1.The application of contrast enhanced ultrasonography combined with circulating leucocyte for acute coronary syndrome
Hejin LÜ ; Zhen LIU ; Shaonan LI ; Daihong WU ; Pinan CHEN
The Journal of Practical Medicine 2019;35(4):620-625
Objective Investigation of the significance for applying the percentage of neutrophils, neutrophil to lymphocyte ratio combined with contrast enhanced ultrasonography in the diagnose of coronary artery disease through examining the percentage of neutrophils, neutrophil to lymphocyte ratio on peripheral blood. Methods 130 patients with acute coronary syndrome (ACS group) , 90 patients with stable angina (SAP group) and 50 nonCAD patients (control group were observed. The neutrophils counts of all the patients were detected and Neut%, NLR were calculated; all the patients were asked to examine enhanced carotid contrast echocardiography. The plaque enhancement (DE) , and luminal enhancement ratio (Ratio) were recorded. The differences in neut%, NLR and CEUS were compared among the three groups. The Pearson correlation analysis was used to analyze the correlation between Ratio and Neut%, NLR. Multivariate logistic regression analysis was used to evaluate the predictive value of Neut%, NLR and CEUS for ACS. Results (1) The value of Neut%, NLR of the peripheral blood, DE, and Ratio in both ACS group and SAP group were higher than those in control group, and the value of ACS group was higher than that in SAP group (P < 0.05 or P < 0.01); (2) The analysis of Linear correlation showed that the ratio of CEUS in ACS patients was positively correlated with Neut% (r = 0.422, P = 0.001) and NLR (r = 0.407, P = 0.001). (3) The ROC results showed that circulating Neut%, NLR and DE, Ratio play a significant role in the diagnose of unstable plague in CAD patients; (4) Multivariate logistic regression analysis showed that Neut%, NLR, DE, Ratio were independent indicators of the ACS patients (P< 0.05 or P < 0.01).Conclusions Contrast enhanced carotid examination combined with leukocyte analysis on peripheral blood were useful to detect plaque instability and inflammatory response in CAD patients, and it also provide lots of objective evidence for predicting and intervening unstable plaque in CAD patients.
2.Clinical application effects of thoracoscopic pulmonary resection assisted with magnetic anchor technique
Xiaopeng YAN ; Yixing LI ; Peinan LIU ; Hanzhi ZHANG ; Nanzheng CHEN ; Jia ZHANG ; Xingang YANG ; Xiaolong HUANG ; Zhidong WANG ; Jiangtao YOU ; Shuangyan LI ; Aihua SHI ; Feng MA ; Junke FU ; Yi LÜ ; Yong ZHANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2021;42(2):262-266
【Objective】 To investigate the clinical application of self-developed magnetic anchoring device for assisting thoracoscopic pulmonary resection. 【Methods】 Eleven patients underwent thoracoscopic pulmonary assisted with resection magnetic anchoring technique at the Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, from March to May 2019. Their clinical data were retrospectively analyzed. The operation time, blood loss, blood transfusion volume, postoperative hospital stay, and postoperative complications were recorded. 【Results】 There were seven male and four female patients, with the average age of (51.6±13.9) years (range from 22 to 69 years). Three single-port and eight single-utility-port thoracoscopic surgeries were performed. Magnetic instruments provided good surgical field exposure in all operations. Among 11 surgeries, one was converted to thoracotomy and one to three-hole surgery due to enlargement and adhesion of hilar lymph nodes. The operation time was (107.8±63.1) minutes (range of 27-182 minutes). The blood loss was 50 (10-50)mL (range of 5-1 000 mL). No blood transfusion was needed during the operation. The postoperative hospital stay was (5.0±1.8) days (range of 3-9 days). No postoperative complications occurred in all the patients. 【Conclusion】 Magnetic anchor technique can effectively alleviate the "chopstick effect" in thoracoscopic surgery. Magnetic anchor technique is safe and feasible in assisting thoracoscopic pulmonary resection.