No abstract available.

No abstract available.
Family Practice* ; Humans ; Smoke* ; Smoking*

Tegafur is a fluoropyrimidine structurally similar to 5-fluorouracil, used in the treatment of advanced gastrointestinal neoplasms. Mucocutaneous side reactions induced by this agent are rare and include photosensitivity of lichenoid and eczematous types, acral erythema, hyperpigmentation and palmoplantar keratoderma. However, to our knowledge, there has been no report of concurrent development of eruptions of two types in a patient. We describe a female patient with breast cancer, presented with combined features of acral erythema and hyperpigmentation due to oral tegafur.
Breast Neoplasms ; Erythema* ; Female ; Fluorouracil ; Gastrointestinal Neoplasms ; Humans ; Hyperpigmentation* ; Keratoderma, Palmoplantar ; Tegafur*

Acrokeratoelastoidosis of Costa is a rare palmoplantar keratoderma with autosomal dominant inheritance. It is clinically charaeterized by small, firm, yellowish, shiny, translucent papules occumng over the dorsal hands, the knuckles, and the lateral margine of the palms and soles. Histologically, the characteristic features are hyperkeratosis, aeanthosis, and most strikingly, fragmentation of coarse elastic fibers within the dermis. The lesions usually begin in early childhood and progress slowly. We herein report two familial cases of acrokeratoelastoidosis of Costa showing typical clinic1 and histopathological features.
Dermis ; Elastic Tissue ; Hand ; Keratoderma, Palmoplantar ; Wills*

No abstract available.
Epidermal Cyst ; Molluscum Contagiosum ; Molluscum contagiosum virus

A 11-year-old, female Russian Blue cat was presented with anorexia, vomiting, and diarrhea lasting for 3 days. Abdominal ultrasonography revealed a hypoechoic, non-circumferential, and eccentrically formed intestinal loop with altered wall layering and thickening of the tunica muscularis. After surgical resection, histopathologic examination confirmed an infiltrative, round-cell neoplasm composed of sheets and cords of neoplastic mast cells within a fibrotic, edematous stroma. The cat was alive and healthy 6 months after surgery. To the best of our knowledge, this is the first reported case of an intestinal mast cell tumor in a Russian Blue cat in South Korea.
Animals ; Anorexia ; Cats* ; Child ; Diarrhea ; Female ; Humans ; Korea ; Mast Cells* ; Ultrasonography ; Vomiting

Traumatic fat necrosis is a localized reaction of panniculus resulting from blunt trauma occurring predominantly on large pendulous breasts in elderly females and on the face in children. The facial lesions in children need no treatment and therapeutic excision is not indicated because a reasonable cosmetic result comes from spontaneous healing in a year or more. The clinicians unfamiliar with this problem may have confusion in diagnosis and management. Herein we report a case of a three-year-old girl who presented with a 3 cm sized erythematous and bullous plaque on her right cheek. The diagnosis of traumatic fat necrosis was made following clinical and pathological findings.
Aged ; Breast ; Cheek ; Child* ; Diagnosis ; Fat Necrosis* ; Female ; Humans

Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal blistering disease characterized on direct immunofluorescence of perilesional skin by the linear deposition of IgA at the basement membrane zone. The pathogenesis of LABD is not known, but rar ely some cases of LABD have been reported in association with drug exposure. We report a case of drug-induced LABD showing linear deposits of IgA and IgG at the basement membrane zone on direct immunofluorescence of perilesional skin as well as typical clinical and histologic characteristics, although the causative agent could not be specified.
Basement Membrane ; Blister ; Fluorescent Antibody Technique, Direct ; Immunoglobulin A ; Immunoglobulin G ; Linear IgA Bullous Dermatosis* ; Skin

PURPOSE: To compare the efficacy, predictability, safety, and stability of Laser epithelial keratomileusis (LASEK) with conventional Laser in situ keratomileusis (LASIK) for correction of low to moderate myopia. METHODS: In this study, LASIK-treated 31 eyes of 17 patients and LASEK-treated 33 eyes of 17 patients were followed for 6 months. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), manifest refraction, IOP, topography, keratometry, pachymetry and specular examination were performed. RESULTS: Postoperative mean UCVA was logMAR 0.02+/-0.09 in LASIK group and logMAR 0.01+/-0.09 in LASEK group. Postoperative mean refraction was 0.04+/-0.36D in LASIK group and 0.07+/-0.28D in LASEK group and there was no significant difference between 2 groups (P>0.05). 71.0%(22 of 31) of LASIK eyes and 81.8%(27 of 33) of LASEK eyes had an uncorrected visual acuity of 20/20 or better at 6 months after surgery. 87.1%(27 of 31) of LASIK eyes and 97.0%(32 of 33) of LASEK eyes achieved predictability within +/-0.5D at 6 months follow up. There was no decrease in best-corrected visual acuity of two Snellen lines or more in both groups. CONCLUSIONS: In this study, there was no difference in postoperative mean UCVA and mean refraction in LASIK and LASEK group. However, LASEK group had better results in UCVA of more than 20/20 and predictability but there was no significant difference between 2 groups.
Follow-Up Studies ; Humans ; Keratectomy, Subepithelial, Laser-Assisted ; Keratomileusis, Laser In Situ* ; Myopia* ; Visual Acuity

No abstract available.
Urinary Tract Infections* ; Urinary Tract*