BACKGROUND: CO laser emiis energy in the mid portion of the infrared spectrum at a wavelengt,h of 10,600nm. The CO laser is the workhorse laser in the treatment of cuianeous disease. With water as the chromophore(light-absorbing compound), CO laser light is highy absorbed in biologic tissue. Human body tissue comprises between 75% to 90% of water. The CO laser is superficially absorbed by tissue water, with little scatter, limiting penetration into the skin to less than 0.1 mm. The beam can be delivered with a large spot size and low power density(defocus mode) or focused tightly with great power density(focused mode). AS A RESULT: the CO laser may be used both to vaporize and to cut tissue while coagulating blood vessels, providing a relatively bloodless su gical field. OBJECTIVE: The purpose of this study was to evaluate the therapeutie effect of the CO laser on benign cutaneous tumors. MEHTODS: 114 cases of benign cutaneous tumors treated with the CO laser between October 1987 and September 1992 were subjected to detailed analysis, The CO later is Pizer Laser system(U.S.A., Ca) Model 20-C CO. The laser produces power output that ranges from 0 to 25 W of continuous wave. Spot size is variable, between 0.3mm and 2mm. RESULTS: 1. Angiofibromas and seborcheic keratoses showed very good response(95.3%, 92.8% ). 2. Syringomas showed a good esponse(82.8%). 3. Epidermal nevus and trichovpitheliomas showed a fair response(58.5%, 60%). 4. There were hypertrophic scars(10.5%) and transient hypopigmentation. CONCLUSION: The Co laser was a very effective modality for the treatment of benign cutaneous tumors such as angiofibromas, seborrheic keratosis and syringomas.
Angiofibroma ; Blood Vessels ; Carbon Dioxide* ; Carbon* ; Human Body ; Hypopigmentation ; Keratosis ; Keratosis, Seborrheic ; Lasers, Gas* ; Nevus ; Skin ; Syringoma ; Water

Allergic contact dermatitis to topical agents mostly results from vehicles and preservatives and rarely from the active ingredients. Ribavirin, an active ingredient of Viramid® cream, is a synthetic nucleoside derivative with broad spectrum activity against a wide variety of DNA and RNA viruses. We report an 18-year-old woman, who had a perioral edematous patch with exudative crusts after topical application of Viramid® cream (nsung pharmaceutical Co., Korea) for the treatment of herpes labiahs. A patch test showed that the sensitizer was ribavirin, the active ingredient of the antiviral agent, Viramid® cream.
Adolescent ; Dermatitis, Allergic Contact* ; DNA ; Female ; Humans ; Patch Tests ; Ribavirin* ; RNA Viruses

Allergic contact dermatitis to topical agents mostly results from vehicles and preservatives and rarely from the active ingredients. Ribavirin, an active ingredient of Viramid® cream, is a synthetic nucleoside derivative with broad spectrum activity against a wide variety of DNA and RNA viruses. We report an 18-year-old woman, who had a perioral edematous patch with exudative crusts after topical application of Viramid® cream (nsung pharmaceutical Co., Korea) for the treatment of herpes labiahs. A patch test showed that the sensitizer was ribavirin, the active ingredient of the antiviral agent, Viramid® cream.
Adolescent ; Dermatitis, Allergic Contact* ; DNA ; Female ; Humans ; Patch Tests ; Ribavirin* ; RNA Viruses

