No abstract available.
Nipples*

Herein, we report a rare case of Bowen’s disease in the umbilicus. A 42-year-old woman visited our clinic with a brownish-to-blackish plaque on the umbilicus, which was about 0.8 cm in diameter and neither itchy nor painful.Histopathological examination of the lesion revealed Bowen’s disease.

Herein, we report a rare case of Bowen’s disease in the umbilicus. A 42-year-old woman visited our clinic with a brownish-to-blackish plaque on the umbilicus, which was about 0.8 cm in diameter and neither itchy nor painful.Histopathological examination of the lesion revealed Bowen’s disease.

Herein, we report a rare case of Bowen’s disease in the umbilicus. A 42-year-old woman visited our clinic with a brownish-to-blackish plaque on the umbilicus, which was about 0.8 cm in diameter and neither itchy nor painful.Histopathological examination of the lesion revealed Bowen’s disease.

Herein, we report a rare case of Bowen’s disease in the umbilicus. A 42-year-old woman visited our clinic with a brownish-to-blackish plaque on the umbilicus, which was about 0.8 cm in diameter and neither itchy nor painful.Histopathological examination of the lesion revealed Bowen’s disease.

BACKGROUND: Recently, the incidence of hepatitis A virus (HAV) infection has been increasing in Korea, and an outbreak among healthcare workers (HCWs) has also been reported. This study aims to evaluate the seroepidemiology of hepatitis A among HCWs at an 820-bed teaching hospital in Korea, thereby facilitating HAV vaccination for these HCWs. METHODS: In June 2009, we assessed the total immunoglobulins against the HAV in the serum samples of 907 HCWs by using VIDAS Anti-HAV Total (bioMerieux, France). RESULTS: Seropositivity for HAV significantly increased with age (P<0.001): 0% for < or =25 years, 9.4% for 26-30 years, 39.5% for 31-35 years, 66.7% for 36-40 years, 85.7% for 41-45 years, 96.0% for 46-50 years, 98.3% for 51-55 years, 95.8% for 56-60 years, and 100% for > or =61 years. CONCLUSION: Since HCWs aged 20-40 years show low seropositivity for HAV vaccination against hepatitis A should be considered in all these HCWs.
Aged ; Delivery of Health Care ; Hepatitis ; Hepatitis A ; Hepatitis A Antibodies ; Hepatitis A virus ; Hospitals, Teaching ; Humans ; Immunoglobulins ; Incidence ; Korea ; Seroepidemiologic Studies ; Vaccination

No abstract available.
Gingiva* ; Periodontitis ; Protein Isoforms* ; Superoxide Dismutase* ; Superoxides*

BACKGROUND: Recently, the prevalence of colorectal cancer related with metabolic syndrome is increasing in Korea. The aim of this study was to reveal a relationship between components of metabolic syndrome and the development of colon polyp. METHODS: Among the subjects who visited a health promotion center of one university hospital and underwent colonoscopic examination from February 2010 to February 2011, a total of 1,630 (males 1,156, females 474) asymptomatic adults were included for the study. Sex, age, body mass index, waist circumference, blood pressure, fasting blood glucose, total cholesterol, triglyceride, HDL-cholesterol levels and the presence of colorectal polyps were measured. Alcohol consumption, smoking and exercise were assessed by a self-administered questionnaire. Metabolic syndrome was defined by criteria of 2004 American Heart Association/Updated NCEP Adult Treatment Panel III. RESULTS: The prevalence of colon polyps and metabolic syndrome was 21.7% and 16.0% respectively among study subjects. After adjustment for sex and age, metabolic syndrome (odds ratio [OR]=1.72, 95% confidence interval [CI] 1.05-2.82, P=0.031) and waist circumference (OR=1.04, 95% CI 1.01-1.06, P=0.009) were associated with increased risk of colorectal polyps. CONCLUSION: Metabolic syndrome and waist circumference were associated with increased risk of colon polyps in asymptomatic Korean adults.
Adult* ; Alcohol Drinking ; Blood Glucose ; Blood Pressure ; Body Mass Index ; Cholesterol ; Colon* ; Colorectal Neoplasms ; Fasting ; Female ; Health Promotion ; Heart ; Humans ; Korea ; Polyps* ; Prevalence ; Smoke ; Smoking ; Triglycerides ; Waist Circumference ; Surveys and Questionnaires

Influenza virus infection is a common respiratory disease in children. Renal complications of influenza infection were not commonly encountered until the 2009 H1N1 influenza pandemic, when acute kidney injury (AKI) frequently developed in severely ill patients. Kawasaki disease (KD) is another rare association in pandemic influenza virus infections. There are some reports about KD coincident with influenza A H1N1/09 infection. However, simultaneous AKI and KD in influenza A or B virus infections have never been reported. Herein, we report the first case of influenza B virus infection that initially presented as AKI but was subsequently diagnosed as atypical KD.
Acute Kidney Injury* ; Child ; Herpesvirus 1, Cercopithecine ; Humans ; Influenza B virus* ; Influenza, Human ; Mucocutaneous Lymph Node Syndrome* ; Orthomyxoviridae ; Pandemics

PURPOSE: Airways eosinophilia and increased IgE, characteristic features of asthma, result from a predominant Th2 response. In this study, we investigated the effect of CpG oligodeoxynucleotides (ODNs) on the inhibition of airways eosinophilia in mice with established airway inflammation. We also investigated the immunological mechanisms involved. METHODS: Groups of BALB/c mice were sensitized intradermally with ovalbumin(OVA). At week 10, airway inflammation was induced by intranasal challenge of the mice with OVA. At week 14, the mice were challenged intranasally again with OVA in the presence and without the presence of CpG ODNs. Mice with saline administration served as negative controls. Bronchoalveolar lavage fluids(BALF) were obtained and eosinophils were counted. Th1 and Th2 cytokines in the spleen cell cultures were measured by ELISA. Serum OVA-specific IgE and IgG2a antibodies were also measured by ELISA. RESULTS: BALF eosinophils were significantly inhibited in the CpG ODNs-treated mice(P<0.01). IgE and IgG2a levels increased significantly in both CpG ODNs-treated and untreated groups as compared to the negative control group; there was, however, no significant difference between the two groups four days after intranasal administration of CpG ODNs. Cytokine analysis revealed decreased production of IL-4, IL-5, and IL-13 and increased production of IL-12 in the CpG ODNs-treated group as compared to the untreated group. Interestingly, IFN-gamma levels were not upregulated in the CpG ODNs-treated group. CONCLUSION: CpG ODNs vaccination is a potentially useful approach for reversing airways eosinophilia in mice with established airways inflammation.
Administration, Intranasal ; Animals ; Antibodies ; Asthma ; Bronchoalveolar Lavage ; Cell Culture Techniques ; Cytokines ; Enzyme-Linked Immunosorbent Assay ; Eosinophilia ; Eosinophils ; Immunoglobulin E ; Immunoglobulin G ; Inflammation* ; Interleukin-12 ; Interleukin-13 ; Interleukin-4 ; Interleukin-5 ; Mice* ; Oligodeoxyribonucleotides* ; Ovum ; Spleen ; Vaccination