2.ClassⅠ Integron and Its Correlation with Genes Coding for ESBLs in ESBLs-producing Escherichia coli and Klebsiella pneumoniae
Yingmei FU ; Fengmin ZHANG ; Wenli ZHANG ; Heguang ZHANG ; Xiaobei CHEN ; Weiyuan GUO ; Jiayu MA
Chinese Journal of Nosocomiology 2006;0(03):-
OBJECTIVE To survey the distribution of class Ⅰ integron in extended-spectrum beta-lactamases(ESBLs)-producing Escherichia coli and Klebsiella pneumoniae and its contribution in horizontal transfer of ESBLs genes.METHODS The presence of class Ⅰ integron among 230 ESBLs-producers and 197 non-ESBLs-producers of E.coli and K.pneumoniae were detected by PCR.The correlation and co-transfer between integron and genes coding for SHV,CTX and TEM were studied. RESULTS One hundred and thirty-seven(59.6%) isolates were positive for intⅠ gene among ESBLs-producers,contrasted to 48(24.4%) in non-ESBLs-producers(P
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