No abstract available.
Cell Proliferation* ; Cytomegalovirus* ; Humans*

No abstract available.
Facial Paralysis* ; Fascia Lata* ; Fascia*

Neurofibromatosis is a syndrome of multiple neurofibromas, abnormal skin pigmentation and certain bony abnormalities. Sometimes the growth of plexiform neurofibromatosis on the face or trunk is centripetal and usually involves the mediastinum and skull base. However, it is very rare that neurofibromatosis involves the trigeminal ganglion. Its encroachment around the foramina of the skull base may induce facial palsy or conductive hearing loss. The guiding principle in the treatment of generalized neurofibromatosis is a radical excision with preservation of vital structures and an immediate reconstruction of the bony skeleton and soft tissue defect. The authors experienced 4 cases of neurofibromatosis involving the trigeminal ganglion. All had trigeminal symptoms for 3 to 4 years. These were severe headache and intractable trigeminal neuralgia. Tumors in all 4 cases were spread in the centripetal type from extracranial neurofibromatosis. The facial nerve was affected in 4 cases. Malignat Schwannoma occurred in 1 case. Accurate diagnosis and assessments were necessary with CT, MRI art oomputer-aided simulation design. Intraoperative bleeding was minimal with hypotensive anesthesia. Surgical approach to the middle cranial fossa involved temporary removal of the zygomatic arch and TMJ disarticulation with downward traction of the mandible. Satisfactory results have been obtained far 3 to 7 years(mean 5 years) follow-up.
Anesthesia ; Cranial Fossa, Middle ; Diagnosis ; Disarticulation ; Facial Nerve ; Facial Paralysis ; Follow-Up Studies ; Headache ; Hearing Loss, Conductive ; Hemorrhage ; Magnetic Resonance Imaging ; Mandible ; Mediastinum ; Neurilemmoma ; Neurofibromatoses* ; Neurofibromatosis 1 ; Skeleton ; Skin Pigmentation ; Skull Base ; Temporomandibular Joint ; Traction ; Trigeminal Ganglion* ; Trigeminal Neuralgia ; Zygoma

This study was conducted to assess macro- and micronutrient compositions in school lunch menus based on the 'Dietary Guideline' for School Lunches. Ninety-five dieticians in elementary school in Chungbuk were asked to complete a questionnaire on characteristics of the school lunch program (such as type of foodservice, food production system), the information about dietitians (such as age, education, and job history), and the extent of the use of processed foods and frozen foods. They were asked to return the questionnaire with the menus including the name and the quantity of every food ingredient offered during a week. A total of 554 lunch menus provided for a week of June 2004 were analyzed. Average nutrient content per meal was as follows; 660 kcal, energy; 92.9 g, carbohydrate; 26.7 g, protein; 21.1 g, fat; 287 microgramRE, vitamin A; 0.5 mg, thiamin; 0.5 mg, riboflavin; 29.3 mg, vitamin C; 338.2 mg, calcium; 3.9 mg, iron; and 97 mg, cholesterol. Average percentages of energy from carbohydrate, protein and fat was 56.2%, 16.2%, and 29.0%, respectively. The mean nutrient content per meal was higher in rural-type than in urban-type schools. The weekly menu of 40% of the schools provided < 55% of energy from carbohydrate, and 39% of the schools offered lunch that provided > or =30% of energy from fat. The micronutrient content was generally high when the percent energy from fat was less than 25%. Our results showed that only 52.6% of the schools provided lunches with the energy composition as in the 'Dietary Guideline' of School Lunches. Whole Milk was the major contributor to fat, saturated fatty acid and cholesterol. We suggest that school foodservices start to provide low fat milk instead of whole milk to reduce fat, saturated fatty acid and cholesterol. If low fat milk is served instead of whole milk, percentage of energy from fat and saturated fat can be reduced from 29% to 25%, and from 10.2% to 9.1%, respectively, and cholesterol could be reduced from 97 mg to 79 mg. Efforts to meet 'Dietary Guideline' for School Lunches should be made, especially to reduce fat intake, while maintaining essential nutrient intake at sufficient levels for children.
Ascorbic Acid ; Calcium ; Child ; Cholesterol ; Chungcheongbuk-do ; Education ; Frozen Foods ; Humans ; Iron ; Lunch* ; Meals ; Micronutrients ; Milk ; Nutritionists ; Riboflavin ; Vitamin A

To introduce an OEM course of problem-based learning(PBL) on tutorial basis, we developed the case-studies on both clinical and community contexts. The 2nd grade medical students were divided into eight small groups. The case-study course was for 3 weeks from September 30 to October 14 in 1998. There were 3 steps for design of case-study course : course planning, implementation, and evaluation which were conducted by 3 tutors and 91 students. We developed 32 cases, and a student solved 3 clinical cases during 3 weeks. There were 3 cases which were the case I(metals), the case II(solvent) and the case III(systemic toxicity). The case-study program was evaluated with questionnaire survey method at the start and end of the course by students. We obtained satisfactory responses from students. Multiple-choice tests revealed that students in case-study group had significantly(P<0.05) higher score than those attended the standard lecture. We concluded that problem-based learning with specific occupational contents is well accepted by students and improves their occupational medicine knowledge.
Surveys and Questionnaires ; Humans ; Occupational Medicine ; Problem-Based Learning* ; Students, Medical

No abstract available.
Cytomegalovirus* ; Humans* ; Methotrexate* ; Papaverine*

No abstract available.
Capsid Proteins* ; Capsid* ; Genome*