No abstract available.
Bronchiolitis ; Epidemiology ; Pneumonia ; Respiratory Syncytial Viruses

Prader-Willi syndrome is characterized by infantile hypotonia, mental retardation, hyperhagia, hypogonadism and obesity. Approximately 60% of all PLW syndrome show an interstitial deletion of chromosome 15, 37% have apparently normal chromosome, and 3.6% have a variety of other abnormalities involving chromosome 15. Diabetes mellitus has been considered a component of PLW syndrome and the incidence is about 7%. We experienced a 17-year-old female who revealed mental retardation, hypogonadism, obesity, and non-insulin dependent type DM, compatible with Prader-Willi syndrome.
Adolescent ; Chromosomes, Human, Pair 15 ; Diabetes Mellitus* ; Female ; Humans ; Hypogonadism ; Incidence ; Intellectual Disability ; Muscle Hypotonia ; Obesity ; Prader-Willi Syndrome*

Eight patients in the state of ASA classification l, ll were investigate. Blood samples were collected before, just after, 30 minutes after and 60 minutes after induction of anesthesia. Glucose and electrolyte changes in relation to maintenance fluids in balanced and halothane anesthesia were as follows. 1) In both anesthetic techniques blood sugar level showed increasing tendency according to duration of anesthesia. 2) There were no specific changes in serum electrolytes related to type of anesthesia. 3) The administration of D/S and H/D showed a little increase in Na+ and Cl- level compared to the administration of just DsW. 4) The administration of H/d showed less increase in K+ level than the administration of DsW or D/S. 5) Just after induction of anesthesia the K+ level increased a little and decreased gradually thereafter.
Anesthesia ; Anesthesia, General* ; Blood Glucose* ; Classification ; Electrolytes* ; Glucose ; Halothane ; Humans

The American Academy of Pediatrics and American Academy of Family Physicians developed the clinical practice guideline on the management of acute otitis media. The American Academy of Pediatrics, American Academy of Family Physicians, and American Academy of Otolaryngology-Head and Neck Surgery developed the clinical practice guideline on the diagnosis and management of otitis media with effusion. These two guidelines provide evidence-based recommendations.

PURPOSE: Several studies have proven that EGCG, the primary green tea catechin, and glucosamine-6-phosphate (PGlc) reduce triglyceride contents in 3T3-L1 adipocytes. The objective of this study is to evaluate the combination effect of EGCG and PGlc on decline of accumulated fat in differentiated 3T3-L1 adipocytes. METHODS: EGCG and PGlc were administered for 6 day for differentiation of 3T3-L1 adipocytes. Cell viability was measured using the CCK assay kit. In addition, TG accumulation in culture 3T3-L1 adipocytes was investigated by Oil Red O staining. We examined the expression level of several genes and proteins associated with adipogenesis and lipolysis using real-time RT-PCR and Western blot analysis. A flow cytometer Calibar was used to assess the effect of EGCG and PGluco on cell-cycle progression of differentiating 3T3-L1 cells. RESULTS: Intracelluar lipid accumulation was significantly decreased by combination treatment with EGCG 60 microM and PGlc 200 microg/m compared with control and EGCG treatment alone. In addition, use of combination treatment resulted in directly decreased expression of PPARgamma, C/EBPalpha, and SREBP1. In addition, it inhibited adipocyte differentiation and adipogenesis through downstream regulation of adipogenic target genes such as FAS, ACSL1, and LPL, and the inhibitory action of EGCG and PGlc was found to inhibit the mitotic clonal expansion (MCE) process as evidenced by impaired cell cycle entry into S phase and the S to G2/M phase transition of confluent cells and levels of cell cycle regulating proteins such as cyclin A and CDK2. CONCLUSION: Combination treatment of EGCG and PGlc inhibit-ed adipocyte differentiation through decreased expression of genes related to adipogenesis and adipogenic and cell cycle arrest in early stage of adipocyte differentiation.
3T3-L1 Cells ; Adipocytes* ; Adipogenesis* ; Blotting, Western ; Catechin ; Cell Cycle Checkpoints* ; Cell Cycle* ; Cell Survival ; Cyclin A ; Lipolysis ; Phase Transition ; PPAR gamma ; S Phase ; Tea ; Triglycerides

Respiratory syncytial virus is the most common cause of lower respiratory infection (bronchiolitis and pneumonia) of infancy and early childhood. We analyzed clinical and radiological features of 76 patients with lower respiratory infections by respiratory syncytial virus, which were diagnosed by indirect immunofluorescent test or culture of nasal aspirate in Hep-2 cell monolayer, during the period of January-December, 1991. There were peaks of incidences in March-May and November-December, accounting for 87% of eases. Sixty-two cases (82%) were under 1 year of age. Fifty cases(66%) had underlying diseases. Major radiographical findings were overaeration (83%), parahilar peribronchial infiltrates(67%), segmental or subsegmental atelectasis(32%), and segmental or lobar consolidation(16%). In 15 cases(20%), overaeration was the only radiological findings. There was no evidence of pleural effusion or hilar lymph node enlargement in all cases. By considerig clinical features(symptoms, age. Underlying diseases, epidemic seasons) in addition to the radiological findings, radiologists would be familiar with lower respiratory infection by respiratory syncytial virus. Air space consolidation, which is generally though to represent bacterial pneumonia, is also observed not infrequently in respiratory syncytial virus infections.
Child* ; Humans ; Incidence ; Infant* ; Lymph Nodes ; Pleural Effusion ; Pneumonia, Bacterial ; Respiratory Syncytial Virus Infections ; Respiratory Syncytial Viruses* ; Respiratory Tract Infections

