We observed 17 cases of cafe au lait spots histopathplogi ally. Out of 17 cases, 9 cases were neurofibromatosis with neurofibromas, 6 cases were neurofibromatosis without neurofibroma, and 2 cases were normal healthy persons. The results were as follows. l. In all 17 cases, melanin pigment was increased in melanocytes and keratinocytes. 2. Griant pigment granules were identified only in 3 cases of neurofibromatosis with neurofibromas.
Cafe-au-Lait Spots* ; Humans ; Keratinocytes ; Melanins ; Melanocytes ; Neurofibroma ; Neurofibromatoses

We observed clinical and histopathological findings of porokeratosis in 16 cases which comprised 2 linear types, 4 superficial disseminat:ed forms, 4 disseminated superficial actinic porokeratosis and 6 plaque types. From the observation, the following results were obtained. l. Clinical results 1) Eleven cases were men, 5 cases were women, and the sex ratio was 2. 2 to 1, age distribution was from 6 to 61 years (mean age: 34. 2years), and the distribution of age of onsets was from 2 to 52 years(mean age of onset' 23. lyears). 2) Four cases had family history of porokeratosis, but linear forms did not. 3) Nine cases had pruritus especially, all cases of DSAP and DSP except 1 case complained pruritus. 4) Tmo cases of DSAP had tendency of summer exacerbations. 2. Histopathological results 1) Cornoid lamellae were prominent in all cases of plaque types and linear types, and minimal in all cases of DSAP and DSP except 1 case. 2) Epidermis between the cornoid lamellae were normal or acanthotic in all cases except 1 case of plaque types and linear types, and were atrophic in 5 cases of 8 cases in DSAP and DSP.
Age Distribution ; Age of Onset ; Epidermis ; Female ; Humans ; Male ; Porokeratosis* ; Pruritus ; Sex Ratio

No abstract available.
Animals ; Heterografts* ; Humans* ; Interferon-alpha* ; Melanoma* ; Mice ; Mice, Nude*

We reviewed the clinical features and the skin biopsy slides of 27 patients who were diagnosed as PLEVA clinically or histapathologically in order to evaluate the clinical characteristics and the specific histopathological findings of PLEVA. The results were as follows : l. 13 of these 27 cases(48%) were confirmed as PLEVA. 2. PLEVA was more frequent in males(85% ), most of whom were young adults. 3. In most cases of PLEVA, the predilection site was on the trunk and extremities, and mild pruritus was a characteristic complaint. 4. Most cases of PLEVA were treated with tetracycline or PUVA therapy with temporary remission, but this therapy did not decrease the rate of recurrence. 5. Some histopathological findings previously described as typical in PLEVA(eg, trapped RBC in the epidermis, exocytosis of lymphocyte, dermal hernorrhage and lymphocytic perivasculitis) seemed not to be specific and were often seen in a variety of other dermatoses. 6. The histopathological findings of linear parakeratosis(85%) and dyskeratotic cells in the middle and upper epidermis(92% ) seemed to be significant findings for PLEUA. 7. The above mentioned histopat,hological findings for PLEVA were frequently found from the vesicular lesions or necrotic hemorrhagic papules.
Biopsy ; Epidermis ; Exocytosis ; Extremities ; Humans ; Lymphocytes ; Pityriasis Lichenoides* ; Pityriasis* ; Pruritus ; PUVA Therapy ; Recurrence ; Skin ; Skin Diseases ; Tetracycline ; Young Adult

PURPOSE: The specific aims of the present study were to compare Kirogi children's mental distress and psychosocial factors between short-term (ST) and long-term groups (LT), and to identify predictors of mental distress in the two groups. METHODS: A sample of 107 Kirogi children living in the U.S. participated in this cross-sectional study and completed the following questionnaires: Center for Epidemiologic Studies Depression Scale, State-Trait Anxiety Inventory for Children, Somatic Symptom Scale, Self-Esteem Scale, Parent-Child (P-C) Relationship Satisfaction Scale, Parent-Adolescent Communication Inventory Social, Attitudinal, Familial, and Environmental Scale, and Social Support Scale. RESULTS: The LT group reported higher scores on depression and anxiety, and lower scores on self-esteem and P-C relationship than the ST group. Higher scores on somatic symptoms were found in the ST group. Problematic mother-child communication and dissatisfaction with father-child relationship were significant predictors for mental distress. Self-esteem predicted depression and anxiety in the ST group; particularly self-esteem was a significant predictor for anxiety in both groups. Discrimination and process-oriented stress were significant predictors for depression and anxiety in the ST group. CONCLUSION: Results of the present study reveal the needs for school-based mental health programs for the increasing number of Kirogi children vulnerable to mental distress.
Adolescent ; Anxiety ; Anxiety Disorders ; Child* ; Cross-Sectional Studies ; Depression ; Discrimination (Psychology) ; Father-Child Relations ; Humans ; Mental Health ; Parent-Child Relations ; Psychology ; Surveys and Questionnaires

No abstract available.
Female ; Humans ; Pregnancy ; Pregnancy Trimester, Second*

No abstract available.
Holoprosencephaly* ; Prune Belly Syndrome*

True cysts of the pancreas are rare, and enterogeous (duplication) cysts are extremely rare. We describe a case of enterogenous cyst of the pancreas located in the retroperitoneum, in which homogenous low attenua-tion, multiloculation, internal septation and cyst wall calcification were noted.
Pancreas*

We reported a case of cutaneous focal mucinosis in a 19 year-old male, which occured by multiple nodules on the both dorsa of hands, extensor surface of elbows, intergluteal folds and shins, and responded well to intralesional injection of triamcinolon acetonide. Histopathologically, most of the collagen in the dermis is replaced to homogeneous mucinous material which was confirmed as hyaluronic acid.
Collagen ; Dermis ; Elbow ; Hand ; Humans ; Hyaluronic Acid ; Injections, Intralesional ; Male ; Mucinoses* ; Mucins ; Young Adult

No abstract available.
Bile Ducts* ; Bile* ; Choledochal Cyst*