1.Curative effect observation of pelvic rloor rehabilitation in the prevention of postoperative urinary retention for patients with gynecological malig-nancy
Zhuanxing SHEN ; Yuhong PAN ; Hengxi ZHOU ; Yufen LIN
China Modern Doctor 2014;(24):134-136
Objective To explore and observe the curative effect of pelvic floor rehabilitation in the prevention of post-operative urinary retention for patients with gynecological malignancy. Methods All 68 patients who received surgery of gynecological malignancy in 2012 were selected, and those receiving the surgery in the first half year were allocated into control group, and those receiving the surgery in the second half year were allocated into treatment group. The control group received regular treatment and nursing,while the treatment group,on the basis of the control group,be-gan to receive pelvic floor rehabilitation via neuromuscular biological electro-therapeutic apparatus 3 days before the removal of urinary catheter. Recovery of bladder functions was observed between two groups. Results The incidence of urinary retention in the treatment group was significantly lower than that in the control group,and the clinical effect in the treatment group was significantly better than that in the control group(P<0.05). Conclusion Pelvic floor rehabilita-tion in the prevention of postoperative urinary retention of gynecological malignancy has obvious curative effect.
2.Research progress of sarcopenia as a prognostic marker of genitourinary tumors
Jiajian YANG ; Qiuchen LIU ; Hengxi JIN ; Yuxin LIN ; Zheng ZHOU ; Jinxian PU
Chinese Journal of Urology 2022;43(5):389-392
Sarcopenia is observed to have age-related loss of skeletal muscle mass, muscle strength and physical performance, which can be an effective prognostic indicator for postoperative complications and poor survival outcomes in tumor patients. Sarcopenia could reflect tumor-host interactions and has the advantages in accuracy and generality compared with traditional predictors. This paper reviews the research progress of sarcopenia in predicting the prognosis of genitourinary tumors.
3.Changes in glial fibrillary acidic protein expression in different brain regions of rats with traumatic brain inj ury
Yan Cao ; Hengxi Li ; Jiali Li ; Tenghan Ling ; Aiping Yin ; Ying Zhou ; Li Yang ; Haiying Wu ; Ping Li
Acta Universitatis Medicinalis Anhui 2023;58(11):1828-1834, 1840
Objective :
To observe the expression of glial fibrillary acidic protein (GFAP) in the brain tissue of rats
with traumatic brain injury (TBI) and the differential changes between brain regions.
Methods :
The TBI model of rats was prepared by the modified Feeney free fall method , and it was randomly divided into the sham⁃operated qPCR were used to observe the morphological changes of activated astrocytes and the expression of GFAP in different brain regions after TBI.
Results :
Immunohistochemical staining showed that astrocytes were activated in all brain regions on the right side of TBI , and the only brain regions that spilled over to the contralateral side ( left) were cortical region 1 and midbrain regions. RT⁃qPCR results showed that GFAP mRNA was highly expressed in all brain regions on the right side of TBI , affecting the contralateral cortex and midbrain regions. Western blot results showed that GFAP protein was highly expressed in all brain regions on the right side of TBI , and it spread to the contralateral midbrain regions.
Conclusion
TBI can cause the activation of astrocytes and increase GFAP expression in the right brain regions , while also affecting the contralateral (left) cortex 1 and midbrain regions.