1.Cutaneous adverse drug reactions: A four-year audit from a district hospital in Johor, Malaysia
The Medical Journal of Malaysia 2018;73(6):397-399
Cutaneous adverse drug reactions (cADR) are common.
However, only very few audits reported the clinical
characteristics of cADR captured at district hospitals. We
performed a 4-year audit on cADR reported to the
Department of Pharmacy in Hospital Pakar Sultanah Fatimah
between May 2012 and March 2016. It showed that the main
adverse drug reaction (ADR) reporters were pharmacists
(84.9%) where the majority of the reactions were clinical
descriptions without dermatological diagnosis. Antibiotics
(46.4%) were the commonest culprit drug followed by
NSAIDs (22%). The most common reactions were immediate
reactions, i.e. urticaria and angioedema contributing 55.7%
of the cases; followed by maculopapular eruptions (41.8%).
There were only six cases (1%) of severe cADR reported in
this cohort. Reporting bias and the incomplete
dermatological diagnosis were the main limitation of the
reports.
2.A Clinical Evaluation of Esophageal Perforation.
Sun Ho JEON ; Tae Yeol JUNG ; Dong Sup SONG ; Hyuck KIM ; Shee Yeung HAHM ; Churl Bum LEE ; Jung Ho KANG ; Won Sang JUNG ; Young Hak KIM ; Heng Ok JEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(1):79-84
BACKGROUND: Esophageal perforation is an extremely lethal injury that requires careful management for survival. MATERIAL AND METHOD: We performed a retrospective clinical review of 14 patients treated for esophageal perforation at the Department of Thoracic and Cardiovascular Surgery hanyang University Hospital between July 1986 and August 1998. Cardiovascular Surgery Hanyang University Hospital between July 1986 and August 1998. RESULT: The ration between male and female patients was 12:2 and their ages ranged from 9 to 68 years( average: 446 years). Iatrogenic perforations were found in 6 patients(42.9%) spontaneous perforations in 3 patients(21.4%) traumatic perforations in 2 patients(14.3%) and caustic perforations foreign body origin and esophagel cancer in 1 patient (7.1%) each. Four of the patients(28.6%) had esophageal ruptures located cancer in 1 patient (7.1%) each. Four of the patients (28.6%) had esophageal ruptures located in the cervical esophagus and 10 patients (71.4%) in the thoracic esophagus, The most frequent location was in the mid third portion of the esophagus (35.7%) there were also 2 patients(14.3%) in the upper third portion and 3 patients(21.4%) in the lower third portion. Complications encountered included mediastinitis empyema or pleural effusion mediastinal or lung abscess sepsis and aspiration pneumonia. The most frequent complication that occurred was mediastinitis in 9 cases (57%) Three patients underwent conservative treatment. Among the patients who underwent surgical treatment 5 patients underwent primary closure 6 patients underwent open drainage and 2 patients underwent reconstrumction (1 patients had an initial primary closure and 1 patient had an initial open drainage procedure). The mortality rates for those with conservative and surgical treatment were 66.7% (2cases) and 9.1% (1 cases) respectively. CONCLUSIONS: Perforation of the esophagus although very rare has a high mortality rate and thus aggressive operative therapy is necessary.
Drainage
;
Empyema
;
Esophageal Perforation*
;
Esophagus
;
Female
;
Foreign Bodies
;
Humans
;
Lung Abscess
;
Male
;
Mediastinitis
;
Mortality
;
Pleural Effusion
;
Pneumonia, Aspiration
;
Retrospective Studies
;
Rupture
;
Sepsis
3.Colobronchial Fistula as a Late Complication of Esophagocologastrostomy.
Chul Burm LEE ; Sung Ho HAN ; Shee Young HAHM ; Heng Ok JEE ; Hyuk KIM ; Won Sang JUNG ; Young Hak KIM ; Jung Ho KANG
The Korean Journal of Thoracic and Cardiovascular Surgery 2002;35(1):77-81
We report a case of colobronchial fistula, which is an extremely rare complication of esophagocologastrostomy. A 53-year-old man developed recurrent respiratory symptoms 30 months after colon interposition for corrosive esophageal and gastric strictures. Chest radiographs and computed tomography showed an aspiration pneumonia and total atelectasis of the left lower lobe(LLL). Esophagoscopy and barium esophagogram revealed fistula between the colon just below the esophagocolostomy and superior segment of the LLL. The colobronchial fistulectomy and left lower lobe lobectomy were performed. This rare complication should be considered in patients who develop recurrent productive cough whenever they drink or eat something after esophagocologastrostomy.
Barium
;
Colon
;
Constriction, Pathologic
;
Cough
;
Esophagoscopy
;
Fistula*
;
Humans
;
Middle Aged
;
Pneumonia, Aspiration
;
Postoperative Complications
;
Pulmonary Atelectasis
;
Radiography, Thoracic
4.Colobronchial Fistula as a Late Complication of Esophagocologastrostomy.
