Three cases of polycystic kidney were treated with conservative therapy. Of three cases one showed normal blood pressure and improved digestive disturbance after the therapy. i. e., direct aspiration of the kidney. Direct aspiration method is thought to be desirable one before the kidney operation is performed.
Blood Pressure ; Kidney ; Polycystic Kidney Diseases*

Exteriorization of the ureteral stump in nephrectomy was devised by Dr. William Mayo and was clinically applied for the treatment of renal tuberculosis by Dr. John K. Lattimer. The method was used in eighteen cases of nephrectomy with successful results at our clinic during the past two years. Ureteral Exteriorization is considered one of the most reasonable methods of preventing possible local infection at the operative wound during and after nephrectomy of a severely infected kidney. We believe that instillation or continuous irrigation of antibacterial solutions through the exteriorized ureteral stump is a simple and useful procedure for the treatment of residual infection of the urinary tract after nephrectomy.
Kidney ; Nephrectomy* ; Tuberculosis, Renal ; Ureter* ; Urinary Tract ; Wounds and Injuries

The author has observed 17 cases of the penis carcinoma is 5 years during the period from April 1954 to March 1959. 1. Their average age was 50.1 years ranging from 36 to 66 years. 2. Thirteen of 17 cases were hard workers. Average duration between the onset of the penis cancer and patients visit to hospital was about 11 months. 3. Five cases of them had suffered from venereal disease, and all of them had long prepuce or complete phimosis. 4. In 9 cases the cancer was originated at the glans penis, in 4 cases at the inner surface area of the prepuce, in 3 cases at the sulcus cornalis and one at the outer surface of the prepuce. 5. Ten cases of them had the swelling of inguinal lymphnode. Grossly, lesions were composed of 5 ulcerative form, 5 infiltrative form, 4 nodular form and 3 papillary form. 6. Microscopical findings in 9 cases showed squamous cell carcinoma in 8 cases and one case of malignant melanoma. 7. In regards to the treatment of penis cancer. the most desirable method was to prevent it. Circumcision in early age and keeping genitalia clean may contribute to the prevention.
Carcinoma, Squamous Cell ; Circumcision, Male ; Female ; Genitalia ; Humans ; Male ; Melanoma ; Penile Neoplasms ; Penis* ; Phimosis ; Sexually Transmitted Diseases ; Ulcer

PURPOSE: Bacterial meningitis in neonates and young infants is one of the most serious conditions that can lead to severe neurological sequelae despite the appropriate treatment. This study aimed at evaluating the clinical manifestations and treatment outcomes in patients under the age of three months, who had been diagnosed with bacterial meningitis. METHODS: A total of twelve patients with bacterial meningitis under the age of three months from January 1997 to June 2010 were retrospectively evaluated through a review of their medical records. Patients who showed positive culture results were included in the study. RESULTS: A total of 12 patients (6 males and 6 females, mean age 44.2+/-30.0 days) were enrolled in the study. All patients had fever upon admission. But most of them were unremarkable upon physical examination (75%). Streptococcus agalactiae was the most common organism cultured from CSF (7cases; 58.3%). Six cases showed positive results on CSF culture as well as on blood culture. Cefotaxime and ampicilin/sulbactam or cefotaxime and ampicilin were given as initial treatment with a mean treatment duration of 15.1+/-6.0 days. Neurological complications and sequelae included subdural effusion and hearing disturbance in two cases (16.7%). Nine cases (75%) showed excellent outcomes without neurological deficits, and none were left with a severe degree of sequelae. CONCLUSION: The study showed that neonates or young infants with bacterial meningitis almost always present with fever and that S. agalactiae was the most common causative organism. In addition, the final outcome for these patients may be improved with early and appropriate treatment.
Cefotaxime ; Female ; Fever ; Hearing ; Humans ; Infant ; Infant, Newborn ; Male ; Medical Records ; Meningitis, Bacterial ; Physical Examination ; Retrospective Studies ; Streptococcus agalactiae ; Subdural Effusion ; Treatment Outcome

