3.Infantile hemangioendothelioma of the liver: a case report.
Yeon Lim SUH ; Kyung Ja CHO ; Je G CHI ; Kwi Won PARK
Journal of Korean Medical Science 1987;2(3):195-200
A case of type 1 infantile hemangioendothelioma of the liver in a 3 month old male infant who had an abdominal mass incidentally noted at 40 days of age, is described. Grossly, the tumor showed a well circumscribed, pinkish gray and gelatinous mass with areas of central necrosis, multifocal thrombi and hemorrhages, and small cysts. Microscopically, the lesion consisted of numerous vascular channels of various size lined by a single layer of flat or plump endothelial cells. Areas of infarction, thrombosis and calcification, and formation of cavernous hemangiomatous foci were also noted in the lesion. Ultrastructurally, the cells had the characteristics of endothelium, including basal lamina, pinocytic vesicles, and Weibel-Palade bodies. Factor VIII-associated antigen was demonstrated in the tumor cells.
Hemangioendothelioma/*pathology/surgery
;
Humans
;
Infant
;
Liver Neoplasms/*pathology/surgery
;
Male
4.Primary cardiac hemangioendothelioma: a case report.
Li-feng WANG ; Ming LIU ; Hong ZHU ; Wei HAN ; Cheng-yi HU ; Ji-ping QI ; Huan-lin MEI ; Re-le GE ; Min ZHOU
Chinese Medical Journal 2006;119(11):966-968
7.Hemangioendothelioma of the sphenoid bone: a case report.
Mee JOO ; Ghi Jai LEE ; Young Cho KOH ; Yong Koo PARK
Journal of Korean Medical Science 2001;16(2):241-244
Hemangioendothelioma is borderline or intermediate type of vascular neoplasm. Hemangioendothelioma is rare lesion that constitutes less than 0.5% of the malignant tumors of bone. We present a case of low-grade hemagioendothelioma of the skull in a 29-yr-old woman. She had pain, diplopia and exophthalmos of the left eye. Radiographic images showed a relatively well-demarcated, expansile osteolytic lesion with irregularly thickened trabeculae and calcifications in the left greater wing of sphenoid bone. Histologically, the tumor was an infiltrative vasoformative lesion. The vessels are generally well-formed with open or compressed lumina surrounded by endothelial cells showing mild atypia. It lacked frequent mitotic figures and severe atypia. Although excessive bleeding occurred during the operation, the mass was totally resected. Postoperative radiation was not necessary. She is free of disease and well 6 months postoperatively.
Adult
;
Bone Neoplasms/*pathology/radiography
;
Female
;
Hemangioendothelioma/*pathology/radiography
;
Human
;
Pregnancy
;
Sphenoid Bone/*pathology
10.Diagnostic value of contrast-enhanced ultrasound in hepatic epithelioid hemangioendothelioma.
Ya Dan XU ; Han Tao WANG ; Yu Li ZHU ; Yi DONG ; Wei Bin ZHANG ; Wen Ping WANG ; Feng MAO ; Zheng Biao JI
Chinese Journal of Hepatology 2023;31(6):589-593
Objective: To investigate the features of contrast-enhanced ultrasound (CEUS) in hepatic epithelioid hemangioendothelioma (HEHE) in order to improve the preoperative diagnosis rate. Methods: CEUS images of 32 pathologically-proven cases of hepatic epithelioid hemangioendothelioma from January 2004 to August 2021 were collected. Lesions were analyzed to observe the features of enhancement mode, enhancement intensity, and distinct enhancement phases. Results: Among the 32 cases, one had a solitary lesion, 29 had multiple lesions, and two had diffuse-type lesions. Contrast-enhanced ultrasound revealed a total of 42 lesions in 32 cases. In terms of arterial phase enhancement, 18 lesions had overall enhancement, six lesions had uneven dendritic enhancement, 16 lesions had rim-like enhancement, and two lesions had just slight peripheral spot enhancement around the lesions. Among the three cases, there were multiple lesions that had overall enhancement and ring enhancement. In terms of the enhancement phase, 20 lesions showed "fast progression", 20 lesions showed "same progression", and two lesions showed "slow progression". During the late arterial or early portal venous phases with rapid washout, all lesions manifested as hypoechoic. With peaked enhanced intensity, 11 lesions had a lower enhancement intensity than the surrounding normal liver parenchyma; 11 lesions had the same enhancement degree as the surrounding normal liver parenchyma; and 20 lesions had a higher enhancement degree than the surrounding normal liver parenchyma. All 16 ring-enhancing lesions had marked hyperenhancement. In the typical enhancing lesions, four showed hyperenhancement, five showed low enhancement, and nine showed isoenhancement. In the dendrite-enhancing lesions, there were two isoenhancing and four hypoenhancing. Contrast-enhanced ultrasound delineated the boundaries of all lesions more clearly than two-dimensional ultrasound. Conclusion: Contrast-enhanced ultrasound has certain value in the diagnosis of hepatic epithelioid hemangioendothelioma.
Humans
;
Hemangioendothelioma, Epithelioid/pathology*
;
Contrast Media
;
Retrospective Studies
;
Liver Neoplasms/pathology*
;
Portal Vein/pathology*
;
Ultrasonography