No abstract available.
Busan* ; Cytogenetics*

The purpose of this study was to test the effects of position change with 30degree laterally inclined position on pressure sores prevention. This study was designed as a Nonequivalent Control Group Quasi-experiment study. The subjects were collected with convenience sample of 30 patients who were hospitalized at ICU(Intensive Care Unit) of C university hospital in Seoul from March 1 to October 31, 1997. The patients were not able to change of position without help. The 15 patients were assigned to the control group and the other 15 patients to the experimental group. The both group were done position change every 2 hours and were observed whether pressure sores was developed for 2 weeks. For the experimental group, two positioning methods were alternatively used : 30degree right lateral, 30degree left lateral. For the control group, 90degree right and left lateral position were applied instead of 30degree lateral position. New Pressure Risk Assessment Scale was utilized to assess pressure sore risk. It is consists of 8 subscales which reflect sensory perception, skin moisture, activity, mobility, friction and shear, nutritional status, body temperature, and amount of medications(analgesics and sedatives). The results of this study are as follows ; 1. The incidence of pressure sores in total sample was 13 cases(43.3%) : 10 cases(76.9%) in control group, 3 cases(23.1%) in experimental group. the incidence rate of pressure sores in experimental group was significant lower than control group. 2. The sites of pressure scores development were 5 cases in trochanteric region, 4 cases in hip region, 2 cases in flank region, 1 cases in sacral region and 1 case in occipital region. Trochanteric region sores were not developed in experimental group. 3. The mean hospitalized period before pressure sores development were 7.3 day in experimental group and 4.1 day in control group. According to the results from this study, suggestions are as follows ; 1. Development of device which enable to keep 30degree laterally inclined position for 2 hours is needed. 2. It is necessary to study variously and objectively usefulness of 30degree laterally inclined position change which is applied to the other pressure risk assessment scale.
Body Temperature ; Femur ; Friction ; Hip ; Humans ; Incidence ; Intensive Care Units* ; Critical Care* ; Nutritional Status ; Pressure Ulcer* ; Risk Assessment ; Sacrococcygeal Region ; Seoul ; Skin

Purpose of this study is to find out proper means of estimating the urinary mercury excretion the normal individuals. Whole void volume was collected every 2 hours beginning from 6 o'clock in the morning until 6 o'clock next morning. Mercury excretion in each urine specimen was measured by NIOSH recommended dithizone colorimetric method (Method No. : P & CAM 145). Urinary concentration of mercury was adjusted by two means : specific gravity of 1.024 and a gram of creatinine excretion per liter of urine comparing the data with the unadjusted ones. Mercury excretion in 24-hour urine specimen was calculated by adding the amounts measured with the hourly collected specimens of each individual. Statistical analysis of the urinary mercury excretion revealed the following results : 1. Frequency distribution curve of mercury excreted in urine of hourly specimens was best fitted to power function expressed in the form of y=ax(b), Adjustment of the urinary mercury concentration by creatinine excretion was shown to be superior (y=1674x(-1.52)), r(2)=0.95) over nonadjustment(y=2702x(-1.57)), r(2)=0.92) and adjustment by specific gravity of 1.024(y=4535x(-1.66), r(2)=0.93). 2. Both log-transformed mercury excretion in hourly voided specimens and mercury excretion itself in 24 hour specimens showed the normal distributions. 3. The frequency distribution of mercury adjusting the urinary concentration of mercury by creatinine excretion was best fitted to a theoretical normal distribution with the sample means and excretion was best fitted to a theoretical normal distribution with the sample means and standard deviation than those unadjusted or adjusted with specific gravity of 1,024. 4. Average urinary mercury excretions in 24-hour urine specimen in an individual were as follows : a) Unadjusted urinary mercury excretions. mean and standard deviation :18.6+/-13.68 microgramHg/liter. median : 16.0 microgramHg/liter. range : 0.0-55.10 microgramHg/liter. b) Adjusted with specific gravity. mean : 20.7+/-11.76 microgramHg/liter x 0.024/(S.G.-1.000). median : 20.7 microgramHg/liter x 0.024/(S.G.-1.000). range : 0.0-52.9 microgramHg/liter x 0.024/(S.G.-1.000). c) Adjuested with creatinine excretion. mean and standard deviation : 10.5+/-6.98 microgramHg/g creatinine/liter. median : 9.4 microgramHg/g creatinine/liter. range : 0.0-26.7 microgramHg/g creatinine/liter. 5. No statistically significant differences were found between means calculated from 24-hour urine specimens and those from hourly specimens transformed into logarithmic values. (P<0.05).
Creatinine ; Dithizone ; Gravitation ; National Institute for Occupational Safety and Health (U.S.) ; Specific Gravity

The purpose of this study is to identify the effects of a nursing intervention using sensory stimulation in dysphagic patients. Quasi-experimental with a nonequivalent control group pretest-posttest desigr, was used. 15 patients of each group were assigned for this study, who were hospitalized in the oriental medicine hospital of K. University. Specific stimulation plans were devised based on a dysfunctional area of the subjects. For each modality. subjects were systematically stimulated for 30 minutes. in the experimental group prim to each meal and 3 times per day for a week. The data were analyzed by SPSS PC program using chi2test. Wilcoxon Signed Rank test and Mann-Whitney U test. The results of this study are as follows: 1. The tongue contra! score of the experimental group is greater than that of the control group(u=52.0. p= .007). 2. The score of chewing ability. lip control swallowing ability of the experimental group is greater than that of the control group But no difference is statistically seen between the experimental group and control group. Therefore, this study shows that sensory stimulation using icing. quick stretch. etc., was effective in improving oropharyngeal function in patients with dysphagia.
Deglutition ; Deglutition Disorders ; Eating* ; Humans ; Lip ; Mastication ; Meals ; Medicine, East Asian Traditional ; Nursing ; Stroke* ; Tongue

