1.Subarachnoid disseminative hemangiopericytoma of the spinal cord.
Guo-zhong LIN ; Zhen-yu WANG ; Zhen-dong LI ; Yan-feng ZHONG ; Lei-ming WANG
Chinese Medical Journal 2010;123(11):1485-1488
Adult
;
Hemangiopericytoma
;
diagnosis
;
Humans
;
Male
;
Spinal Cord
;
pathology
2.Nasal hemangiopericytoma: a case report.
Yong Koo PARK ; Jae Hoon PARK ; Youn Wha KIM ; Ju Hie LEE ; Moon Ho YANG
Journal of Korean Medical Science 1990;5(3):173-178
A case of rare intranasal hemangiopericytoma in a 68-year-old male was reported with typical histological and ultrastructural findings. The lesion clinically resembled a nasal polyp. The experience in the present case raised the need for differential diagnoses of vascularised spindle cell tumors and of traditional hemangiopericytoma in soft tissue.
Aged
;
Diagnosis, Differential
;
Hemangiopericytoma/diagnosis/*pathology
;
Humans
;
Male
;
Nasal Cavity
;
Nasal Polyps/diagnosis/*pathology
;
Nose Neoplasms/diagnosis/*pathology
3.MR Findings of Vascular Masses of the Head and Neck: Differential Diagnosis and Interventional Treatment Planning.
Hyo Heon KIM ; Ik Won KANG ; Kil Woo LEE ; Hong Kil SUH ; Shin Young CHO ; Ku Sun KIM ; Young Soo NO ; Suk Joon OH
Journal of the Korean Radiological Society 1995;33(2):205-211
PURPOSE: To characterize the MR findings for a differential diagnosis and to make a plan for treatment by interventional technique of the vascular masses with/without hypertrophic feeding vessels of the head and neck. SUBJCETS AND METHODS: Seven patients with vascular masses of the head and neck proved by pathology, angiography, clinical findings were included. Vascular masses included 4 venous malformations, a capillary hemangioma, and a hemangiopericytoma, a hemangioma combined with arteriovenous malformation. 7 patients had MR studies with 1.0T and 1.5T using routine TI-, T2- weighted spin echo sequences, and contrast enhancement. 4 MR angiography, 3 inversion recovery, and 6 contrast angiography were studied from 7 patients RESULTS: All vascular masses demonstrated higher than muscle signal intensity on Tl-weighted images, bright signal intensity on T2-weighted images, and prominent enhancement, except AV hemangioma combined with prominent arteriovenous malformation on postcontrast scan. Three hemangiomas demonstrated distinct serpiginous signal voids. Venous malformations demonstrated venous lakes seen as homogenous regions of high signal intensity and phleboliths seen as low signal foci on images. Inversion recovery was the best pulse sequence for evaluation of the extent of lesion. CONCLUSION: MR findings of the vascular masses of the head and neck are useful in delineating the extent of the disease, differentiating venous malformation or cavernous hemangioma from other hemangiomatous lesions including hypertrophic feeding vessels, and making a plan for treatment by interventional technique also.
Angiography
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Arteriovenous Malformations
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Diagnosis, Differential*
;
Head*
;
Hemangioma
;
Hemangioma, Capillary
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Hemangioma, Cavernous
;
Hemangiopericytoma
;
Humans
;
Lakes
;
Neck*
;
Pathology
4.Clinical analysis of 5 cases with hemangiopericytoma in nasal cavity and paranasal sinuses.
Gang XU ; Gang HE ; Bing LIU ; Zhongming XU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(5):314-317
OBJECTIVE:
To improve the accuracy of diagnosis and treatment efficacy of hemangiopericytoma in nasal cavity and paranasal sinuses.
METHOD:
The clinical and pathological data of 5 cases with hemangiopericytoma in nasal cavity and paranasal sinuses verified by pathology were analyzed retrospectively.
RESULT:
Computed tomography scan revealed vascular in 5 cases. On CT scan, hemangiopericytoma generally appeared to be a uniform high density mass with obvious enhancement upon injection of contrast material. In pathological examination, there were plentiful capillaries which were like tree branch. The normal endocytes were in the inner wall of the vessel. The round, oval and spear-like pericytes scattered around the vessel. The split phase of the nucleus could be found in the tumor cell. All cases underwent surgical resection and were proved by pathological examination. The clinical data showed that the prognosis of sinonasal hemangiopericytoma was closely related to its histological grade. The recur rate in highly malignant hemangiopericytoma was obviously higher than that in middle and low malignant tumor. The rate of misdiagnosis was 80%.
