PURPOSE: To evaluate the treatment results and prognostic factors after radiotherapy in stage IIB uterine cervix cancer. MATERIALS AND METHODS: We retrospectively analyzed the records of 90 patients with stage IIB uterine cervix cancer who received radiotherapy between 9/94 and 12/99. Age was ranged from 28 to 79 years (median 57). Tumor size was > or = 4 cm in 64 patients. Preteatment SCC level was measured in 76 patients. Twenty nine patients received conventional radiotherapy (QD) and the others received modified hyperfractionated radiotherapy (BID). Only 7 patients in BID had tumor size <4 cm. All patients received high dose rate brachytherapy (4 Gy x 7 or 5 Gy x 6). No patient received concurrent chemotherapy during radiotherapy. Follow up period was ranging from 9 to 76 months (median 38). RESULTS: The 5-year overall and disease free survival rates were 73.4% and 71.6%, respectively. Local recurrences occurred in 10% of patients, and distant metastasis in 18.9%. There was a significant correlation between OS/DFS and tumor size (<4 cm; OS 95.2%, DFS 91.4%, > or = 4 cm; OS 63.4%, DFS 63.4%). Pretreatment SCC level was one of prognostic factors only in univariate analysis. CONCLUSION: With modified hyperfractionated radiotherapy, there was very low local recurrence rate (6.6%) and high 5-year overall and disease free survival rate (75.4% and 70.5%), which is comparable to results after concurrent chemoradiotherapy in bulky, locally advanced stage IIB uterine cervix cancer.
Brachytherapy ; Cervix Uteri* ; Chemoradiotherapy ; Disease-Free Survival ; Drug Therapy ; Female ; Follow-Up Studies ; Humans ; Neoplasm Metastasis ; Radiotherapy* ; Recurrence ; Retrospective Studies

PURPOSE: Kawasaki disease(KD) is known as one of the most important causes of acquired heart disease in children. But the incidence of acquired heart disease can be reduced by early diagnosis and treatment with large amounts of intravenous gamma-globulin(IVGG). For early diagnosis and treatment of atypical KD, we analyzed and compared the clinical features, laboratory findings and coronary lesions in patients with typical or atypical KD. METHODS: A retrospective chart review was conducted in all children with Kawasaki disease who were admitted to the Department of Pediatrics of Kwang-Hye Hospital between January 1998 and December 1999. Except for 15 cases who were not followed, 62 cases were involved in this study. We analyzed and compared the clinical features, laboratory findings and coronary lesions in patients with 39 typical cases and 23 atypical cases of KD. RESULTS: The lowest incidence among clinical symptoms was cervical lymphadenopathy in both groups. In atypical cases, cervical lymphadenopathy, polymorphous exanthema, and changes of peripheral extremities were significantly lower than in typical cases. The duration of fever was similar in both groups, the mean defeverescence time after administration of IVGG in atypical cases was significantly shorter than typical cases(atypical, 2.6 days, typical cases, 1.8 days). The coronary artery dilatation appeared in 4 cases(17.4%) of atypical and 17 cases(43.6%) of the typical group. In most cases of both groups, left coronary artery dilatation was detected. CONCLUSION: To decrease the incidence of serious coronary complications due to atypical KD, careful evauation of clinical findings, early study of echocardiography and early infusion of large doses of IVGG are needed.
Child ; Coronary Vessels ; Dilatation ; Early Diagnosis ; Echocardiography ; Exanthema ; Extremities ; Fever ; Heart Diseases ; Humans ; Incidence ; Lymphatic Diseases ; Mucocutaneous Lymph Node Syndrome* ; Pediatrics ; Retrospective Studies

No abstract available.
Acanthoma*

No abstract available.
Purpura, Thrombocytopenic, Idiopathic*

No abstract available.
Emergencies* ; Emergency Service, Hospital* ; Hospitals, General* ; Humans

