1.Mature Cystic Teratoma of the Fallopian Tube: A case report.
Kye Weon KWON ; Jong Yup BAE ; Hee Jung AHN ; Yoon Jung AHN ; Bok Soo KIM
Korean Journal of Pathology 1996;30(10):951-953
Teratomas of the fallopian tube are extremely rare, and only about 50 cases have reported in the world literature. Most cases of mature cystic tubal teratoma are asymptomatic and are discovered as an incidental finding on physical or radiologic examination, or at the time of laparatomy. We report a case of mature cystic teratoma of the right fallopian tube which was discovered during pelvic ultrasonogram for antenatal care in a 28 year old woman. Right salpingectomy was performed during cesarean section for cephalo-pelvic distortion at IUP 39 weeks. Gross examination of the right fallopian tube reveals a distended fallopian tube, measuring 8cm in length and 2cm in diameter. On section, it is filled with several small pedunculated nodules and cysts containing sebaceous materials. Microscopically the tumor was seen in continuity with the lining epithelium of mucosal folds. The majority of the tumor was composed of well differentiated mature elements of three germ layers with skin and skin appendages, mature brain tissue, bone, breast tissue, intestinal mucosa and bronchial epithelium.
Female
;
Humans
;
Cysts
2.Expression of CD44 in Epithelial Ovarian Tumors.
Kye Weon KWON ; Hee Jeong AHN ; Yoon Jeong CHOI ; Hee Jae JOO ; Nam Hoon CHO
Korean Journal of Pathology 1998;32(8):596-602
CD44 is a hyaluronic acid receptor that exists as a standard 90-kd form (CD44H) as well as several CD44 variants isoforms are produced through alternative splicing. Alternatively spliced variants of the CD44 molecule have been found to be associated with invasive and metastatic potential of cancer cells and poor prognosis in several types of carcinoma. The purpose of the present study is to define the expression of CD44H and CD44v6 in ovarian tumors and to investigate whether the expression of these molecules is associated with adverse prognosis. We evaluated the expression of CD44 isoforms in 58 ovarian tumors by means of immunohistochemistry, and correlated between CD44 expression and the histologic types, tumor grade, peritoneal implants, pseudomyxoma peritonei and FIGO stage. While the CD44H was commonly expressed in ovarian tumors, the CD44v6 was expressed in a minor proportion of serous tumors in comparison with frequent expression of v6 isoform in mucinous tumors. The CD44H expression was significantly higher in stage I/II than in stage III. However, there was no correlation between the expression of CD44 and the presence of peritoneal implants or pseudomyxoma peritonei. These results suggest that CD44H could play an important role in the adhesive function in the lower stage of the ovarian tumor and reduced expression in the higher stage might be related to the metastasis and widespread invasion of ovarian carcinoma cells.
Adhesives
;
Alternative Splicing
;
Female
;
Hyaluronic Acid
;
Immunohistochemistry
;
Mucins
;
Neoplasm Metastasis
;
Ovary
;
Prognosis
;
Protein Isoforms
;
Pseudomyxoma Peritonei
3.Wegener's Granulomatosis Involving Lung and Middle Ear: A case report.
Kye Weon KWON ; Yoon Jung CHOI ; Hee Jeong AHN ; Min Soo HAN ; Dong Hwan SHIN
Korean Journal of Pathology 1998;32(6):470-473
A case of Wegener's granulomatosis is described, with special attention focused on the typical histologic findings and involvement of both middle ear and lung. The patient is a 37-year-old man presented with four-month history of cough and sputum. He had a past history of surgery of both ears because of otitis media followed by left facial palsy. Chest radiographs showed variable sized ill defined nodules in both lower lobes with internal airspace consolidation. Histologic preparations of the open lung biopsy specimens demonstrated a diffusely scattered palisading micro and macrogranulomas with central focus of neutrophils and necrotic collagen surrounded by histiocytes, histiocytic giant cells. Fibrinoid necrosis involved blood vessels and lung parenchyma. Chronic inflammation, diffuse granulation tissue formation and irregular fibrosis are also found in the lung parenchyma. The histologic findings of middle ear which was previously biopsied showed scattered palisading ill defined microgranulomas mixed with fibrotic tissue.
Adult
;
Biopsy
;
Blood Vessels
;
Collagen
;
Cough
;
Ear
;
Ear, Middle*
;
Facial Paralysis
;
Fibrosis
;
Giant Cells
;
Granulation Tissue
;
Granuloma
;
Histiocytes
;
Humans
;
Inflammation
;
Lung*
;
Necrosis
;
Neutrophils
;
Otitis Media
;
Radiography, Thoracic
;
Sputum
;
Vasculitis
;
Wegener Granulomatosis*
4.Leiomyoma of the Urinary Bladder.
