No abstract available.
Killer Cells, Natural* ; Lymphocytes* ; Lymphocytes, Null* ; Schizophrenia*

OBJECTIVES: The pathophysiology of restless legs syndrome (RLS) is not obvious, but many promising theories involve dopaminergic deficiency and genetic causes. The RLS is presumed to occur more frequently among schizophrenic patients who take antipsychotics, most of which blocks the dopamine receptors. This study aimed to investigate whether dopamine transporter gene (DAT1) 40 base pair (bp) variable number of tandem repeat (VNTR) polymorphism is associated with the antipsychotic-induced RLS in schizophrenia. METHODS: We determined the diagnosis of RLS among the 190 Korean schizophrenic patients by the diagnostic criteria of the International Restless Legs Syndrome Study Group (IRLSSG). Genotyping was performed for the 40bp VNTR in DAT1 gene using polymerase chain reaction. RESULTS: We separated the schizophrenic patients into 44 patients with RLS and 146 patients without RLS. The genotype and allele frequencies did not differ significantly between two groups. CONCLUSIONS: These results suggest that DAT1 gene 40bp VNTR is not associated with the antipsychotic-induced RLS in schizophrenia. To confirm these results, larger-scale association study is needed in the future.
Antipsychotic Agents ; Base Pairing ; Dopamine ; Dopamine Plasma Membrane Transport Proteins ; Gene Frequency ; Genotype ; Humans ; Receptors, Dopamine ; Restless Legs Syndrome ; Schizophrenia ; Tandem Repeat Sequences

No abstract available.
Dermoid Cyst*

No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

Cardiac tamponade with pleural and pericardial effusion is a rare but life-threatening complication of umbilical venous catheterization in the newborn. It requires a timely diagnosis and urgent treatment, such as pericardiocentesis, to save lives of affected patients. Recently, we experienced a 7 day-old, very low birth weight infant, who developed a cardiac tamponade with pleural and pericardial effusions complicated by umbilical venous catheterization. The patient was successfully treated with pleural and pericardial drainages. Here, we report this case with a review of literature, since there has been no such previous case reported in Korea.
Cardiac Tamponade* ; Catheterization ; Catheters ; Diagnosis ; Humans ; Infant, Newborn* ; Infant, Very Low Birth Weight ; Korea ; Pericardial Effusion* ; Pericardiocentesis ; Pleural Effusion

Hemangiopericytoma was first described by Stout & Murray in 1942 and was an uncommon soft tissue tumor thought to be derived from vascular pericytes. Approximately 10-15% of the cases occur in children have a propensity to develop in the region of head, neck and lower extremities. We experienced a case of congenital hemangiopericytoma of small bowel in a male neonate who showed vomiting and abdorninal distension. We reported a case of congenital hemangiopericytoma of small bowel with brief review of related literature.
Child ; Head ; Hemangiopericytoma* ; Humans ; Infant, Newborn ; Intestinal Obstruction* ; Intestine, Small ; Lower Extremity ; Male ; Neck ; Pericytes ; Vomiting

OBJECTIVE: The aim of this study was to examine the psychosocial and obstetric predictors of depressive symptomatology at postpartum 4 weeks in Korea. METHODS: At their 1-week and 4-week postpartum visits, 61 postpartum women completed the Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and Symptom Check List-90-Revised (SCL-90-R). Data related to the psychiatric and obstetric characteristics, pregnancy and delivery related events were collected from the standardized medical records. 42 women with no history of pregnancy or delivery within the previous 6 months were selected as the control group. The postpartum group was divided into the depressive and non-depressive subgroups, according to their EPDS and BDI results at postpartum 4 weeks. RESULTS: Compared to the control group, the mean score of the BDI at postpartum 4 weeks was significantly higher in the postpartum group. The percentages of women having experienced severe emotional stress during pregnancy and of smokers and drinkers before pregnancy were significantly higher in the postpartum depressive subgroup (EPDS >or=10 and BDI >or=10) when compared to the postpartum non-depressive subgroup. The percentage of women having experienced depressive symptoms at postpartum 1 week was also significantly higher in the depressive subgroup. A depressive symptomatology at postpartum 1 week was identified as a significant risk factor for depressive symptoms at postpartum 4 weeks. CONCLUSION: The results of this study suggest that screening for depressive symptomatology in the immediate postpartum period might provide an effective means of detecting women at risk of developing postpartum depression in Korea. The finding that severe emotional stress experienced during pregnancy is associated with the development of postpartum depressive symptoms confirms the results of previous studies.
Anxiety ; Depression ; Depression, Postpartum ; Female ; Humans ; Korea ; Mass Screening ; Medical Records ; Postpartum Period* ; Pregnancy ; Risk Factors ; Stress, Psychological