Chul Burm LEE ; Sung Ho HAN ; Shee Young HAHM ; Heng Ok JEE ; Hyuk KIM ; Won Sang JUNG ; Young Hak KIM ; Jung Ho KANG
The Korean Journal of Thoracic and Cardiovascular Surgery 2002;35(1):77-81
We report a case of colobronchial fistula, which is an extremely rare complication of esophagocologastrostomy. A 53-year-old man developed recurrent respiratory symptoms 30 months after colon interposition for corrosive esophageal and gastric strictures. Chest radiographs and computed tomography showed an aspiration pneumonia and total atelectasis of the left lower lobe(LLL). Esophagoscopy and barium esophagogram revealed fistula between the colon just below the esophagocolostomy and superior segment of the LLL. The colobronchial fistulectomy and left lower lobe lobectomy were performed. This rare complication should be considered in patients who develop recurrent productive cough whenever they drink or eat something after esophagocologastrostomy.
Barium
;
Colon
;
Constriction, Pathologic
;
Cough
;
Esophagoscopy
;
Fistula*
;
Humans
;
Middle Aged
;
Pneumonia, Aspiration
;
Postoperative Complications
;
Pulmonary Atelectasis
;
Radiography, Thoracic
5.Malignant Fibrous Histocytoma Originating from the Chest Wall.
Churl Bum LEE ; Tae Yeol JUNG ; Shee Yeung HAHM ; Hyuck KIM ; Won Sang JUNG ; Young Hak KIM ; Jung Ho KANG ; Heng Ok JEE ; Yong Wook PARK
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(4):333-337
Malignant fibrous histiocytoma(MFH) is a deep-seated pleomorphic sarcoma, which occurs principally as a mass of the extremities, abdominal cavity, or retroperitoneum in adults. However, it only rarely occurs in the chest wall. An 85-year-old man had undeergone excision of a small mass on the right posterior chest wall under local anesthesia 14 months age. However, the lesion did not heal and the mass recurred. He was referred to our hospital after the mass had grown to a size of 10.5x8x4cm with a 3x3cm skin defect. Intraoperative frozen biopsy revealed MFH. An en-bloc wide resection and thin-thickness skin graft from his thigh were performed. Although distant metastasis to the lund developed 14 months later and the patient died 2 months later, there was no local recurrence. Thin-thickness skin graft is a simple method for a wide range skin defect, especially in the old age. He recovered in good condition without any physical disabilities.
Abdominal Cavity
;
Adult
;
Aged, 80 and over
;
Anesthesia, Local
;
Biopsy
;
Extremities
;
Humans
;
Neoplasm Metastasis
;
Recurrence
;
Sarcoma
;
Skin
;
Thigh
;
Thoracic Wall*
;
Thorax*
;
Transplants
6.Case Analysis of Pulmonary Sequestration.
Yang Bin JUN ; Sung Ho SHIN ; Tae Yeol JUNG ; Hyuck KIM ; Shee Yeung HAHM ; Churl Bum LEE ; Won Sang JUNG ; Young Hak KIM ; Jung Ho KANG ; Heng Ok JEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1998;31(12):1206-1211
BACKGROUND: Pulmonary sequestration is not common and it's diagnosis needs special care such as an aortogram ar tomography. MATERIAL AND METHOD: We have experienced 13 patients who had pulmonary sequestration from January 1990 to September 1997. RESULT: Six men and seven women were treated and their mean age was 25.8+/-14.3 years. Their chief complaints were coughing, chest pain, and no symptoms in decreasing order. There were nine intralobar (ILS) and three extralobar (ELS) pulmonary sequestrations and one patient had both. There was no preference in location of either left or right. They were mainly diagnosed by aortography and their feeding arteries commonly originated from the lower thoracic aorta. The patients with ILS were treated by lobectomy and those with ELS by sequestrectomy. CONCLUSION: to treat pulmonary sequestration properhy, aortogram or chest CT is warranted to iidenty the abnormal origin of feeding artery.
Aorta, Thoracic
;
Aortography
;
Arteries
;
Bronchopulmonary Sequestration*
;
Chest Pain
;
Cough
;
Diagnosis
;
Female
;
Humans
;
Male
;
Tomography, X-Ray Computed
7.A case of arrhythmogenic right ventricular cardiomyopathy with right ventricle thrombus: A case report
Qin Jian Low ; Carwen Siaw ; Seng Wee Cheo ; Heng Shee Kim ; Cheang Leng Benjamin Leo ; Norliza Binti Othman ; Chuey Yan Lee
The Medical Journal of Malaysia 2020;75(4):452-454
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is
a rare inherited cardiomyopathy characterised by right
ventricular dysfunction, ventricular arrhythmias and increased
risk of sudden cardiac death. Due to the replacement of
myocardium with fibro-fatty and fibrous tissue, patients with
ARVC are prone to develop ventricular tachycardia.
Histologically, it is often reported as the ‘triangle of dysplasia’
involving the inflow tract, outflow tract and apex of the right
ventricle.2 We describe a 20-years-old patient who collapsed
during a futsal match and was subsequently diagnosed to have
ARVC with a right ventricular thrombus from cardiac
magnetic resonance imaging.