A 11-year-old, female Russian Blue cat was presented with anorexia, vomiting, and diarrhea lasting for 3 days. Abdominal ultrasonography revealed a hypoechoic, non-circumferential, and eccentrically formed intestinal loop with altered wall layering and thickening of the tunica muscularis. After surgical resection, histopathologic examination confirmed an infiltrative, round-cell neoplasm composed of sheets and cords of neoplastic mast cells within a fibrotic, edematous stroma. The cat was alive and healthy 6 months after surgery. To the best of our knowledge, this is the first reported case of an intestinal mast cell tumor in a Russian Blue cat in South Korea.
Animals ; Anorexia ; Cats* ; Child ; Diarrhea ; Female ; Humans ; Korea ; Mast Cells* ; Ultrasonography ; Vomiting

No abstract available.
Myocardial Bridging* ; Sleep Apnea, Obstructive* ; Spine*

No abstract available.
Myocardial Bridging* ; Sleep Apnea, Obstructive* ; Spine*

Pilot's complacency and confidence have been implicated as a contributing factors in numerous aviation accidents and incidents. It is related to ones belief that one is capable of performing in a certain manner to attain certain goals which is called 'Self-Efficacy' as a psychological concept. The purpose of this study was to construct and validate pilot's self-efficacy scale. This study examined the necessity of pilot efficacy in terms of pilot's confidence and complacency, and considered what is components and processes of pilot self-efficacy through the reference to literature. This Study newly defined 'pilot-efficacy' as vocational self-efficacy in flight operation field. Based on literature review and advisory group's review, there made 3 factors of Pilot-Efficacy:Flight-Efficacy, Relational/Communication Efficacy, and physical and psychological Stress-Coping Efficacy. Preliminary pilot-efficacy scale was administered to pilot group analysis Item analysis was conducted to select appropriate items and common factor analysis was done to identify the subcomponents of pilot efficacy scale. In result, 35 items were selected. The measurement of pilot efficacy for individual makes it possible to predict pilots' behavior when they make decision both normal and non-normal situation. This scale is expected to be not only predictable but also useful to enhance aviation safety. Finally, suggestion for following studies were discussed.
Accidents, Aviation ; Aviation

No abstract available.
Animals ; Dermatitis, Contact* ; Mice*

No abstract available.
Animals ; Calcium* ; Histamine Release* ; Histamine* ; Mast Cells* ; Rats*

PURPOSE: MAGE (melanoma antigen gene) is a tumor associated antigen, presented by HLA class I molecules, which is recognized by cytotoxic T lymphocytes. The expression of MAGE proteins are confined to malignant tumor tissues, except for the normal testis and placental tissues. Therefore, MAGE may be a potential target for immunotherapy of malignant tumors. However, biological aspects associated with the cell cycle are not yet described. MATERIALS AND METHODS: The material used for this study was a novel human squamous cell carcinoma cell line (PNUH-12) from the hypopharynx, which had one point mutation of 78th base, C to G, in exon 7 of p53 gene. To understand the role of MAGE in relation to cell cycle and its relationship with p53 as the Gl checkpoint regulator, the expressions of MAGE-3 protein and mvtant p53 (Mtp53) were accessed by flow cytometry and immunohistochemistry. Double stains for MAGE-3/Mtp53 was analyzed with bivariate flow cytometry. DNA histograms using MAGE-3/PI (DNA) and Mtp53/PI (DNA) were also analyzed. RESULTS: The expression rate of MAGE-3 and Mtp53 were 83% and 85%, respectively. MAGE-3 was expressed in cytoplasm, while M:p53 were expressed in the nuclei of the tumor cells on the immunohistochemical sections. With bivariate analyses, coexpression rate of MAGE-3/Mtp53 was 0.96, and MAGE-3 and Mtp53 constantly showed high levels throughout the cell cycle except Go. CONCLUSIONS: These results mean that (I) MAGE-3 might have yet unknown relationship with mutant p53, (2) expressions of MAGE-3 and Mtp53 are not dependent on the cell cycle in PNUH-12 hypopharyngeal squamous carcinoma cell line, and suggest that MAGE-3 might have a role as important as p53 during the development of malignant tumors.
Carcinoma, Squamous Cell ; Cell Cycle* ; Cell Line ; Coloring Agents ; Cytoplasm ; DNA ; Exons ; Flow Cytometry* ; Genes, p53 ; Humans ; Hypopharynx ; Immunohistochemistry ; Immunotherapy ; Point Mutation ; T-Lymphocytes, Cytotoxic ; Testis

No abstract available.
Dialysis* ; Peritonitis* ; Salmonella*

No abstract available.
Dialysis* ; Peritonitis* ; Salmonella*

PURPOSE: The purpose of this study was to examine the experiences of the use of external breast prostheses among breast cancer survivors in Korea. METHODS: A qualitative descriptive study was conducted, using focus groups. Data were collected from breast cancer survivors who were patients of C women's hospital in Seoul, Korea. Data were analyzed using content analysis in order to identify significant themes. RESULTS: Participants included forty breast cancer survivors who had mastectomy as a surgical treatment. Four themes emerged from the collected data were: 1) concern over the high price of external breast prosthesis, 2) irregular use of external breast prosthesis, 3) unsatisfied with mastectomy bra, and 4) wanting to hide or not to talk about using breast prosthesis openly. CONCLUSION: Since most participants reported irregular use and negative experiences related to external breast prosthesis or mastectomy bra use, healthcare workers should allow more time for proper fitting and counseling and consulting with breast cancer survivors. In addition, health care providers as well as family and friends should keep in mind that cancer survivors need support that can help them cope by using positive reframing. Furthermore, improvements in the coverage of costs and services are needed for these women. This would be helpful for breast prosthesis users.
Breast ; Breast Neoplasms ; Counseling ; Delivery of Health Care ; Female ; Focus Groups ; Friends ; Health Personnel ; Humans ; Korea ; Mastectomy ; Phosphatidylethanolamines ; Prostheses and Implants ; Survivors