Hemorrhage ; pathology ; Humans ; Thrombocytopenia ; pathology

We expirenced multiple hepatocellular adenomatosis, which was proved by pathology, in 38 years old man who had no prior history of predisposing factors. The radiologic findings were different by the size of tumor mass and intratumoral hemorrhage. Ultrasound demonstrated inhomogeneous hyperechoic large mass in segment 5 of right lobe and hyperechoic or isoechoic multiple small nodules in right lobe. Computed tomography demonstrated low density mass without contrast enhacement. Central high density is noted in hemorrhagic portion. Magnetic resonance T1-weighted image demonstrated high signal intensity in mass and hemorrhagic portion. T2-weighted image demonstrated slightly high signal intensity in mass portion, high signal intensity in hemorrhagic portionand double-layered peripheral rim. Gradient echo image well demonstrated inhomogenesity of mass.
Causality ; Hemorrhage ; Pathology ; Ultrasonography

No abstract available.
Cerebral Hemorrhage* ; Pathology*

Organizing hematomas are rare benign tumors and appear as masses that are composed of neovascularization with organizing fibrotic tissue in a hematoma. Although histologically benign, this condition may be clinically progressive. Radiological findings can range from a benign appearance to a more aggressive process, including bony erosion. Organizing hematoma of the maxillary sinus is a rare clinical disease. To our knowledge, only a few cases have previously been published, and most were without bleeding history and disorders. Until now, all of the reports about this lesion have discussed the clinical course, and no previous report has closely considered pathologic findings and pathogenesis. We report three cases of organizing hematoma of the maxillary sinus presenting with an enlarging maxillary sinus mass.
Hematoma* ; Hemorrhage ; Maxillary Sinus* ; Pathology

Fracture of the penis a rare condition, properly defined as a tear of the fibrous sheath of the corpora cavernosa occurred by direct blow or bending of the penis during erection. Its characteristic pathology is a tear in the tunica albuginea of the corpora cavernosa with hemorrhage, hematoma formation and distortion of the organ. Herein we reported a case of fracture of the penis, occurred by rolling in bed during erection in 26 years old man and repaired surgically.
Adult ; Hematoma ; Hemorrhage ; Humans ; Male ; Pathology ; Penis*

Autopsy by forensic pathologist is a main mean currently to determine the cause of sudden unexpected death. Retinal examination is important but seldom performed during a forensic autopsy for various reasons. The value of retina examination has not been recognized. With invention of ophthalmic endoscopy and its subsequent application in postmortem retina examination, it has proved to be useful adjunct to determine the cause of death and to estimate the postmortem interval.
Adult ; Autopsy ; Cause of Death ; Craniocerebral Trauma/pathology* ; Decompression Sickness/pathology* ; Female ; Forensic Pathology/methods* ; Humans ; Male ; Middle Aged ; Ophthalmoscopy ; Retina/pathology* ; Subarachnoid Hemorrhage/pathology* ; Syndrome ; Vitreous Hemorrhage/pathology*

Unexpectedly high rates of venous thromboembolic events (VTE) induced by highly effective immune modulating drugs thalidomide and lenalidomide for treatment of multiple myeloma have focused attention on the incidence and underlying pathophysiology of VTE in patients with plasma cell dyscrasias, and on thromboprophylaxis approaches. While bleeding complications are relatively uncommon in the patients with lymphoproliferative disorders, acquired von Willebrand syndrome, typically occurring in the patients with monoclonal gammopathy of unknown significance, and acquired coagulopathies associated with primary amyloidosis can present with haemorrhagic complications and both are challenges to the management. This review highlights these important haemostasis-related complications of plasma cell dyscrasias and provides an overview of other uncommon bleeding and thrombotic events that can affect diagnosis and therapeutic management of clonal plasma cell disorders. Due to the infrequency of most these haemostasis complications, available information is typically based on retrospective cases or series analysis.
Hemorrhage ; etiology ; pathology ; therapy ; Humans ; Paraproteinemias ; complications ; pathology ; Thrombosis ; etiology ; pathology ; prevention & control

OBJECTIVETo study the clinical characteristics and pathogenesis of hematidrosis.

METHODSDetailed clinical manifestations and natural history of a patient with hematidrosis were presented. A series of laboratory examinations were performed, and skin pathohistologic features and ultra microscopic structures were observed.

RESULTSThe episodes of skin bleeding occurred on any site of the body spontaneously and promptly. The skin surface bloody extravasation has identical cell components as that of peripheral blood. All the results of laboratory tests were normal except a positive Trousseau's test. Skin pathohistological study revealed some intradermal bleeding and emphraxised capillaries. No abnormality was found in sweat glands, hair follicles and sebaceous glands.

CONCLUSIONThe pathological basis for hematidrosis might be a distinctive vasculitis.

Child ; Female ; Hemorrhage ; pathology ; Humans ; Skin ; blood supply ; pathology ; Skin Diseases ; pathology

OBJECTIVETo investigate the histopathological changes in the liver and other organs after impact injury.

METHODSThe rabbits were impacted with a BIM-IV biological impacting machine at the xiphoid process. The severity of liver injury was graded and scored through gross anatomy. At the same time, the pathological changes in the liver, heart, and lung were observed by light and electron microscopes.

RESULTSLight microscopy showed that the pathological changes in the liver were: 1) loss of normal structure, hemorrhage and distortion of hepatic lobules; 2) cloudy swelling, degeneration, vacuolation and necrosis of liver cells; 3) infiltration of neutrophils. The lungs were injured and there were liver cell emboli in the small pulmonary arteries. Electron microscopy showed that the ultrastructure of the liver cells was severely damaged and the cells had significant features of necrosis.

CONCLUSIONSThe major pathomorphological changes in the liver after impact injury are hemorrhage and necrosis. They may be complicated by exfoliation of liver cells to hepatic sinusoids. These cells circulate with the blood to form emboli in the pulmonary blood vessels.

Animals ; Female ; Hemorrhage ; pathology ; Liver ; injuries ; pathology ; Male ; Myocardium ; pathology ; Necrosis ; Rabbits

Interference with visual pathways is usually not caused by intracranial aneurysms. Aneurysms of the anterior communicating artery rarely produce visual symptoms and signs in spite of their proximity to the visual pathways. The reason may be that these aneurysms rupture and present with subarachnoid hemorrhage before becoming large enough to exert significant pressure on the chiasm or optic nerves. The visual symptoms would be presented as visual field defect or impaired vision. These can be explained as the result of direct compression of the optic pathways, ischemic changes in the visual pathways caused by severe vasospasm after subarachnoid hemorrhage, or intraocular pathology such as retinal hemorrhage. 2 cases of anterior communicating artery aneurysms associated with visual symptoms are presented with a brief review of literatures.
Aneurysm ; Arteries ; Intracranial Aneurysm* ; Optic Nerve ; Pathology ; Retinal Hemorrhage ; Rupture ; Subarachnoid Hemorrhage ; Visual Fields ; Visual Pathways