OBJECTIVE: The purpose of this present study was to compare mouse embryo development in 3 commercial media and hatching competence of mouse embryo with or without enzymatic treatment. METHODS: Collected 375 mouse embryos were divided into three groups, and then cultured in IVF-20 (G2), Medicult IVF (M3), P-1 (blastocyst M), respectively. Three day mouse morulae were cultured in G2 media treated with pronase. The results were analyzed using Chi-square test, and considered statistically significant when p<0.01. RESULTS: The developmental rate of 2 cell mouse embryo after 72 hours was highest in IVF-20 (G2) among conventional 3 media. The hatching rate of mouse morulae was low when clultured in G2 media without pronase during 48 hours. However, it was higher when cultured in media treated with l mg/ml, 2.5 mg/ml, 5 mg/ml pronase, respectively. CONCLUSIONS: Using good media and digestion of zona pellucida with enzymatic treatment improve development and hatching rate of embryo. Therefore, implantation and pregnancy rate could be improved.
Animals ; Digestion ; Embryonic Development ; Embryonic Structures* ; Female ; Mental Competency ; Mice* ; Morula ; Pregnancy ; Pregnancy Rate ; Pronase* ; Zona Pellucida

No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

No abstract available.
Lichens* ; Mucinosis, Follicular*

No abstract available.
Thioacetamide*

No abstract available.
Nocardia Infections*

PURPOSE: World wide studies have reported many cases of the normal variants of the hepatic artery in healthy individuals. Unfortunately, there are few medical reports in Korea, this study presents the results and analysis of the anatomical variants in the hepatic artery. METHODS: This study analyzed the blood supply of the liver in 131 patients who had received hepatic angiography and superior mesenteric angiography from January 1996 to September 2003 at the Maryknoll general hospital. RESULTS: The hepatic artery pattern with a normal hepatic artery pattern was observed in 101 out of 131 cases (77.1%) ; the right and left hepatic arteries arising from the proper hepatic artery, which arising from the common hepatic artery. The normal variations in the hepatic artery pattern were observed in 30 out of 131 cases (22.9%) ; the replaced right hepatic artery arising from the superior mesenteric artery was observed in 14 out of 131 cases (10.7%). The replaced left hepatic artery arising from the left gastric artery was observed in 6 out of 131 cases (4.6%). The common hepatic artery arising from the superior mesenteric artery was noted in 4 out of 131 cases (3.1%). The accessory left hepatic artery arising from the left gastric artery was observed in 1 out of 67 cases (0.7%). Other variants were noted 5 out of 131 cases (3.8%). CONCLUSION: Knowledge of the patterns and frequency of the variants in hepatic artery is increasing with the larger number of national reports on the hepatic artery variants, which can be great help in surgical operations, hepatic arterial embolization, or liver transplant.
Angiography ; Arteries ; Hepatic Artery* ; Hospitals, General ; Humans ; Korea ; Liver ; Mesenteric Artery, Superior

No abstract available.
Indocyanine Green* ; Skin*

Background: To evaluate the drug prescription patterns for men diagnosed with benign prostatic hyperplasia (BPH) in Korea. Methods: We extracted the data of 3% of the national patient samples including men aged ≥ 40 years between 2012 and 2017 from the Health Insurance Review and Assessment database and investigated the drugs prescribed for men with the BPH code N40. Men with a diagnosis of BPH but not receiving treatment were excluded. The primary outcome was the drugs prescribed and the changes in drug prescription pattern over 6 years for men first diagnosed with BPH. Results: Alpha blockers were the most commonly prescribed drugs in men with BPH, and tamsulosin was the most common. The proportion of prescriptions increased steadily. The number of prescriptions for anticholinergics (ACH) increased, but decreased with the start of mirabegron prescriptions in 2015. Prescriptions of mirabegron are increasing rapidly and replacing ACH. Based on the prescription pattern by drug category, alpha blocker monotherapy decreased, whereas combination therapies such as alpha blocker + 5-alphareductase inhibitors (5ARI), and alpha blocker + 5ARI + ACH increased steadily. As for the number of prescriptions by drug ingredient, tamsulosin monotherapy was the most common, and the combination therapy of tamsulosin and mirabegron increased. Conclusion Alpha blockers were the most commonly prescribed drug for men first diagnosed with BPH in Korea from 2012 to 2017, and tamsulosin was the most common alpha blocker. Prescriptions of combination therapy and mirabegron are gradually increasing.

To evaulate the closure and recurrence rate of laser treatment for juxtafoveal and extrafoveal CNV with well-defined boundary, we studied 15 eyes of 15 patients that could be followed up for at least 1 year. The follow-up ranged form 12 to 31 months(mean, 17.1 months). Three and six weeks after laser treatment, all neovascularization was obliterated. Eight months, after laserphotocoagulation was obliterated. Eight months, after laser photocoagulation there was one recurrence in juxtafoveal CNV. In7 of 10 laser-treated eyes in classic, extrafoveal CNV, visual or more in three eyes. Of 5 laser-treated eyes in classic, juxtafoveal CNV, visual acuity had changed by no more than 2 lines in 3 eyes and decreased by 2 or more lines in 2 eyes. The short-term results of laser treatment for classic CNV were good, but long-term evaluation is required.
Choroid* ; Choroidal Neovascularization* ; Follow-Up Studies ; Humans ; Light Coagulation* ; Recurrence ; Visual Acuity

No abstract available.
Child* ; Humans ; Syringoma* ; Vulva