Subcutaneous fat necrosis is manifested by erythematous tender nodules on the legs, buttock or trunk and is associated with pancreatic disease including acute and chronic pancreatitis, pancreatic carcinoma, pseudocyst, pancreatic stone and other diseases. Its histologic findings are pathognomonic and reveal foci of subcutaneous fat necrosis with "ghost-like" anucleated cells with thick "shadowy wall" and surrounding inflammatory infiltrate consisting of polymorphonuclear cells, eosinophils, lymphocytes, histiocytes, foam cells and foreign body giant cells. We experienced a case of subcutaneous fat necrosis associated with pancreatic adenocarcinoma manifested by subcutaneous nodules in the buttock and lower extremities and by arthralgia of the left knee in a 67-year-old woman. Therefore, we are reporting to emphasize the importance of the skin findings of the internal disease.
Female ; Humans ; Adenocarcinoma

The patient was a 24-year-old Korean man with an extensive nevus flammeus over the rigbt buttock, penis, leg, ankle and dorsal aspect of foot. Varicose veins on the flexor aspect of mid-portion of lower extremity of right side are noted remarkable hypertrophy of the soft tissue and bones are also found on the area where hemangioma is associated with them. Radiological examination of spine, pelvic, femur, tibia and fibula bones showed longer and thicker in affected side (right) than unaffected (left), and vertebral bones showed compensatory scoliosis-convexity to the left (normal side)and damage of vertebral bodies at the level of L-3, 4, 5. These are well established and described as Klippel-Trenaunay-Parkes Weber Syndrome by Klippel, Trenaunay and Parkes-Weber. Authors are made extensive review of literatures of the syndrome and discussions on the type, varient, heredity, sex, onset of age, affected location, racial distribution, right name of syndrorne and differential diagnosis of the syndrome.
Ankle ; Brain Stem Infarctions* ; Buttocks ; Diagnosis, Differential ; Femur ; Fibula ; Foot ; Hemangioma ; Heredity ; Humans ; Hypertrophy ; Leg ; Lower Extremity ; Male ; Penis ; Port-Wine Stain ; Spine ; Tibia ; Varicose Veins ; Young Adult

No abstract available.
Child* ; Diphtheria-Tetanus-Pertussis Vaccine* ; Humans ; Infant*

No abstract available.
Animals ; Chitosan* ; Eating* ; Mice*

No abstract available.
Animals ; Chitosan* ; Rats* ; Water*

No abstract available.
Animals ; Macrophages, Peritoneal* ; Mice*

No abstract available.
Chitosan*

No abstract available.
Leukemia*

The susceptibilities of 45 clinical isolates of bacteroidis fragilis to cefaclor, ciproflxacin and imipenem were determined by new method, E-test (AB Bidisk, Solna, Sweden) and were compared with those from conventional agar dilution method by using brain heart infusion, Mueller-Hinton and Wilk:..s Chalgren agar plates. And the susceptibility of 60 clinical isolates of bacteroides fragilis group (B. fragilis 45 strains, B. distasonis 6 strains, B. ovatus 5 strains, B. thetaiotaomicron 4 strains) to 5 quinolones (ciprofloxacin, enoxacin, norfloxacin, ofloxacin, pefloxacin) were determined by in vitro agar dilution method. Compared with agar dilution MICs for B. fragilis 45 strains, 90.3% of E-test MICs were within +/- 1 dilution of the agar dilutions, and 98.4% were within 2 dilutions. And there were little effect of different medium bases to determine MICs except Mueller-Hinton agar. On Mueller-Hinton agar, B. fragilis showed have or no growth activity. In vitro susceptibility of B. fragilis group to quinolones, most of the test strains showed resistant patterns to quinolones except ofloxacin and there was little difference of susceptibility patterns between species of B. fragilis group.
Agar* ; Bacteroides fragilis* ; Bacteroides* ; Brain ; Cefaclor ; Enoxacin ; Heart ; Imipenem ; Norfloxacin ; Ofloxacin ; Quinolones

To investigate the diagnostic accuracy of ERCP in pancreatobiliary disease, the authors analysed the 1,244 cases of ERCP. The success rate of ERCP was 91.5%. The diagnostic accuracy of ERCP was 93.6% and complications occurred in 2.1%. Complications included pancreatitis,cholangitis and drug reactions. Among the biliary tract disease diagnosed, by ERCP, biliary tract stone was the most common finding. Compared with operative diagnosis of biliary tract stones,the sensitivity of ERCP diagnosis was 92.7% while that of sonographic diagnosis was 81.4%. The specificity of ERCP diagnosis was 94.4% while that of sonagraphic diagnosis was 80.9%. ln the diagnosis of common bile duct stones, ERCP was more accurrate than sonographic diagnosis. The results show that ERCP was a safe and effective diagnostic tool in the assessment of pancreatobiliary tract disease.
Biliary Tract ; Biliary Tract Diseases ; Cholangiopancreatography, Endoscopic Retrograde* ; Common Bile Duct ; Diagnosis ; Sensitivity and Specificity ; Ultrasonography