Objective To observe whether form-deprivation myopia/amblyopia could protect retinal microvascular system and postpone the development of diabetic retinopathy. Methods The form-deprivation myopia/amblyopia was established combined with hyperglycemia mouse model,and the retinal vascular endothelial cells and pericytes were counted. Results Endothelial cells/ pericytes ratio in hyperglyce-mia group is significantly lower than that in normal group and form-deprivation myopia/amblyopia combined with hyperglycemia group. Con-clusion Form-deprivation myopia/amblyopia combined with hyperglycemia mice have more pericytes than hyperglycemia mice.

Objective To explore the electroencephalogram (EEG)features and related factors of children with febrile convulsion (FC).Methods The clinical and EEG data of 168 FC children were retrospectively analyzed.Results Of 168 children with FC,the initial issuance of 147 patients aged 0.5 -3 years old (87.30%),>3 years was 21 cases (11.10%),3 -year -old children within the age of multiple febrile seizures;the abnormal rate of EEG≤3 years old febrile seizures was 25.20%,>3 years old abnormal rate was 75.00%,indicated that with age increased,higher rate of EEG abnormalities;abnormal rate of EEG in children ≥ 38.5℃ was 26.20%,EEG abnormal rate in children <38.5℃ was 66.00%,that was easy to cause convulsions when low heat.These were significantly different between the two groups (P <0.01).Abnormal EEG rate of attacks 1 -3 times was 37.91%,>3 times the EEG abnormality was 64.88%(P <0.05),indicated that repeated seizures,the likelihood of cerebral injury larger. Conclusion EEG abnormality rate is related with clinical features of the FC;FC EEG in children should be regular inspections to closely follow up observation of disease prognosis.

Objective To evaluate the efficacy of dexmedetomidine for improvement of postoperative analgesia with sufentanil in pediatric patients with a large area of burn after tangential excision and skin grafting.Methods Forty-two pediatric patients of both sexes with a large area of burn,of American Society of Anesthesiologists physical status Ⅱ or Ⅲ,aged 2-10 yr,weighing 13-36 kg,scheduled for elective tangential excision and skin grafting under combined propofol-remifentanil-sevoflurane anesthesia,were randomly divided into 2 groups (n=21 each) using a random number table:sufentanil group (group Suf) and dexmedetomidine plus sufentanil group (group Dex-Suf).The patient-controlled intravenous analgesia (PCIA) was used for postoperative analgesia.PCIA solution contained sufentanil 2 μg/kg and granisetron 100 μg/kg in 100 ml of normal saline in group Suf,and contained dexmedetomidine 2.5 μg/kg,sufentanil 1.5 μg/kg,and granisetron 100 μg/kg in 100 ml of normal saline in group Dex-Suf.The PCA pump was set up with a 0.5 ml bolus dose,a 15 min lockout interval and background infusion at a rate of 2 ml/h after a loading dose of sufentanil 0.1 μg/kg.When Faces Pain Scale score＞2,sufentanil 0.1 μg/kg was injected intravenously as rescue analgesic.The consumption of sufentanil was recorded within 48 h after operation.Ramsay sedation scores at static and dynamic (during dressing changes) conditions were assessed after operation.The parents' satisfaction,requirement for rescue analgesics and incidence of adverse reactions such as agitation,nausea and vomiting were recorded after operation.Results Compared with group Suf,Ramsay sedation scores at static and dynamic conditions and patients' satisfaction scores were significantly increased,and the consumption of sufentanil,requirement for rescue analgesics and incidence of agitation,nausea and vomiting were significantly decreased after operation in group Dex-Suf (P＜0.05).Conclusion Dexmedetomidine significantly improves postoperative intravenous analgesia with sufentanil in the pediatric patients with a large area of burn after tangential excision and skin grafting,and combination of dexmedetomidine and sufentanil is recommended for this type of pediatric patients.

Objective To compare the image quality and radiation dose of CTA of the kidney in patients using routine CT and the spectral imaging combination of different scanning protocols with the adaptive statistical iterative reconstruction 2.0 algorithm (ASIR 2.0). Methods A total of 90 patients who had undergone a CTA of the kidney were divided into three groups (A, B and C), with 30 patients in each group. Group A underwent a routine CT examination, and the scan parameters are:120 kVp, 30 to 650 mA, rotation time 0.5 s/r, scan FOV 50 cm × 50 cm;while groups B and C underwent spectral imaging protocol 1 and 2, the scan parameters of spectral imaging protocol 1 and 2 are:rapid dual kVp (80-140 kVp) switching in 0.25 ms, 375 mA and 360 mA, rotation time 0.7 s/r and 0.6 s/r, scan FOV 36 cm × 36 cm and 32 cm × 32 cm, respectively. All images were reconstructured using ASIR 2.0. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of all images were calculated when the kidney CTA was completed. Each subjective image evaluation used a 5-point scoring method and was conducted by two independent radiologists. The CT dose index (CTDIvol) and dose-length product (DLP) were recorded, and the mean value was calculated. The DLP was converted to the effective dose (ED). All data were compared with Kruskal-Wallis test and one-way ANOVA. Results The energy level of 49 to 56 keV was found to provide the best CNR for displaying CTA of the kidney. There were significant differences in CT values, noise, SNR, CNR and subjective score between groups B, C and A (P<0.05), and there was no significant differences in CT values, noise, SNR, CNR and subjective score between groups B and C (P>0.05). There were significant differences in ED among groups A, B and C (P<0.05), and the ED of groups A, B and C were (8.2±1.2), (5.2± 0.9) and (4.4 ± 0.7) mSv, respectively. Conclusion Spectral imaging with different scanning protocols can more effectively reduce the radiation dose than the routine CT scan mode for a kidney CTA while still maintaining diagnostic image quality, and protocol 2 of spectral imaging in our study is recommended.

QRS complex has its distinct characteristics as compared with other waves in Electrocardiogram (ECG). In this paper is introduced a kind of algorithm to identify the R waves, which combines forward-backward difference algorithm, half-wave width algorithm and R-R interval algorithm. The algorithm is simple and reliable. It is in possession of the ability of anti-interference such as baseline drifting, high P waves or high T waves, and severe high-frequency interference. The average accuracy for identification is higher than 99.5%. The results of the experiment and the analyses are also presented.
Algorithms ; Electrocardiography ; methods ; Humans ; Numerical Analysis, Computer-Assisted ; Signal Processing, Computer-Assisted

In this paper is presented the Lorenz plot, the qualitative analyses and quantitative parameters of the plot. The long axis vs short axis(LVS) parameter is given. Atrial Fibrillation Electrocardiogram (AF ECG) is compared with sinus ECG by use of Lorenz plot. Then the difference in their plots and the parameter of LVS is pointed out. Lorenz plot finding is useful for the AF disease in automatic diagnoses of ECG signals.
Atrial Fibrillation ; diagnosis ; physiopathology ; Automatic Data Processing ; methods ; Electrocardiography, Ambulatory ; methods ; statistics & numerical data ; Heart Rate ; Humans ; Signal Processing, Computer-Assisted