PURPOSE: It is now well established that infection and inflammation play an important role in the pathogenesis of ischemic brain damage. The loss of neutrophils from systemic circulation is an associated finding in injury mediated by granulocyte. Periventricular leukomalacia(PVL) caused by ischemia is the principal form of brain injury in premature infants. This study was conducted to evaluate whether the low neutrophil count is associated with periventricular leukomalacia(PVL) in premature infants. METHODS: Retrospective review of medical records was undertaken. Subjects were premature infants with a birth weight of less than 1,500 gm, admitted to the Neonatal Intensive Care Unit of Kyungpook University Hospital. A complete blood count of peripheral blood was done within the 1st hour of life. Neutropenia was defined as absolute neutrophil count <1,500/mm3, PVL as increased periven tricular echodensities followed by cyst formation on ultrasonography or corresponding signs on brain MRI. RESULTS: Thirteen infants out of a total population of 37 revealed neutropenia. Respiratory distress syndrome and requirement for respiratory support were not different between infants with neutropenia(neutropenia group) and infants without neutropenia(control group). Intraventricular hemorrhage (IVH) and grade 3 and 4 IVH were more frequent in neutropenia group(P<0.05). There was no statistically significant increase of PVL in neutropenia group. The neutrophil count was 18,760.0+/-10,266.1/mm3, 7,272.0+/-7,435.0/mm3 infants with PVL and 11,131.7+/-3,386.5/mm3, 2,407.5+/-1,933.1/mm3 in infants without PVL, respectively. The frequency of mechanical ventilation and artificial surfactant therapy was higher in infants with PVL compared with infants without PVL, but statistical analysis was not performed due to small number of subjects. CONCLUSION: A low number of neutrophils in the systemic circulation was not associated with an increased risk of PVL in premature infants.
Birth Weight ; Blood Cell Count ; Brain ; Brain Injuries ; Granulocytes ; Gyeongsangbuk-do ; Hemorrhage ; Humans ; Infant ; Infant, Newborn* ; Infant, Premature ; Inflammation ; Intensive Care, Neonatal ; Ischemia ; Leukomalacia, Periventricular* ; Magnetic Resonance Imaging ; Medical Records ; Neutropenia ; Neutrophils* ; Respiration, Artificial ; Retrospective Studies ; Ultrasonography

The Dowling-Meara type of epidermolysis bullosa simplex is a rare genodermatosis transmitted by autosomal dominant pattern. It starts during the first 3 months of life and is characterized by generalized bullae in a herpetiform pattern. We report two cases of Dowling-Meara type of epidermolysis bullosa simplex. The first case is an 18-year-old male patient who showed bullae in a herpetiform arrangement on the dorsa of both hands, forearms, and trunk, hyperkeratosis on the palms and soles, postinflammatory hypo- and hyperpigmentations, and dystrophy of finger and toe nails. The second case is a 1-month-old boy who showed multiple bullae in a herpetiform and confluent arrangement scattered on the whole body, particularly on the dorsa of both feet and hands. Microscopically and electro-microscopically, two cases all showed intraepidermal blisters formed within the basal keratinocyte in association with clumping of the tonofilaments and cytolysis of the basal cells.
Adolescent ; Blister ; Epidermolysis Bullosa Simplex* ; Epidermolysis Bullosa* ; Fingers ; Foot ; Forearm ; Hand ; Humans ; Infant, Newborn ; Intermediate Filaments ; Keratinocytes ; Male ; Toes

PURPOSE: This study was undertaken to determine whether any features of apoptosis would occur in the established model of cerebral hypoxia-ischemia in neonatal rats. It was also undertaken to evaluate the effect of post-insult hyperoxia on hypoxic ischemic cerebral injury. METHODS: Seven-day-old neonatal rats underwent unilateral carotid artery dissection followed by 2 hours of hypoxia. To this end rat pups, allocated into 2 groups, were resuscitated with high concentration O2(>FiO2 95%) or room air for a 1-hour period. All of them were killed at 3 days after the above procedures. Their brains were perfusion fixed and removed to examine tissue damage by light microscope and apoptosis by terminal deoxynucleotidyl transferase mediated dUTP- biotin nick end labeling(TUNEL) reactivity. RESULTS: The result demonstrates that hypoxia-ischemia model induces tissue damage and TUNEL. Post-insult exposure to high reactivity concentration O2 does not aggravate hypoxic-ischemic cerebral injury 3 days after the insult but increases TUNEL reactivity in injured tissue. CONCLUSIONS: These findings suggest that many cells die by apoptosis following hypoxia-ischemia in neonatal brain and resuscitation with high concentration O2 seems to provide an adverse effect over a brain injury by induction of apoptosis.
Animals ; Anoxia ; Apoptosis ; Biotin ; Brain Injuries* ; Brain* ; Carotid Arteries ; DNA Nucleotidylexotransferase ; Hyperoxia ; Hypoxia-Ischemia, Brain ; In Situ Nick-End Labeling ; Ischemia ; Models, Animal* ; Oxygen* ; Perfusion ; Rats* ; Resuscitation*