Kye Weon KWON ; Hee Jung AHN ; Yoon Jung CHOI ; Young Kwon HONG ; Jae Seop SHIN
Korean Journal of Pathology 1997;31(12):1320-1323
Leiomyoma is commonly found in the female genital tract, but occurrence in the urinary bladder is very rare with only 235 cases reported in the literature. These tumors have been classified as intravesical (63%), intramural (7%) and extravesical (30%) depending on the direction of the growth. We report a case of intravesical leiomyoma of the urinary bladder in a 36 year-old woman who exhibited dysuria and urinary retention. The gross and microscopical findings of leiomyoma of the bladder are similar to those of the uterus. Immunohistochemical stains for estrogen receptor (ER) and progesterone receptor (PR) revealed diffuse nuclear staining in smooth muscle cells, supporting the hypothesis of hormonal influence in tumorigenesis.
Adult
;
Carcinogenesis
;
Coloring Agents
;
Dysuria
;
Estrogens
;
Female
;
Humans
;
Leiomyoma*
;
Myocytes, Smooth Muscle
;
Receptors, Progesterone
;
Urinary Bladder*
;
Urinary Retention
;
Uterus
5.A case of babesiosis in an eight year old Korean boy.
Jae Geon SIM ; Hyun Seung PARK ; Don Hee AHN ; Weon Gyu KHO ; Jong Yil CHAI
Journal of the Korean Pediatric Society 1991;34(10):1417-1421
No abstract available.
Animals
;
Babesiosis*
;
Clindamycin
;
Humans
;
Male*
;
Quinine
6.A case of babesiosis in an eight year old Korean boy.
Jae Geon SIM ; Hyun Seung PARK ; Don Hee AHN ; Weon Gyu KHO ; Jong Yil CHAI
Journal of the Korean Pediatric Society 1991;34(10):1417-1421
No abstract available.
Animals
;
Babesiosis*
;
Clindamycin
;
Humans
;
Male*
;
Quinine
7.Geographical Variations in the Incidence of Childhood Cancer.
Duk Hee LEE ; Hai Rim SHIN ; Kang Weon PARK ; Yoon Ok AHN
Journal of the Korean Cancer Association 1998;30(3):425-434
PURPOSE: The incidence of childhood cancer in the Korea was studied to compare incidence rates between countries and between different regions in Korea. MATERIALS AND METHODS: A tatal of 2,891 cases, registered in the Natinal Cancer Registy from 1993 to 1995, were analysied. Death Certificate Only(DCO) cases were not included. DCO % was estimated about 22%. We calculated the incidence rates according to the International Classification of Childhood Cancer. The age-standardized rates by diagnostic group was compared with those of other countries. The total incidence of childhood cancer were compared among 34 cities in Korea with the rates in the rest of the nation. RESULTS: The crude incidence of all childhood cancer was 94.1 per million. The cumulative incidence to age 15 was 0.137% and the age-standardized rate, calculated using the world standard population, was 96.1 per million. In the incidence rates by diagnostic group, we observed many similarities with other countries in East Asia. The age-standardized rates of E, F and AL cities were significantly higher(p<0.05). In the 0-4 age group, F, AL and BB cities showed higher rates(p<0.05). In 5~9 years and 10~14 years, F city only had higher rates(p<0.05). CONCLUSION: Further study will be needed in order to investigate possible environmental factors which may account for the regional variations.
Classification
;
Death Certificates
;
Far East
;
Humans
;
Incidence*
;
Korea
8.Analysis of Published Papers and their Keywords in the Korean Journal of Women Health Nursing (2003-2006).
Jeung Im KIM ; So Mi PARK ; Hye Sook PARK ; Chae Weon CHUNG ; Suk Hee AHN
Korean Journal of Women Health Nursing 2007;13(1):51-59
PURPOSE: This research was aimed to explore the major subjects and research theme and to classify characteristics of the key words in recent Korean Journal of Women Health Nursing. METHOD: With survey design, whole 103 published papers during 2003-2006 were analyzed with structured analysis form; research subjects, research methodology, data analysis, and key words of the published papers were classified and extracted. Various theme was founded and classified to 9 domains. RESULT: Most of the research subjects were women. Eighty-eight percent of papers conducted quantitative research; 83% chose convenience sampling and 69% used survey design, while experimental design was 29%. Key words were categorized 9 domains: demographic, health related concept, health behavior(intervention), sex-related, life event, disease, et al. Among 9 domains, health related concept, especially psycho-social topics such as depression, anxiety, stress were mostly studied and then physiologic topics such as labor pain, fatigue, and menstrual symptoms. CONCLUSION: Most of the subjects were women and the most common domain studied was health related concepts in Korean Journal of Women Health Nursing. And key words and topics were on women's health issues. We can conclude that Korean Journal of Women Health Nursing has published by her own philosophy.