PURPOSE: The purpose of this study was to identify the relationship among hesitation factor of questions, critical thinking disposition, and problem solving. METHODS: Data were collected from 370 students at a university in D city using a structured questionnaire from April 1 to April 15, 2015. It was analyzed with frequency analysis, descriptive statistics, t-tests, ANOVA, and correlation analysis. RESULTS: Subjects scored an average of 2.62+/-.52 for hesitation factor of questions, 3.53+/-0.42 for critical thinking disposition, and 3.44+/-0.44 for problem solving. There were significant differences in the three variables according to satisfaction with major, self-expression, and interpersonal relationships. In addition, hesitation factor of questions exhibited a significant difference between genders. Hesitation factor of questions had a negative relationship with critical thinking disposition (r=-.23, p<.001) and with problem solving (r=-.34, p<.001). In addition, there was a statistically significant positive correlation between critical thinking disposition and problem solving (r=.69, p<.001). CONCLUSION: In order to improve critical thinking disposition and problem solving, we need to generate a lot of questions to the student's inside. We also need to develop appropriate teaching methods so that this can be expressed by the actual question coming from the control hesitation factor of questions.
Humans ; Learning ; Problem Solving* ; Teaching ; Thinking*

PURPOSE: The aim of this study was to know whether there is significant difference of peri-implant bone density according to the state of antagonist region. MATERIALS AND METHODS: 51 patients who had implant operation in Daejeon Dental Hospital of Wonkwang University participated in this study and total of 51 implants were analyzed. Implants were classified depending on opposing antagonist region, gender, age and location of jaw. The opposing antagonist region was divided into four groups; natural tooth, implant, pontic and edentulous region. Fractal analysis was performed using two periapical radiographs; one after implant placement and the other after 10 weeks following prosthetic restoration. The analysis was done by Image J. The data was statistically analyzed using one-way ANOVA and Tukey multiple comparison test. RESULTS: The mean value of fractal difference was 0.009 +/- 0.048 with opposing natural tooth, 0.026 +/- 0.080 with opposing implant, 0.025 +/- 0.068 with opposing pontic and 0.093 +/- 0.171 with opposing edentulous area. There was a statistically significant difference in fractal value between opposing implant and opposing edentulous state. And there was no statistically significant difference according to age, gender and location of jaw. CONCLUSION: There was no statistically significant difference between 3 groups except opposing edentulous region and there was a statistically significant difference between opposing implant and edentulous region. And there was no statistically significant difference according to age, gender and location of jaw.
Bone Density* ; Denture, Partial, Fixed ; Fractals* ; Humans ; Jaw ; Tooth

Congenital adrenal hyperplasia is inherited disorder of adrenal steroidogenesis. 21-hydroxylase deficiency is the most commone enzymatic defect and is divided into classic and late-onset or nonclassic forms. Both classic non-classic 21-hydrozylase deficiencies are inherited in a recessive manner as allelic variants. But it is rare that happened in twin infants. Chief complaints of affected twins in our case were ambiguous genitalia, hyperpigmentation and dehydrations. They were revealed into hyponatremia, hyperkalemia and increased amount of serum progesterone, 17-hydroxyprogesterone and urinary 17-ketosteroid excretion and were administered with DOCA, 9alpha-fluorohydrocortisone, hydrocortisone to control the electrolyte imbalance. And now, both of them are going to normal ratio of weight gain and body growth.
17-alpha-Hydroxyprogesterone ; Adrenal Hyperplasia, Congenital* ; Desoxycorticosterone Acetate ; Disorders of Sex Development ; Humans ; Hydrocortisone ; Hyperkalemia ; Hyperpigmentation ; Hyponatremia ; Infant ; Progesterone ; Steroid 21-Hydroxylase* ; Twins* ; Weight Gain

No abstract available.
Hepatitis B Surface Antigens* ; Hospitals, General*

No abstract available.
Lip*