1.Acantholysis Induction in Skin Explant Cultures Using Drugs ( d - penicillamine , rifampicin and captopril ).
Korean Journal of Dermatology 1990;28(5):509-518
No abstract available.
Acantholysis*
;
Captopril*
;
Penicillamine*
;
Rifampin*
;
Skin*
2.Two Cases of Glass Membrame in The Anterior Chamber Caused by Birth Trauma.
Journal of the Korean Ophthalmological Society 1969;10(3):25-27
Authors observed two cases in which the formation of glass-like hyaline membranes in the anterior chamber caused by birth trauma. Case 1 revealed a curtain-like glass membrane in the anterior chamber with a central nubecula corneae of right eye (Fig. 1). Case 2 revealed two paralled glass membranes and its stripes extended across the anterior chamber attached at each extremity to the posterior surface of the cornea (Fig. 2).
Anterior Chamber*
;
Cornea
;
Extremities
;
Glass*
;
Hyalin
;
Membranes
;
Parturition*
4.Endothelium-Dependent Vasodilation Responses in the Patients with Congestive Heart Failure.
Korean Circulation Journal 1998;28(10):1755-1759
BACKGROUND: Many studies reported that endothelium-dependent vasodilator response is impaired in patients with congestive heart failure. But the opposite results also were reported. The aim of this study was to determine the presence of endothelial dysfunction and its characteristics. METHODS AND MATERIALS: Forearm blood flow was measured in 12 patients with congestvie heart failure (7 males and 5 females, mean age 53+/-11 years old) and 10 normal control subjects (5 males and 5 females, mean age 41+/-10 years old) using strain-gauge plethysmography. The endothelium-dependent vasodilators were acetylcholine (7.5, 15, and 30 microgram/min), which uses a pertussis toxin-sensitive signal transduction pathway, and bradykinin (100, 200, and 400 ng/min), which uses a pertussis toxin-insensitive signal transduction pathway to activate nitric oxide production. Sodium nitroprusside (0.8, 1.6, and 3.2 microgram/min) was used as an endothelium-independent vasodilator. All drugs were infused into the brachial artery with random order. RESULTS: The basal forearm blood flow was similar between both groups. The maximum flow in response to acetylcholine, bradykinin, and sodium nitroprusside was also similar in two groups. CONCLUSIONS: Patients with congestive heart failure showed normal endothelium-dependent vasodilator responses to both acetylcholine and to bradykinin. This finding indicates that the endothelial vasodilator function is normal in the patients with heart failure.
Acetylcholine
;
Brachial Artery
;
Bradykinin
;
Endothelium
;
Endothelium-Dependent Relaxing Factors
;
Estrogens, Conjugated (USP)*
;
Female
;
Forearm
;
Heart Failure*
;
Humans
;
Male
;
Nitric Oxide
;
Nitroprusside
;
Plethysmography
;
Signal Transduction
;
Vasodilation*
;
Whooping Cough
6.Significance of p53 overexpression in extrahepatic bile duct cancer.
Sun Hee KIM ; Woo Ho KIM ; Yong Hyun PARK
Journal of the Korean Cancer Association 1993;25(6):873-877
No abstract available.
Bile Ducts, Extrahepatic*
7.Factors Associated with Cancer Screening Rates of Manufacturing Workers.
Su Ho PARK ; Chang Hee KIM ; Eun Kyung KIM
Korean Journal of Occupational Health Nursing 2013;22(3):179-190
PURPOSE: Regular cancer screening for workers can help prevent cancer or allow early treatment, and is thus beneficial in improving health, reducing costs, and increasing companies' productivity. However, there has been little research on cancer screening rates of workers and related factors. The purpose of this study was to identify cancer screening rates and relevant factors among manufacturing workers. METHODS: Using a questionnaire, data were collected from 335 workers aged over 40 years recruited from seven manufacturing companies. The collected information included cancer screenings (stomach, colorectal, breast, and cervical), attitude towards cancer screening, and demographic and job characteristics. RESULTS: 72.5% of workers received stomach cancer screening (SCS), and 43% received colorectal cancer screening (CRCS). Among 86 women, 68.6% received breast cancer screening and cervical cancer screening. The attitude towards cancer screening was 29.5+/-3.78. Workers aged over 51, married, and those working in mobile manufacturing were more likely to have undergone SCS. Workers aged over 51, married, those working in mobile manufacturing, those in workplaces with more than 1,001 employees, and those with more positive attitudes toward cancer screening were more likely to have undergone CRCS. Finally, attitude affected cervical cancer screening. CONCLUSION: Workers in small-sized workplaces had lower cancer screening rates. Thus, follow-up research should assess the health environment of workplaces and develop educational programs on cancer screening that reflect attitudes towards screening.