Anxiety
;
Depression
;
Fatigue
;
Female
;
Humans
;
Labor Pain
;
Nursing*
;
Philosophy
;
Pregnancy
;
Research Design
;
Research Subjects
;
Statistics as Topic
;
Women's Health*
9.A Case Report: Surgical Treatment of Pachydermodactyly .
Se Whan RHEE ; Hee Chang AHN ; Weon Jung HWANG ; Jung Keun OH ; Chang Woo LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2006;33(1):124-126
Pachydermodactyly is a rare distinct form of fibromatosis characterized by acquired, asymptomatic dense fibrosis and fibroblastic proliferation around one or more proximal interphalangeal joints. Intralesional triamcinolone injection may be helpful in improving the clinical appearance. A 20-year-old unemployed female patient gave a four years history of progressive swelling of the fingers affecting predominantly the proximal interphalangeal joints of index fingers of left hand and index, middle fingers of right hand. There was no pain and tenderness. Physical examination, complete blood count, antinuclear antibody, rheumatoid factor were unremarkable and radiograph of both hands showed soft tissue swelling only without bony abnormality. We excised the redundant soft tissue from the both sides of proximal interphalangeal joint with longitudinal elliptical fashion. After operation, the fingers of the patient showed marked improvement cosmetically. There were no motor or sensory changes. Pachydermodactyly was first reported in 1996 in Korea. Histologic features include an increased dermal accumulation of collagen and occasionally an increased number of fibroblast. We report for one patient with pachydermodactyly treated with longitudinal elliptical excision and obtained an improvement of clinical appearance.
Antibodies, Antinuclear
;
Blood Cell Count
;
Collagen
;
Female
;
Fibroblasts
;
Fibroma
;
Fibrosis
;
Fingers
;
Hand
;
Humans
;
Joints
;
Korea
;
Physical Examination
;
Rheumatoid Factor
;
Triamcinolone
;
Young Adult
10.Effects of Ketamine and Clonidine for Caudal Analgesia Produced by Bupivacaine in Pediatric Ambulatory Surgery.
Yu Mee LEE ; Jeong Gill LEEM ; Hee Weon AHN ; Hong Seuk YANG ; Dong Myung LEE ; Sung Lyang CHUNG
Korean Journal of Anesthesiology 1998;34(3):585-591
BACKGROUND: Caudal block has proved to be a satisfactory method of providing perioperative analgesia for pediatric surgery in inguinal and perineal areas. This study was designed to evaluate the effects of ketamine or clonidine as an adjunctive of caudal block produced by bupivacaine. METHODS: One hundred ninety five children aged 1~10 years, undergoing surgery in inguinal and perineal areas as ambulatory cases, were randomly allocated to one of four groups after the induction of general anesthesia; 0.25 % bupivacaine 1 ml/kg(group B), 0.25 % bupivacaine 1 ml/kg with ketamine 0.5 mg/kg(group K), 0.25 % bupivacaine 1 ml/kg with clonidine 1 microgram/kg(group C), and local infiltration group(group L). Postoperative pain was assessed using an objective pain scale and the incidence of side effects, such as urinary retention and nausea/vomiting was observed after surgery. RESULTS: In the group B and L, OPS score was higher and analgesics were more frequently administered than group K and C at the recovery room and at home after discharge(p<0.05). There was no difference between the groups in the incidence of nausea and vomiting but urinary retention at the recovery room was more frequent in group C than other groups(p<0.05). CONCLUSIONS: Caudal block provided more effective postoperative analgesia than local infiltration. In caudal block, the addition of ketamine or clonidine prolongs the duration of postoperative analgesia without significant increase in side effects.
Ambulatory Surgical Procedures*
;
Analgesia*
;
Analgesics
;
Anesthesia, General
;
Bupivacaine*
;
Child
;
Clonidine*
;
Humans
;
Incidence
;
Ketamine*
;
Nausea
;
Pain, Postoperative
;
Recovery Room
;
Urinary Retention
;
Vomiting