Hemorrhagic Fever, Ebola ; diagnosis ; drug therapy ; epidemiology ; prevention & control ; Humans

The Ebola virus belongs to the Filovirus family, which causes Ebola hemorrhagic fever (mortality, 25%-90%). An outbreak of infection by the Ebola virus is sweeping across West Africa, leading to high mortality and worldwide panic. The Ebola virus has caused a serious threat to public health, so intensive scientific studies have been carried out. Several vaccines (e.g., rVSV-ZEBOV, ChAd3-ZEBOV) have been put into clinical trials and antiviral drugs (e.g., TKM-Ebola, ZMAPP) have been administered in the emergency setting to patients infected by the Ebola virus. Here, recent advances in vaccines and drugs against the Ebola virus are reviewed.
Animals ; Antiviral Agents ; administration & dosage ; Ebola Vaccines ; administration & dosage ; genetics ; immunology ; Ebolavirus ; drug effects ; genetics ; immunology ; physiology ; Hemorrhagic Fever, Ebola ; drug therapy ; prevention & control ; virology ; Humans

No abstract available.
Antiviral Agents/therapeutic use ; Hemorrhagic Fever, Ebola/drug therapy/*prevention & control/virology ; Humans ; Protective Devices ; Vaccines/immunology

No abstract available.
Antiviral Agents/therapeutic use ; Hemorrhagic Fever, Ebola/drug therapy/*prevention & control/virology ; Humans ; Protective Devices ; Vaccines/immunology