Hamartoma of the bladder is quite a rare entity which is composed of a disorderly admixture of mature cellular elements normally present in the urinary bladder. There is a great controversy regarding the pathogenesis of this lesion. Whether it is a true hamartomatous lesion or metaplastic lesion developed secondary to the inflammatory process. Similar or identical lesions has often been given by other names such as florid examples of cystitis glandularis. We prefer to cell florid examples of cystitis glandularis rather than hamartoma when it was occurred in an old age higher then 50th decade. Here we report a case of hamartoma of the urinary bladder in 44 years old man. Cystoscopic examination revealed a papillary polypoid mass which was attached to the fundus of bladder by long stalk. The mass measured 1.5 cm in greatest diameter. It was composed of epithelial nests resembling von Brunn's nest, cystitis glandularis or cystitis cystica dispersed in a stroma rich in smooth muscle and fibrous tissue.
Hamartoma

Proliferating cell nuclear antigen (PCNA, PC10), an auxillary protein of DNA polymerase, plays a main role in the early stage of DNA Synthesis and is synthesized from Gl phase to s phase of the cell cycle. Nucleolar organizer region (NORs) are DNA loops encoding RNA proteins(AgNORs). To evaluate correlation with PCNA labelling index (LI)and AgNORs according to histological grades and clinical stages of transitional cell carcinoma of the urinary bladder, the authors analysed 54 transitional cell carcinoma using immunohistochemical stain for PCNA and silver stain for AgNORs in paraffin sections. The comparison of PCNA (PC10) LI and clinical stage showed a significant correlation (p<0.05), where as PCNA (PC10) LI according to histologic grade showed no significant correlation. High grade tumors showed increase PCNA LI. Superficial tumors (Ta-Tl) showed significantly lower PCNA LI than muscle invasive tumors (T2-T4)(p<0.05). There was no significant correlation between AgNORs and clinical stage, bur higher stage and higher grade tumors showed increased noubers of AgNORs. These results suggest that PCNA LI has a significant correlation with clinical stages of transitional cell carcinoma of the urinary bladder.

We performed immunohistochemical stain of p-glycoprotein using JSB-1 monoclonal antibody to study multidrug resistant(MDR) gene expression in 137 gastric tumor tissues obtained from 87gastric carcinoma patients. The incidence of p-glycoprotein expression was 60 of 87 cases(69%) and it was not correlated with age, sex, depth of tumor invasion, and lymph node metastasis, but was correlated with histologic type of gastric adenocarcinoma. The distribution of p-glycoprotein positive cells in the tumor tissue was diffuse in 34 cases(73.9%) and focal in 12 cases(26.1%), and the dominant staining patterns of p-glycoprotein in the tumor cells were cytoplasmic and golgi staining in 20 cases(43.5%) and 19 cases(41.3%), respectively, and 7 cases(15.2%) showed fine granules in the cytoplasm. The incidence of p-glyco-protein expression in the tumor tissue was higher in A and AB blood type patients who have A antigen than in 0 and B blood type patients. Cytoplasmic staining pattern was dominant in O and B blood types and golgi staining in A and AB blood type patients. Among 27 patients 'who received chemotherapy, partial remission was noted in 9 of 11 p-glyco-protein negative patients(81.8%) and no remission or progression of the tumor was seen in 9 of 16 p-glycoprotein positive patient(56.3%). The p-glycoprotein expression in gastric carcinoma had no direct correlation with known several prognostic factors of the gastric tumor except for histologic type, and it is supposed that p-glycoprotein detection in gastric tumor tissue by immunohisto-chemical stain is a good method for predicting the response of chemotherapy, especially in p-gly-coprotein negative cases.
Incidence

Congenital esophageal stenosis due to tracheobronchial remnants is one of main forms of congenital esophageal stenosis, and it was first described by Frey and Duschel in l936. An 18-month-old male presented with underdevelopment and dehydration state due to persistent vomiting several times per day since 3 months after his birth. Esophagogram revealed an elongated and diiated esophagus with marked stenosis at distal portion. Partial distal esophagectomy was performed. Histologically, the thickened esophageal wall is composed of tracheobronchial remnants including hyaline cartilages, mucous glands, and ductal structures lined by ciliated respiratory epithelium under stratified squamous mucosa.
Male ; Humans

Congenital esophageal stenosis due to tracheobronchial remnants is one of main forms of congenital esophageal stenosis, and it was first described by Frey and Duschel in l936. An 18-month-old male presented with underdevelopment and dehydration state due to persistent vomiting several times per day since 3 months after his birth. Esophagogram revealed an elongated and diiated esophagus with marked stenosis at distal portion. Partial distal esophagectomy was performed. Histologically, the thickened esophageal wall is composed of tracheobronchial remnants including hyaline cartilages, mucous glands, and ductal structures lined by ciliated respiratory epithelium under stratified squamous mucosa.
Male ; Humans

No abstract available.
Animals ; Ethanol* ; Interleukin-2* ; Interleukin-6* ; Rats*