CONCLUSION
Hemangiopericytoma is a potentially malignant tumor. Medical imaging can help to demonstrate the site, configuration, and characteristics of the tumors and contribute to the treatment. But there are not characteristic medical features. The final diagnosis must depend on the closely related to its pathological grade. The doctor should pay attention to the description of histological pathology. All the patients must be followed up carefully.
Adult
;
Aged
;
Female
;
Follow-Up Studies
;
Hemangiopericytoma
;
diagnosis
;
pathology
;
Humans
;
Male
;
Middle Aged
;
Nasal Cavity
;
pathology
;
Paranasal Sinus Neoplasms
;
diagnosis
;
pathology
;
Retrospective Studies
;
Young Adult
5.Hemangiopericytoma in nasal cavity: a case report.
Honghai HU ; Qifeng SHI ; Jidong CHEN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(9):853-854
We report a case of a 46 year old female patient with nasal hemangiopericytoma. She complained of left nasal congestion, pus snot for 10 years, sometimes with left nasal bleeding. Physical examination: in the left nasal tract saw red soft neoplasm, roughness surface, easy bleeding when touched. Sinus CT shows: bilateral maxillary sinus, ethmoid sinus, sphenoid sinus and the left posterior nasal cavity lesions, considering inflammation with the formation of polyps, tumor not excluded. The left nasal cavity neoplasm biopsy shows: hemangioma of left nasal cavity. After admission in general anesthesia, we do transnasal endoscopic sinus openning operation and the left nasal cavity neoplasm resection. Postoperative pathological examination shows: the left nasal cavity hemangiopericytoma. Immunohistochemical showed: Vimentin(+), Smooth muscle actin(+), Desmin(-), endothelial cells CD31(-) and CD34(-). No postoperative radiotherapy or chemotherapy, no tumor recurrence. After one year of follow-up, the contact was lost.
Biopsy
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Endoscopy
;
Epistaxis
;
Ethmoid Sinus
;
pathology
;
Female
;
Hemangiopericytoma
;
diagnosis
;
pathology
;
Humans
;
Inflammation
;
pathology
;
Middle Aged
;
Nasal Cavity
;
pathology
;
Nasal Polyps
;
pathology
;
Neoplasm Recurrence, Local
;
Nose Neoplasms
;
diagnosis
;
pathology
;
Sphenoid Sinus
;
pathology
6.Solitary Fibrous Tumours/Hemangiopericytomas of the Maters(Meninx):A Clinicopathologic Analysis.
Ran ZHU ; Jun Yi PANG ; Chun Ming YANG ; Zhen HUO
Acta Academiae Medicinae Sinicae 2019;41(4):512-516
To study the clinicopathologic characteristics,immunohistochemical features,differential diagnosis,and prognosis of solitary fibrous tumours(SFT)/hemangiopericytomas(HPC)in the maters(meninx). Methods A series of 7 cases previously diagnosed as SFT/HPC at the Department of Pathology,Peking Union Medical College Hospital,during the period from 2008 to 2018 were analyzed for clinical data,histopathology,and immunohistochemical findings.The patients were followed up and the relevant literatures were reviewed. Results These seven patients included two males and 5 females aged 22 to 77 years(mean,49 years).Headache was the most common symptom.The magnetic resonance imaging of SFT/HPC showed irregularly contoured masses and dural tail sign was observed at the periphery of the lesion in 4 cases.The major axis of the tumor ranged from 1.8 cm to 10 cm(mean,4 cm).The tumors were located in the mater in 6 cases and in the spinal meninx in 1 case.The tumors were surgically removed in all cases.Under light microscope,the tumors were formed by long round,oval or spindle cells,with rich branching vascular pattern and varying quantity of collagenous fibers bands in both sparse areas and dense areas.According the WHO classification,2 cases were in WHO grade Ⅰ,2 cases in WHO grade Ⅱ,and 3 cases in WHO grade Ⅲ.Immunohistochemistry of the paraffin-embedded tissues in all cases showed positive immunoreativity for CD34 and vimentin in all seven cases,along with positive signal transducer and activator of transcription 6 in 4 cases,negative epithelial membrane antigen and S-100 in 7 cases,and negative progestational hormone and somatostatin receptor 2 in 6 cases.The Ki-67 index ranged from 1% to 15%.Five patients with follow-up data(including 1 current case)were alive,while 2 patients were lost to follow-up. Conclusions The SFT/HPC are rare in the maters(meninx)and is clinically difficult to be differentiated from other meningioma.The combination of CD34 and signal transducer and activator of transcription 6 helps to diagnose this disease.
