Cardiac Tamponade ; etiology ; Heart Neoplasms ; complications ; Hemangiosarcoma ; complications ; Humans ; Pericardial Effusion

Atrial Fibrillation ; Cardiac Tamponade ; etiology ; Heart Atria ; Heart Neoplasms ; complications ; Hemangiosarcoma ; complications ; Humans

Spontaneous pneumothorax is a rare manifestation of metastatic lung cancers and described in advanced diseases or during cytotoxic chemotherapy which is manifested by sudden onset of dyspnea. The cause or mechanism of spontaneous pneumothorax has been unknown, as well as the association with site of metastases or type of cancers or side effect of chemotherapeutic drugs has been reported rarely. A 68-yr-old man underwent excision of angiosarcoma of the scalp. Chest radiography did not show any evidence of possible metastatic lung lesion at that time. Therefore, systemic doxorubicin and dacarbazine were given. After nineteen days of chemotherapy, he developed a bilateral spontaneous pneumothorax and palpable cervical lymph nodes. Both parietal and visceral pleura were intact and showed no evidence of metastatic and pathologic lesions on thoracoscopic evaluation. The patient managed with bilateral tube thoracostomy and both lungs were expanded. Lymph nodes became unpalpable during three cycles of the paclitaxel and doxorubicin, however, bilateral lung metastases were developed and progressed despite chemotherapy. The patient died due to respiratory failure after five months. This report underlines that spontaneous pneumothorax can occur as the first manifestation of metastatic angiosarcoma even if imaging studies do not show of a metastatic lesion.
Aged ; Antigens, CD31/metabolism ; Antineoplastic Combined Chemotherapy Protocols ; Fatal Outcome ; Hemangiosarcoma/complications* ; Hemangiosarcoma/pathology ; Human ; Lung Neoplasms/complications* ; Lung Neoplasms/secondary ; Male ; Pneumothorax/etiology* ; Scalp/pathology* ; Skin Neoplasms/complications* ; Skin Neoplasms/pathology

Hemangiosarcoma ; complications ; diagnosis ; pathology ; Humans ; Lung Neoplasms ; complications ; diagnosis ; pathology ; Male ; Sarcoma ; complications ; diagnosis ; pathology ; Shoulder Pain ; diagnosis ; etiology ; Young Adult

Angiosarcoma is a rare malignant tumor which occurs frequently in the skin and soft subcutis. Moreover, primary gastrointestinal angiosarcomas are very rare. This tumor manifests as non-specific symptoms such as gastrointestinal bleeding, abdominal pain and nausea. The diagnosis is often made at an advanced stage. Surgery, chemotherapy and radiotherapy are the mainstay of treatment. However, the prognosis is very poor. We report a case of primary angiosarcoma of the small intestine presenting as recurrent gastrointestinal bleeding. A 54-year-old man was admitted with recurrent gastrointestinal bleeding. An abdominal CT scan revealed an ileo-ileal intussusception. Segmental resection was performed with ileo-ileal anastomosis. The ileal mass was diagnosed as angiosarcoma on immunohistochemical stain. He received 3 cycles of chemotherapy, but died 5 months after the diagnosis.
English Abstract ; Gastrointestinal Hemorrhage/*etiology ; Hemangiosarcoma/complications/*diagnosis/pathology ; Humans ; Intestinal Neoplasms/complications/*diagnosis/pathology ; *Intestine, Small/pathology ; Male ; Middle Aged ; Recurrence

Aged, 80 and over ; Disseminated Intravascular Coagulation ; complications ; Forehead ; physiopathology ; Hemangioma, Capillary ; complications ; Hemangiosarcoma ; etiology ; physiopathology ; Humans ; Kasabach-Merritt Syndrome ; Male ; Scalp ; physiopathology

Several months after left radical mastectomy without irradiation therapy for breast cancer, a 74-year-old woman developed severe edema on the homolateral arm extending to the axilla. Ten years later, purplish to brownish blotch and nodules accompanied with heating sensation and pain appeared and increased in size gradually on the left forearm. The patient was treated by irradiation therapy under the clinical and histopathologic diagnosis of Stewart-Treves syndrome and almost all of the skin lesions and symptoms disappeared after irradiation of 6450 rads.
Aged ; Arm ; Breast Neoplasms/*surgery ; Female ; Hemangiosarcoma/*etiology/pathology/radiotherapy ; Humans ; Lymphedema/*complications ; Mastectomy, Radical/*adverse effects ; Skin Neoplasms/*etiology/pathology/radiotherapy

A 29-year-old pregnant woman with recurrent pericardial effusion and a cardiac tumor, diagnosed as an angiosarcoma, was treated with surgical resection of the tumor followed by radiotherapy. Immediately after completion of radiotherapy, she developed bilateral breast masses, which were also confirmed as angiosarcomas. We thought this might be the first case of bilateral angiosarcoma of the breast metastasizing to heart mimicking a primary cardiac angiosarcoma, although we could not conclude with certainty that angiosarcoma of the heart was not the primary site.
Adult ; Biopsy ; Breast Neoplasms/*pathology ; Cardiac Surgical Procedures ; Female ; Heart Neoplasms/complications/*pathology/surgery ; Hemangiosarcoma/*pathology ; Humans ; Magnetic Resonance Imaging ; Pericardial Effusion/etiology ; Positron-Emission Tomography ; Pregnancy ; Radiotherapy, Adjuvant ; Tomography, X-Ray Computed