Objective:To investigate phobia of acute myocardial infarction(AMI)patients after percutaneous coronary intervention(PCI), analyze its latent profile and explore the influencing factors in different categories.Methods:Three hundreds and thirty-five AMI patients who received PCI in Emergency Department ofthe First Affiliated Hospital of Naval Medical University from January 2021 to June 2022 were selected by convenient sampling method and prospective research as the survey objects. The basic situation questionnaire, cardiophobia scale (TSK-SV Heart), Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), Connor Davidson Psychoelasticity Scale (CD-RISC) and Posttraumatic Stress Disorder Checklist (PCL) were selected to investigate them, and the linear growth model was selected to analyze the latent profile of postoperative phobia in AMI patients.Results:The score of post-operative phobia in AMI patients was (44.47 ± 7.25) points, and the latent profile analysis showed that AMI patients were classified into psychological type (156 cases, 46.57%), physiological type (164 cases, 48.96%) and severe type (15 cases, 4.47%). The severe phobia type was selected as the reference group, and multiple logistic regression analysis showed that compared with the severe phobia type, age, resilience, posttraumatic stress disorder (PTSD) and no or mild anxiety were significant influencing factors for phobia after PCI in patients with psychophobia type AMI ( P<0.05), while age and resilience were significant influencing factors for phobia after PCI in patients with physiological phobia type AMI ( P<0.05). Conclusions:Through latent profile analysis, there are three types of phobia in AMI patients after PCI: psychophobia, physiological phobia and severe phobia. Postoperative phobia is affected by psychological resilience, PTSD, age, chronic disease and depression. Therefore, targeted intervention should be carried out for AMI patients based on different characteristics of phobia after PCI to enhance their enthusiasm for rehabilitation.