Adult
;
Aged
;
Antigens, CD34
;
metabolism
;
Diagnosis, Differential
;
Female
;
Hemangiopericytoma
;
diagnosis
;
pathology
;
Humans
;
Immunohistochemistry
;
Male
;
Meninges
;
pathology
;
Middle Aged
;
Prognosis
;
STAT6 Transcription Factor
;
metabolism
;
Solitary Fibrous Tumors
;
diagnosis
;
pathology
;
Young Adult
7.Solitary fibrous tumor of kidney: report of a case.
Jianbing ZHANG ; Mei JIN ; Tao ZHU ; Xiaozhe SHI ; Jihong SUN
Chinese Journal of Pathology 2014;43(1):44-45
Adult
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Angiomyolipoma
;
pathology
;
Antigens, CD34
;
metabolism
;
Diagnosis, Differential
;
Female
;
Hemangiopericytoma
;
pathology
;
Humans
;
Kidney Neoplasms
;
metabolism
;
pathology
;
surgery
;
Nephrectomy
;
Sarcoma, Synovial
;
pathology
;
Solitary Fibrous Tumors
;
metabolism
;
pathology
;
surgery
;
Vimentin
;
metabolism
8.Clinicopathologic characteristics of myopericytoma.
Yan-bo ZHU ; Qing WEI ; Fei YUAN ; Xiao-long JIN
Chinese Journal of Pathology 2005;34(5):279-282
OBJECTIVETo investigate the clinicopathologic characteristics and differential diagnosis of myopericytoma.
METHODSSix cases of myopericytomas were analyzed by light microscopy and immunohistochemistry (LSAB detection method).
RESULTSTumors from 3 females and 3 males were found on the extremities and chest wall. The ages of these 6 patients ranged from 16 to 58 years. Histologically, all tumors were unencapsulated. The neoplastic cells were oval to spindle shaped with eosinophilic cytoplasm, had a myoid appearance and showd areas of concentric perivascular proliferation around lesional blood vessels which were present with focal myxoid stroma. Morphologically in some cases the tumor overlap myofibroma, hemangiopericytoma or glomus tumor. One tumor was located entirely within the lumen of a vein. In another case, the tumor displayed cellular pleomorphism, mitotic activity, necrosis should be diagnosed as malignant myopericytoma. The neoplastic cells were positive for SMA and negative for CD31, CD34, S-100, and CK.
CONCLUSIONSMyopericytoma is composed of oval to spindle shaped myoid cells with a striking tendeny for concentric perivascular growth. These cells differentiate towards perivascular myoid cells or myopericytes. Extremely rare malignant myopericytoma exist.
Actins ; metabolism ; Adolescent ; Adult ; Diagnosis, Differential ; Female ; Glomus Tumor ; metabolism ; pathology ; Hemangiopericytoma ; metabolism ; pathology ; surgery ; Humans ; Male ; Middle Aged ; Myofibroma ; metabolism ; pathology ; Neoplasms, Vascular Tissue ; metabolism ; pathology ; Soft Tissue Neoplasms ; metabolism ; pathology ; surgery ; Vimentin ; metabolism
9.Extraskeletal mesenchymal chondrosarcoma of nasal cavity: report of a case.
Jing LIU ; Hua-xiong GUO ; Lu YUAN ; Zheng-yuan HE
Chinese Journal of Pathology 2009;38(3):204-205
12E7 Antigen
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Adult
;
Antigens, CD
;
metabolism
;
Cell Adhesion Molecules
;
metabolism
;
Chondrosarcoma, Mesenchymal
;
metabolism
;
pathology
;
surgery
;
Diagnosis, Differential
;
Hemangiopericytoma
;
pathology
;
Humans
;
Lymphoma
;
pathology
;
Male
;
Nasal Cavity
;
Neuroectodermal Tumors, Primitive
;
pathology
;
Nose Neoplasms
;
metabolism
;
pathology
;
surgery
;
Vimentin
;
metabolism
;
Young Adult
10.Primary hemangiopericytoma of bone: report of a case.
Zhi-ming JIANG ; Hui-zhen ZHANG ; Jin HUANG ; Juan ZHOU
Chinese Journal of Pathology 2012;41(2):139-139
Adolescent
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Antigens, CD34
;
metabolism
;
Bone Neoplasms
;
diagnostic imaging
;
metabolism
;
pathology
;
Chondrosarcoma, Mesenchymal
;
metabolism
;
pathology
;
Diagnosis, Differential
;
Hemangiopericytoma
;
diagnostic imaging
;
metabolism
;
pathology
;
Humans
;
Male
;
Platelet Endothelial Cell Adhesion Molecule-1
;
metabolism
;
Sarcoma, Synovial
;
metabolism
;
pathology
;
Tomography, X-Ray Computed
;
Vimentin
;
metabolism