1.Rectally administered misoprostol in the prevention of pospartum hemorrhage due to uterine inertia
Ho Chi Minh city Medical Association 2003;8(3):130-132
Hemorrhage;Postpartum Period; Uterine Inertia; prevention & control;
777 postpartum women were studied at Tu Du Obstetric and Gynecology Hospital, HCM city. Rectal misoprostol of 400mg was well tolerated and effective to reduce hemorrhage amount and to shorten the 3rd phase of labor just after the delivery. The procedure is simple with low cost, easy to use in remote areas of the country contributing in lowering obstetric accidents and mortality.
Hemorrhage
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Postpartum Period
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Uterine Inertia
;
prevention & control
2.Five Cases of Polypectomy using Endoscopic " O " -ring Ligation.
Jung Myung CHUNG ; Sang Hyuk LEE ; Sang Yong SEOL ; Dae Sik KOO ; Kyung Seok OH ; Hyen Jung JANG ; Chan Hwan KIM
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):442-449
Endoscopic polypectomy was firstly introduced by Tsuneoka in 1969, and till now this method has been widely used for the treatment of benign and malignant polyps with the advent of technical improvement. This method is a very important modality as secondary prevention of malignancy because polyps in gastraintestinal tract are now being considered as precancerous lesion. Polypectomy with snare and electrocautery is mainly used for pedunclated polyps (eg. Yamada Class III, IV), but sessile polyps pose technical difficulty and occasionally cause serious gastrointestinal hemorrhage when resection margin adjacent polyp base. We performed polypectomy with "O"-ring used in endocopic variceal ligation (EVL) to make sessile polyp as semipedunclated form, and also to control bleeding, and then successfully remove it with conventional snare polypectomy. We report these 5 cases with the review of the literature.
Electrocoagulation
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Gastrointestinal Hemorrhage
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Hemorrhage
;
Ligation*
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Polyps
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Secondary Prevention
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SNARE Proteins
5.Aspirin Usage Based on Evidence for the Prevention of Cardio-Cerebrovascular Disease.
Young Sang KIM ; Kyoung Kon KIM ; In Cheol HWANG
Korean Journal of Family Medicine 2009;30(4):249-260
Aspirin is well known for its central role in preventing cardio cerebrovascular diseases as an antiplatelet agent. However besides its favorable effects, one must also be fully aware of its side effects such as gastrointestinal complications or cerebral hemorrhage. Particularly when prescribing to Koreans, one must be highly cautious, considering the higher prevalence of helicobacter pylori infection and the contribution of hemorrhagic stroke as a major part of cerebral disease in Korean. Currently the guideline for secondary prevention of cardio cerebrovascular diseases is relatively well established, while the consensus for primary prevention is still controversial. The purpose of this paper would be to summarize the evidence of aspirin usage in preventing cardio cerebrovascular diseases, examine the additional factors one must consider, and help primary physician prescribing aspirin appropriately.
Aspirin
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Cerebral Hemorrhage
;
Consensus
;
Helicobacter pylori
;
Prevalence
;
Primary Prevention
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Secondary Prevention
;
Stroke
6.Recent trends of study on esophageal variceal bleeding.
Liu-fang CHENG ; Chang-zheng LI
Chinese Medical Journal 2010;123(18):2499-2501
7.Trauma-induced pulmonary thromboembolism: What's update?
Chinese Journal of Traumatology 2022;25(2):67-76
Trauma-induced pulmonary thromboembolism is the second leading cause of death in severe trauma patients. Primary fibrinolytic hyperactivity combined with hemorrhage and consequential hypercoagulability in severe trauma patients create a huge challenge for clinicians. It is crucial to ensure a safe anticoagulant therapy for trauma patients, but a series of clinical issues need to be answered first, for example, what are the risk factors for traumatic venous thromboembolism? How to assess and determine the status of coagulation dysfunction of patients? When is the optimal timing to initiate pharmacologic prophylaxis for venous thromboembolism? What types of prophylactic agents should be used? How to manage the anticoagulation-related hemorrhage and to determine the optimal timing of restarting chemoprophylaxis? The present review attempts to answer the above questions.
Anticoagulants/adverse effects*
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Hemorrhage
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Humans
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Pulmonary Embolism/prevention & control*
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Risk Factors
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Venous Thromboembolism/prevention & control*
8.Aspirin for Primary Prevention of Cardiovascular Disease
Ji Hye KIM ; Min Jung SHIM ; So Young LEE ; Jisu OH ; Sang Hoon KIM
Journal of Lipid and Atherosclerosis 2019;8(2):162-172
Aspirin has been used for decades for the primary and secondary prevention of cardiovascular disease (CVD). The effect of aspirin in secondary prevention is well-known but is still debatable for primary prevention. Despite the controversy, aspirin is believed to have a beneficial effect in primary prevention and has been widely used. However, whether the doubts concerning the wide use of aspirin are correct has resulted in the publication of data from several large clinical trials recently. There are several clinical guidelines from various international organizations on the use of aspirin for the primary prevention of CVD, and they offer some conflicting recommendations. A reduction in the overall incidence of CVD with the development of modern prevention therapies has weakened the impact of aspirin in primary prevention. Large randomized clinical trials have found decreased or no difference in CVD events but a significant increase in the risk of bleeding. Taking aspirin for the primary prevention of CVD is no longer recommended, especially for patients who have a low to moderate risk. An assessment of the balance between the benefits and risks of aspirin use should be considered.
Aspirin
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Cardiovascular Diseases
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Hemorrhage
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Humans
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Incidence
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Primary Prevention
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Publications
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Risk Assessment
;
Secondary Prevention
9.When less is more: can we abandon prophylactic platelet transfusion in Dengue fever?
Changa KURUKULARATNE ; Frederico DIMATATAC ; Diana Lt TEO ; David C LYE ; Yee Sin LEO
Annals of the Academy of Medicine, Singapore 2011;40(12):539-545
Dengue fever (DF) has several hematological manifestations including thrombocytopenia and increased bleeding risk. Prophylactic platelet transfusion-in the absence of major bleeding-is utilized in DF with thrombocytopenia with the intention of preventing hemorrhagic complications. However, prophylactic platelet transfusion in DF is neither standardized nor supported by clinical evidence. We conclude that risks, costs and poor resource utilization associated with prophylactic platelet transfusion in DF far outweigh any potential hematological benefit, and as such, should not constitute routine clinical practice.
Dengue
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complications
;
therapy
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Hemorrhage
;
etiology
;
prevention & control
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Humans
;
Platelet Transfusion
;
adverse effects
;
economics
;
Thrombocytopenia
;
etiology
;
prevention & control