong SHIN ; Sung Hyup CHOI
Korean Journal of Urology 1993;34(1):165-168
Ectopic ureter entering into the seminal vesicle associated with ipsilateral renal dysplasia is a very rare developmental abnormality. Clinical manifestations consists of dysuria, hematuria, recurrent epididymitis. ejaculatory pain and perineal discomfort and the diagnosis is made by seminal vesiculogram through vas deference. Surgical excision of the seminal vesicle and the ectopic ureter is the best choice or treatment in this entity. We present a case of 34 year old infertile man with ectopic ureter entering into the seminal vesicle associated with ipsilateral renal dysplasia and contralateral cryptorchidism.
Adult
;
Cryptorchidism
;
Diagnosis
;
Dysuria
;
Epididymitis
;
Hematuria
;
Humans
;
Male
;
Seminal Vesicles*
;
Ureter*