Aspergillus species are primarily pulmonary pathogens but can involve extra-pulmonary organs by angioinvasive properties. Isolated renal aspergillosis is extremely rare even among the immunocompromised patients. Recently, we experienced a case of isolated renal aspergillosis presenting gross hematuria and renal mass-like lesion in a patient with acute myelocytic leukemia, who was treated with systemic amphotericin B and oral itraconazole after nephrectomy. To our knowledge, this is the first report of isolated renal aspergillosis in a patient with acute leukemia receiving chemotherapy. Here, we report this case with a review of literature.
Amphotericin B ; Aspergillosis* ; Aspergillus ; Drug Therapy ; Hematuria ; Humans ; Immunocompromised Host ; Itraconazole ; Leukemia ; Leukemia, Myeloid, Acute* ; Nephrectomy

A 30 years old male suffering from renal pain, hematuria and frequency of urination, was found to have horseshoe kidney with renal tuberculosis. The diagnosis was made through urinalysis, intra-venous pyelography and retrograde pyelography. This is a report of the good results gained by partial nephrectomy and antituberculous chemotherapy. It was compared with several literary reviews.
Adult ; Diagnosis ; Drug Therapy ; Hematuria ; Humans ; Kidney* ; Male ; Nephrectomy ; Tuberculosis* ; Tuberculosis, Renal ; Urinalysis ; Urination ; Urography

During 5 years, from January 1976 to December 1980, clinical observation on management of ureteral stones was made on 169 admitted patients with ureter stones. Following results were obtained. 1) Among total 1054 in-patients, 169 cases (16.0%) had ureteral stones, and male to female ratio was 2 : 1. 2) Patients with 20-40 of his age was half. 3) On seasonal distribution, it was most prevalent on Summer. 4) 113 cases were located on lower ureter, and laterality was even. 5) Most common symptoms were renal colic and hematuria (91.8%) 6) Ureterolithotomy was done in 127 cases. In 86 cases of lower ureter stones, less than 1cm in size. conservative fluid therapy and cystoscopic extraction was successful in 44 cases. 7) Post-operative complications were urinary leaking (16 cages), wound infection(12 cases), hematuria (3 cases), ureteral stricture (1 case), and pyelonephritis (1 case).
Constriction, Pathologic ; Female ; Fluid Therapy ; Hematuria ; Humans ; Male ; Pyelonephritis ; Renal Colic ; Seasons ; Ureter* ; Wounds and Injuries

A clinical observation was made on the patients with Wilms' tumor admitted to the Yonsei University Hospital during the period from January, 1974 to December, 1981. 1. Age distribution was between 5 months to 76/12 years, the highest incidence rate was in the age group of 12 to 24 months. 2. Mass in abdomen was the most common symptom occurred in 63.2%, gross hematuria in 31.6%, abdominal distention and anorexia in 20.1% each and the others. 3. Left to right ratio was 1.7:1 and simultaneous bilateral tumor was not observed. 4. On I.V.P., 47.4% of cases revealed nonfunctioning kidney. Right renal deformity or displacement was observed in 42.1%, calcification in the tumor mass in 10.5%. 5. On treatment of Wilms' tumor, surgery, irradiation and chemotherapy was performed on 11 cases, surgery and post-op, chemotherapy 4 cases, surgery only 2 cases and irradiation and chemotherapy only 1 case each.
Abdomen ; Age Distribution ; Anorexia ; Congenital Abnormalities ; Drug Therapy ; Hematuria ; Humans ; Incidence ; Kidney ; Wilms Tumor*

Primary or metastatic malignant melanoma can mimic benign blue nevus in rare cases, making the diagnosis challenging. Herein, we report an exceptionally rare case of blue nevus-like melanoma and its blue nevus-like metastasis which was detected by catheterized urine cytology. The patient presented with blue-colored papuloplaques on his temple which were diagnosed as blue nevus-like melanoma on punch biopsies. While he was admitted for administration of chemotherapy, hematuria was detected. Catheterized urine cytology revealed singly scattered oval to spindle-shaped pigmented cells with a moderate degree of variation in shape and size. Many of them had small nuclei with indiscernible to inconspicuous nucleoli while only a few cells showed nuclear enlargement and nuclear hyperchromasia, which could be diagnostic pitfalls. Most of the cells on the smear were positive for HMB45 immunostaining, which confirmed the diagnosis of metastatic blue nevus-like melanoma. To the best of our knowledge, the present case is the first report describing cytomorphologic findings of blue nevus-like metastasis of melanoma in the urine specimen.
Biopsy ; Catheters* ; Diagnosis ; Drug Therapy ; Hematuria ; Humans ; Melanoma* ; Neoplasm Metastasis ; Nevus, Blue

