The purpose of this study was to investigate the distribution of eruption disturbance and to analyze its causes, treatment methods, and duration of orthodontic traction, based on 703 patients with eruption disturbance who were treated in the pediatric dental clinic of Seoul National University Dental Hospital between July 2011 and June 2016.Eruption disturbance in pediatric patients was most prevalent in the maxillary canine, followed by the maxillary central incisor and maxillary first molar. Eruption disorder of the maxillary canine was more common in females (p < 0.001), whereas the maxillary central incisor (p = 0.009), maxillary first molar (p < 0.001) and mandibular first molar (p = 0.028) were more common in males than females.The most common causes of eruption disturbance were abnormality of the eruption pathway and the presence of obstacles in the pathway. Orthodontic traction was the most prevalent treatment choice for eruption disorder, mostly done for the maxillary central incisors. The duration of orthodontic traction was shorter with younger age (p < 0.001) and lower crown position (p < 0.001).It is important for pediatric patients to detect eruption disorders early through regular checkup, and it is necessary to initiate treatment at an appropriate time with an accurate diagnosis and treatment plan.
Crowns ; Dental Clinics ; Diagnosis ; Female ; Humans ; Incisor ; Male ; Methods ; Molar ; Seoul ; Traction

Background: Infants and very young children with malignant brain tumors have a poorer survival and a higher risk for neurologic deficits. The present study evaluated the feasibility and effectiveness of multimodal treatment including tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) in minimizing use of radiotherapy (RT) in very young children with non-metastatic malignant brain tumors. Methods: Twenty consecutive patients younger than 3 years were enrolled between 2004 and 2017. Tandem HDCT/auto-SCT was performed after six cycles of induction chemotherapy.Local RT was administered only to patients with post-operative gross residual tumor at older than 3 years. Since September 2015, early post-operative local RT for patients with atypical teratoid/rhabdoid tumor or primitive neuroectodermal tumor was administered. Results: All 20 enrolled patients underwent the first HDCT/auto-SCT, and 18 proceeded to the second. Two patients died from toxicity during the second HDCT/auto-SCT, and four patients experienced relapse/progression (one localized and three metastatic), three of whom remained alive after salvage treatment including RT. A total of 17 patients remained alive at a median 7.8 (range, 2.5−15.7) years from diagnosis. Nine survivors received no RT, six survivors received local RT alone, and two survivors who experienced metastatic relapse after tandem HDCT/auto-SCT received both local and craniospinal RT. The 5-year overall, eventfree, and craniospinal RT-free survival rates were 85.0% ± 8.0%, 70.0% ± 10.2%, and 75.0% ± 9.7%, respectively. Neuroendocrine and neurocognitive functions evaluated 5 years after tandem HDCT/auto-SCT were acceptable. Conclusion Our results suggest that non-metastatic malignant brain tumors in very young children could be treated with multimodal therapy including tandem HDCT/auto-SCT while minimizing RT, particularly craniospinal RT.

A 43-year-old male presented with daytime sleepiness at work and indifferent behavior like never before. Two weeks prior to hospital admission, he had episodic memory loss with well preserved remote memory. Brain MRI showed a dural arteriovenous fistula (DAVF) in the right lateral transverse sinus with a bilateral thalamic venous infarction. Cerebral angiography confirmed a right transverse sigmoid dural arteriovenous fistula with a feeding artery of the right occipital artery and left posterior meningeal artery. The DAVF was completely eliminated through multiple endovascular interventions. Recently, endovascular treatment has become one of the main therapeutic options to obliterate a fistulous site, which has led to a rapid diagnostic approach and management of DAVFs with high curative rates. We report a rare case of posterior fossa located at a dural arteriovenous fistula that caused rapid progressive dementia and was successfully eliminated through only endovascular treatment.
Adult ; Arteries ; Brain ; Central Nervous System Vascular Malformations* ; Cerebral Angiography ; Colon, Sigmoid ; Dementia* ; Embolization, Therapeutic ; Humans ; Infarction ; Magnetic Resonance Imaging ; Male ; Memory, Episodic ; Memory, Long-Term ; Meningeal Arteries