Since sclerosing hemangioma of the lung was first described by Liebow and Hubbell in 1956, there have been several reports on cases occurring as a solitary nodule; however, sclerosing hemangiomas occurring as multiple nodules are extremely rare. The histogenesis of this tumor remains controversial and there are several hypotheses of the etiology. Three separate nodules were found in a 57-year-old housewife, one found in the right middle lobe, one in the apicoposterior segment of the left upper lobe, and one in the superior segment of the left lower lobe. The only symptom or sign presented was a dry cough. Apicoposterior segmentectomy of the left upper lobe and wedge resection of the superior segment of the left lower lobe were performed. The postoperative course was uneventful and the patient was discharged on the postoperative 15th day.
Cough ; Hemangioma ; Histiocytoma, Benign Fibrous* ; Humans ; Lung Neoplasms ; Lung* ; Mastectomy, Segmental ; Middle Aged ; Pulmonary Sclerosing Hemangioma

Eosinophilic gastroenteritis (EGE) is a disorder characterized by eosinophilic infiltration of the bowel wall and various gastrointestinal (GI) manifestations. This study aimed to evaluate the characteristics of EGE in infants and children. A total of 22 patients were diagnosed with histologic EGE (hEGE) or possible EGE (pEGE). Serum specific IgE levels, peripheral eosinophil counts, and endoscopic biopsies were carried out. In the hEGE group (n = 13), initial symptoms included hematemesis, abdominal pain, and vomiting. Three of the subjects had normal endoscopic findings. Eight patients were categorized into the infant group and 5 into the child group. All patients in the infant group showed clinical improvement after switching from cow's milk feeding to special formula or breast feeding. The infant group showed a higher eosinophil count in the gastric mucosal biopsy than the child group. In the pEGE group (n = 9) initial symptoms included hematemesis, abdominal pain, and vomiting. Seven patients in this group showed a good response to treatment with restriction of the suspected foods and/or the administration of ketotifen. Both hEGE and pEGE groups showed clinical improvement after restriction of suspected foods in the majority of cases and also showed a similar clinical course. EGE should be considered in the differential diagnosis of patients with chronic abdominal pain, vomiting, and hematemesis of unknown cause. The infant group may have a better prognosis than the child group if treated properly.
Child ; Child, Preschool ; Diagnosis, Differential ; Disease Progression ; Endoscopy, Gastrointestinal/*methods ; Enteritis/*pathology/*therapy ; Eosinophilia/*pathology/*therapy ; Female ; Gastritis/*pathology/*therapy ; Humans ; Infant ; Infant, Newborn ; Intestinal Mucosa/*pathology ; Male ; Republic of Korea ; Treatment Outcome

A persistent left superior vena cava draining into the coronary sinus is the most benign and widely encountered abnormality and can easily be explained embryologically as the persistence of the usual pattern of vnous circulation in the embryo,. However a persistent left superior vena cava draining into the left atrium with absent right superior vena cava is an extremely rare anomaly. We report this situation in an infant with tetralogy of Fallot. The most common approach has traditionally been intraatrial baffle repair to create a tunnel to the right atrium or rerouting of the left superior vena cava flow by directly anastomosing the left superior vena cava to the right atrium In the present study the left superior vena cava was transposed to the left pulmonary artery after the correction of tetralogy of Fallot. The most common approach has traditionally been intraatrial baffle repair to create a tunnel to the right atrium or rerouting of the left superior vena cava flow by directly anastomosing the left superior vena cava to the right atrium. In the present study the left superior vena cava was transposed to the left pulmonary artery after the correction of tetralogy of Fallot.
Coronary Sinus ; Embryonic Structures ; Heart Atria* ; Humans ; Infant ; Pulmonary Artery ; Tetralogy of Fallot* ; Vena Cava, Superior*