Aged
;
Breast Neoplasms
;
Colorectal Neoplasms
;
Early Detection of Cancer
;
Efficiency
;
Female
;
Follow-Up Studies
;
Humans
;
Mass Screening
;
Surveys and Questionnaires
;
Stomach Neoplasms
;
Uterine Cervical Neoplasms
8.Effect of Lipopolysaccharide on the Expression of Chemokine Mig Gene in Mouse Peritoneal Macrophages.
Ho Suk DOH ; Sung Kwang KIM ; Hee Sun KIM
Journal of Bacteriology and Virology 2001;31(1):11-20
No abstract available.
Animals
;
Macrophages, Peritoneal*
;
Mice*
9.A Comparison Study of Radiostrontium Chelation with Chitin, Chitosan, EDTA and DTPA.
Hee Seung BOM ; Young Ho KIM ; Ji Yeul KIM
Korean Journal of Nuclear Medicine 1998;32(4):391-395
PURPOSE: Chitin and chitosan are nontoxic natural chelators that chelate radiostrontium effectively. The purpose of this study was to compare radiostrontium chelation of chitin and chitosan with that of well known chemical chelators, namely EDTA and DTPA. MATERIALS AND METHODS: The chelaton rates of chitin, chitosan, EDTA and DTPA were compared using a column chromatography method (Sephadex G-25M, Sweden). Three kinds of chitins and four kinds of chitosans were used. All of them were water soloble. RESULTS: Phosphated chitosan showed the highest chelation yield of more than 97% at pH 7. All of chitins, chitosans, EDTA and DTPA showed chelation yield of more than 90% independent of varing pH level. CONCLUSION: Chitin and chitosan have similar chelation rate as compared with EDTA and DTPA.
Chelating Agents
;
Chitin*
;
Chitosan*
;
Chromatography
;
Edetic Acid*
;
Hydrogen-Ion Concentration
;
Pentetic Acid*
10.Primary Squamous Cell and Adenosquamous Carcinomas of the Stomach: Clinico-pathologic analysis of 6 cases.
Eun Hee SUH ; Woo Ho KIM ; Yong Il KIM
Korean Journal of Pathology 1986;20(1):60-70
Squamous cell carcinomas and adenosquamous carcinomas are rarely originated from the stomach, thus the limited and sporadic informations about their clinico-pathologic characteristics as well as histogenesis have been elucidated. Six cases of primary squamous cell carcinoma (3 cases) and adenosquamous carcinoma(3 cases) in the stomach were examined during a period of 4 years from 1981 to 1984. After pertinent review of both clinical data and morphology through extended histotopographic study performed on 4 cases, their clinicopathologic characteristics were described. Male to female sex ratio was 4 : 2 and average age was 58.6 years. Clinical presentations or physical findings were not different from those of adenocarcinoma. Tumor masses of all cases were located in the body or phloric antrum. In all cases except for the early gastric carcinoma, each tumor was larger than 8 cm in long axis, and showed expansile and intraluminal endophytic growing tendencies with sharp margin. Simple Borrmann's macroscopic classification was applicable to none of 6 cases because of irregular and multicentric ulceration pattern and occasional submucosal growth which were reminiscent of those in submucosal tumors such as malignant lymphoma and leiomyosarcoma. Virtually four out of all six cases were diagnosed as submucosal tumor at the time of radiological examination. Microscopically three cases were composed of pure squamous cell carcinoma and remaining three contained both adeno and squamous components. Metastatic regional lymph nodes revealed only squamous element in case of pure squamous cell carcinoam, while both components were identified in adenosquamous carcinomas. Surrounding non-tumors mucosa exhibited moderate to severe degree of intestinal metaplasia accompanied by multifocal mucin pool formation. Growth pattern and surrounding mucosal changes as with older age prevalence of these tumors might express the biological behavior of intestinal type of gastric carcinoma.
Female
;
Male
;
Humans
;
Neoplasm Metastasis