PURPOSE: Recent reports pointed out that gonadotropin releasing hormone analogue (GnRHa) therapy alone is not so promising for improving adult height in precocious puberty. So, that we studied the growth promoting effect of combined therapy with GnRHa and growth hormone (GH) in early pubertal girls. METHODS: Twenty three early pubertal girls (9.73+/-1.59 yr) with predicted adult heights (PAH) below -2 standard deviation score (SDS) were included. They were divided into two groups as follows; Group I before menarche (n=19) and Group II after menarche (n=4). After combined therapy, various growth parameters were compared between two groups and between the before and after therapy. RESULTS: Between the two groups before therapy, chronologic age (CA), growth velocity (GV), body mass index (BMI), target height (TH), PAH and serum insulin-like growth factor binding protein-3 were not different, but BA, height and difference between bone age (BA) and CA were significantly higher and insulin-like growth factor-1 (IGF-1) was marginally higher in group II. After therapy, BA still remained higher in group II, but other parameters were not different. In both groups, after therapy, the difference between BA and CA, the ratio of BA over CA, and GV were significantly decreased, but PAH, height SDS and BMI were significantly increased. Regarding IGF-1 level, a significant increase was noted in group I, but not in group II. CONCLUSION: With combined therapy of GnRHa and GH, PAH in early pubertal girls might be improved significantly and even approach TH. Among them, those who were before menarche might have greater potential for the height gain than those after menarche in view of IGF-1 changes during therapy.
Adult* ; Body Mass Index ; Female* ; Gonadotropin-Releasing Hormone* ; Gonadotropins* ; Growth Hormone* ; Humans ; Insulin-Like Growth Factor I ; Menarche ; Puberty, Precocious

The objective of this study was to explore the psychosocial factors such as life events, coping styles and family relationships in middle-aged depressed women. This study was designed to compare how different variables relate to depression in two different test groups: a depressed patient group and a normal group. The Beck Depression Inventory(BDI), The Ways of Coping Checklist, Interpersonal Support Evaluation List(ISEL), Family Environment Scale were administered to 116 depressed patients and 113 normal persons between the ages of 35 and 64. The results were as follows 1) The highest stress was marital stress(n=42, 36.2%) in patient group and family stress(n=44, 38.9%) in normal group, respectively. 2) There were significant differences between patient group and normal group in BDI scores (t=15.94, p<.0001), lift events(t=4.73, p<.0001), active coping(t=6.29, p<.0001), social support(t=7.20, p<.0001), and family relationship(t=5.75, p<.0001) except for passive coping(t=0.93, p=.35). 3) In depressed patient group, BDI scores had a significantly positive correlation with the scores of the life event(r=.24, p<.01) and negative correlation with active coping(r= -.22, p<01), social support(r=-.35, p<.001) and family relationships(r=-.30, p<.001). 4) In depressed patient group, multiple regression analysis showed that social support(12.3%, beta=-.281, T=-3.162, P=.002), lift events(5.1%, beta=.279, T=3.195, F=.002), and active coping(3.5%, beta=-.204, T=-2.225, F=.028) had predictability on the BDI scores and the total predictability was 20.9%. 5) Stress experienced in family relationships were highest in life events and there was a lack of consistency(in the BDI scores ol the coping styles). Social support was the most important factor and there were no significant differences between the two groups in family relationships.
Checklist ; Depression ; Family Relations* ; Female ; Humans ; Psychology

No abstract available.
Hamartoma*