1.Development of transcutaneous jaundice predictor for the neonates.
Pengzhi ZHU ; Hengxin YUAN ; Zhifeng TAN ; Guoping ZHU ; Yongju YI
Journal of Biomedical Engineering 2011;28(3):592-596
Neonatal jaundice is a common neonatal disease. Severe jaundices lead to kernicterus that affects intellectual development of infants or even causes death. Timely and early prediction is vital to the treatment and prevention. This paper presents a jaundice predictor, which uses C8051F020 as the core of single-chip microcomputer (SCM) system with prediction algorithms proven by a large number of clinical trials. The jaundice predictor can reduce the incidence rate of jaundice, alleviate the condition of infants with jaundice, improve the quality of perinatal, with predicting pathologic neonatal jaundice effectively and calling attention to the prophylactic treatment. In addition, compared with the existing transcutaneous jaundice meters, the new predictor has a smaller size, a lighter weight, more user-friendly, and easier to use by hand-holding.
Algorithms
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Bilirubin
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blood
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Equipment Design
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methods
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Humans
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Infant, Newborn
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Jaundice, Neonatal
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blood
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diagnosis
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Microcomputers
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Photometry
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methods
2.Platelets inventory changes and supply situation during COVID-19 epidemic
Xiaomin SU ; Xiaoli CAO ; Yuan ZHANG ; Linghao ZHANG ; Yali ZHANG ; Hengxin LI
Chinese Journal of Blood Transfusion 2022;35(10):1062-1064
【Objective】 To explore the impact of the COVID-19 epidemic on platelets supply management and its countermeasures. 【Methods】 Relevant data on platelets collection, supply, daily inventory and adjustment were collected through the blood information management system of our blood center after the outbreak of the epidemic in Xi′an (from December 9, 2021 to February 2, 2022), and then compared with the data during the corresponding period of last year (from December 9, 2020 to February 2, 2021). 【Results】 In this study, in the first half month of the epidemic, the collection and supply of platelets were slightly higher than the same period of the previous year. After the first-level response to the epidemic was initiated, the collection and issuing of platelets decreased significantly compared with the same period of the previous year. Half a month after the home isolation had been gradually lifted, the collection and issuing of platelets increased significantly as compared with the home isolation period. Otherwise, the collection and issuing of platelets had been increased as compared with the same period of the previous year. 【Conclusion】 After the outbreak of the epidemic, the timely adjustment of platelet collection strategy as well as the launch of emergency plan for platelets collection and supply during the first-level response to the epidemic effectively ensured the supply of clinical platelets in Xi′an during the period of home isolation.
3.SARS-CoV-2 seroprevalence among voluntary blood donors: A retrospective analysis in Xi′an
Yuan ZHANG ; Hua XU ; Jin DING ; Jing LAN ; Peng PENG ; Na LIU ; Jin WANG ; Lirong WANG ; Hengxin LI
Chinese Journal of Blood Transfusion 2021;34(12):1367-1369
【Objective】 To estimate the seroprevalence of SARS-CoV-2 infection among blood donors during the COVID-19 outbreak, in order to provide reference for formulating coping strategies. 【Methods】 A total of 3 623 samples of healthy blood donors in Xi′an from January 1 to June 14, 2020 were collected and tested by chemiluminescence microparticle immunoassays(CMIA). The correlation between the number of confirmed cases of COVID-19 in Xi′an and the monthly prevalence trend of SARS-CoV-2 antibody in Xi′an was also studied. 【Results】 Among the 3 623 blood donors, 3 were reactive by CMIA, with the seroprevalence rate of SARS-CoV-2 at 0.083%(95%CI: 0.00, 0.18). The earliest yielding of SARS-CoV-2 in Xi′an was in February 4, 2020. 【Conclusion】 The SARS-CoV-2 seroprevalence rate in Xi′an is low, which is in line with the local prevalence status. It is suggested that serological detection of blood donors is a way to monitor the prevalence of COVID-19.
4.The monitoring of adverse reactions to blood donation: a multi-center analysis
Aimin REN ; Bing JU ; Yuanyuan LIU ; Lin WANG ; Qin LI ; Xiaohua YUAN ; Ling HOU ; Wen LIU ; Honghua LIU ; Zhian ZHANG ; Haibo HAN ; Guiqi ZHAO ; Juan LI ; Tao QI ; Yufeng SUN ; Tao LI ; Tianning SI ; Yang ZHANG ; Hengxin LI
Chinese Journal of Blood Transfusion 2022;35(4):365-368
【Objective】 To investigate the establishment of multi-center haemovigilance (HV) and the monitoring of adverse reactions to blood donation (ARBD), in order to provide basis for the management of blood donors. 【Methods】 The operation of HV was investigated by questionnaire. The total number of blood donations (including plateletpheresis) and ARBD cases occurred in each blood center from 2014 to 2018 were analyzed. 【Results】 Among the 24 blood centers in this survey, only nine got HV operated. The incidence of ARBD of 19 blood centers that fulfilled the questionnaire was in the range of (0.003~1.151) %. The change trend of number and incidence of ARBD cases were indeterminate. 【Conclusion】 Most blood centers did not got HV established. The incidence of ARBD varied greatly and was indeterminate. The application of HV should be further improved to strengthen ARBD management.