Type IV collagen is a component of the extracellular matrix in the basement membrane. Abnormal secretion or assembly of type IV collagen may lead to kidney lesions resulting in numerous nephropathy symptoms, e.g., Alport syndrome, thin basement membrane nephropathy, and focal segmental glomerulosclerosis. Treatment for type IV collagen-related nephropathy includes drugs, kidney transplantation, gene and cell therapy. However, drugs are not always effective, and kidney transplantation is hindered by the shortage of donors. Moreover, basement membrane nephritis often occurs after kidney transplantation. Therefore, gene and cell therapy probably is the most promising treatment for type IV collagen related nephropathies.
Cell- and Tissue-Based Therapy ; Collagen Type IV ; Glomerulosclerosis, Focal Segmental ; Hematuria ; Humans ; Nephritis, Hereditary

OBJECTIVETo systematically evaluate the effects of finasteride on hematuria associated with benign prostatic hyperplasia (BPH).

METHODSWe electronically searched MEDLINE (December 1966-April 2009), EMBASE (December 1974-April 2009), The Cochrane Library (Issue 1, 2009), CNKI (December 1994-April 2009), VIP (December 1989-April 2009) and CBM (December 1978-April 2009) , and handsearched several relevant journals as well. Randomized controlled trials were assessed with the methods recommended by the Cochrane Collaboration. The data were screened and systematically analyzed by at least two reviewers independently using the RevMan 5.0 software.

RESULTSCompared with the placebo control group, the finasteride group showed a significantly decreased incidence of hematuria during the 12 months follow-up period (OR 0.11, 95% CI: 0.06-0.21, P < 0.05).

CONCLUSIONFinasteride has desirable therapeutic and preventive effects on BPH-associated hematuria. More well-designed multicentered randomized controlled trials of large sample size are invited to provide further evidence for this conclusion.

Finasteride ; therapeutic use ; Hematuria ; drug therapy ; etiology ; prevention & control ; Humans ; Male ; Prostatic Hyperplasia ; complications ; drug therapy ; Randomized Controlled Trials as Topic

Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment.
Acute Kidney Injury ; Erythrocytes ; Fibrosis ; Glomerulonephritis, IGA ; Hematuria ; Hepatitis B ; Humans ; Immunoglobulin A ; Immunoglobulins ; Lamivudine ; Necrosis ; Renal Insufficiency ; Renal Replacement Therapy

Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment.
Acute Kidney Injury ; Erythrocytes ; Fibrosis ; Glomerulonephritis, IGA ; Hematuria ; Hepatitis B ; Humans ; Immunoglobulin A ; Immunoglobulins ; Lamivudine ; Necrosis ; Renal Insufficiency ; Renal Replacement Therapy

Although it has been estimated that from 90 to 95% of all vesical neoplasms are of epithelial origin, and about 80% or more of carcinomas of the bladder are of transitional cell type, pratically all of the other constituents of the bladder have been known to give rise to benign and malignant tumors. A clinical observation was made on the non-transitional cell bladder tumors of the patients in the department of urology, Seoul National University Hospital during the period from 1966 to April, 1976. The following results were obtained: 1) During the period, 3699 patients were hospitalized, there were 293 cases of bladder tumors giving a rate of 7.9%. 2) Among 187 cases of bladder tumors there were 15 cases of non-transitional bladder tumors with a rate of 8%. 3) Age distribution was between 28 and 76 years. 4) Following symptoms could be found, hematuria in 93%, frequency 40%, dysuria 33% and other symptoms. 5) Squamous cell carcinoma was observed on 8 cases (4.3%), adenocarcinoma 3(1. 6%), metastatic carcinoma 2 (1.0%), malignant lymphoma 1 (0.5%). 6) Segmental resection was performed in 5 cases, total cystectomy 4, TUC 2 cases. Radiation and chemotherapy were combined in special cases. 7) 3 patients with squamous cell carcinoma died within 1 year after treatment.
Adenocarcinoma ; Age Distribution ; Carcinoma, Squamous Cell ; Cystectomy ; Drug Therapy ; Dysuria ; Hematuria ; Humans ; Lymphoma ; Seoul ; Urinary Bladder Neoplasms* ; Urinary Bladder* ; Urology