PURPOSE: This study was done to identify the effectiveness of CPR training for nurses in the 6-sigma course. METHOD: The participants were nurses and doctors who worked in the medical center. For data analysis, the SPSS/PC14.0 program was used. RESULT: The total 11 categories of the primary problems were revealed on the recognition of carrying out CPR by nurses and doctors. After understanding the nurses' CPR knowledge and the practical ability, the survey showed 14.97 points and 67.12 points. After the education, the scores were increased from 14.87 to 23.25 in knowledge and from 67.12 to 93.43 in practical ability. The 6-sigma problem was ended as worked up the management plan and understood the changes over the management improving team. CONCLUSION: This study carries an emphasis on understanding of various CPR performance problems applied with 6-sigma in ward. In addition, improvement activities in relation to policy of hospitals suggest the high possibilities that the application of the improvement activities could be extended into the entire hospitals.
Cardiopulmonary Resuscitation ; Lifting ; Statistics as Topic

PURPOSE: This study was done to identify the effectiveness of CPR training for nurses in the 6-sigma course. METHOD: The participants were nurses and doctors who worked in the medical center. For data analysis, the SPSS/PC14.0 program was used. RESULT: The total 11 categories of the primary problems were revealed on the recognition of carrying out CPR by nurses and doctors. After understanding the nurses' CPR knowledge and the practical ability, the survey showed 14.97 points and 67.12 points. After the education, the scores were increased from 14.87 to 23.25 in knowledge and from 67.12 to 93.43 in practical ability. The 6-sigma problem was ended as worked up the management plan and understood the changes over the management improving team. CONCLUSION: This study carries an emphasis on understanding of various CPR performance problems applied with 6-sigma in ward. In addition, improvement activities in relation to policy of hospitals suggest the high possibilities that the application of the improvement activities could be extended into the entire hospitals.
Cardiopulmonary Resuscitation ; Lifting ; Statistics as Topic

PURPOSE: This study was conducted to examine the effects of simulation-based education regarding care in a cardio-pulmonary emergency care as related to knowledge, clinical performance ability, and problem solving process in new nurses. METHODS: An equivalent control group pre-post test experimental design was used. Fifty new nurses were recruited, 26 nurses for the experimental group and 24 nurses for the control group. The simulation-based cardio-pulmonary emergency care education included lecture, skill training, team-based practice, and debriefing, and it was implemented with the experimental group for a week in May, 2009. Data were analyzed using frequency, ratio, chi-square, Fisher's exact probability and t-test with the SPSS program. RESULTS: The experimental group who had the simulation-based education showed significantly higher know-ledge (t=5.76, p<.001) and clinical performance ability (t=5.86, p<.001) for cardio-pulmonary emergency care compared with the control group who had traditional education but problem solving process was not included (t=1.11, p=.138). CONCLUSION: The results indicate that a simulation-based education is an effective teaching method to improve knowledge and clinical performance ability in new nurses learning cardio-pulmonary emergency care. Further study is needed to identify the effect of a simulation-based team discussion on cognitive outcome of clinical nurses such as problem solving skills.
Adult ; Cardiopulmonary Resuscitation/*nursing ; *Clinical Competence ; *Competency-Based Education ; Educational Measurement ; Emergency Medical Services ; Female ; Humans ; Male ; *Problem Solving ; Program Evaluation ; Questionnaires ; Young Adult

PURPOSE: The purpose of this study was to develop an instrument to assess emergency room nurses' knowledge and performance of triage nursing. METHODS: The instrument was developed through the stages of conceptual construction, item development, and validity and reliability testing. For the validity and reliability testing, data collected from 48 emergency room nurses using questionnaires was analyzed through descriptive statistics, factor analysis, and reliability coefficients. RESULTS: The knowledge part consisted of 30 items in nine areas, and its reliability was low (KR-20 =0.50). The correct answer rate was 71.8%. The performance section derived from the factor analysis was composed of two factors with nine items in the triage domain and three factors with 12 items in the non triage domain. The explanatory powers of these factors for the domains were 66.1% and 70.4%, respectively. The overall reliability (Cronbach's alpha) was .95, and the reliabilities for the two domains were .88 and .91, respectively. The nurses' mean performance level was 3.2(+/-0.45). CONCLUSION: The specific contents of the triage nursing work were identified from the developed scale; further research is necessary to in order to develop a scale capable of higher reliability and validity.
Emergencies* ; Emergency Service, Hospital* ; Nursing* ; Reproducibility of Results ; Triage*