1.Traumatic Spondylolisthesis of the Axis
Myung Sang MOON ; In Young OK ; Suk Whan SONG ; Hee Gon KIM
The Journal of the Korean Orthopaedic Association 1986;21(6):1126-1132
Twelve patient with fracture of the neural arch of the axis (hangman's fracture or traumatic spondylolisthesis of the axis) were treated at Kangnam St. Mary's Hospital between 1980 and 1986. There were three type I fractures, seven type II fractures, and two type III fracture. Non of these patients had neurological damage. Seven patients (five in type II and two in type III) in this series, underwent anterior interbody fusion operation between axis and third cervical vertebra following 6 weeks of cervical traction. The remaining five patients were treated conservatively by cervicel traction in the bed. Average follow up period was 24 months. The mean duration of fracture union was 10 weeks after trauma in 3 cases of type I and twelve weeks after trauma in 2 cases of type II which were treated conservatively. Otherwise in 5 cases of type II and two cases of type III which were taken anterior interbody fu sion, the mean duration of fracture union was 8 weeks in type II and 10 weeks in type III after surgery. All regained a stability of the cervical spines. Because the fracture healing of the neural arch invariably occurred through this study, it is felt that anterior interbody fusion between axis and third cervical vertebra is necessary surgical.procedure to gain the early stability if there is an evidence of persistant instability between axis and third cervical verbebrae even after 6 weeks of conservative traction treatment.
Follow-Up Studies
;
Fracture Healing
;
Humans
;
Spine
;
Spondylolisthesis
;
Traction
2.A Case of Syphilitic Aortitis with Aortic Insufficiency and Aortic Aneurysm.
Jae Myeung KANG ; Yang Soo KIM ; Jun Hee WOO ; Ji So RYU ; Hee Gon SONG ; Seung Whan LEE ; Myeong Kun SONG ; Kwang Sun MIN ; Sang Sik CHUNG
Korean Journal of Infectious Diseases 2000;32(5):402-406
Syphilitic aortitis, passing out of our mind, is the most common systemic manifestation of late syphilis and is more typically manifestated 10 to 30 years afterward. This diagnosis has been made less frequently in recent decades than in the past, because of public awareness of syphilis and screening program. Treponema pallidum lodge within vasa vasorum, especially ascending aorta cause the histologic changes, which are responsible for the three major forms of symptomatic cardiovascular syphilis, including aortic insufficiency, coronary ostial stenosis, and aortic aneurysm. We experienced a case of syphilitic aortitis with aortic insufficiency and aortic aneurysm in a 48-year-old man presented with progressive dyspnea. Echocardiography, chest CT, and later surgical correction were performed and surgical specimen revealed the histologic finding consistent with syphilitic aortitis. We report this case with a review of the literature.
Aorta
;
Aortic Aneurysm*
;
Aortitis
;
Constriction, Pathologic
;
Diagnosis
;
Dyspnea
;
Echocardiography
;
Humans
;
Mass Screening
;
Middle Aged
;
Syphilis
;
Syphilis, Cardiovascular*
;
Tomography, X-Ray Computed
;
Treponema pallidum
;
Vasa Vasorum
3.Evaluation of Enterococcus faecalis removal efficacy of the EndoVac(R) and EndoActivator(R) intracanal irrigation methods.
Seung Gon SONG ; Se Hee PARK ; Kyung Mo CHO ; Jin Woo KIM
Journal of Korean Academy of Conservative Dentistry 2009;34(5):390-396
The aim of this study was to evaluate endodontic irrigation methods with EndoVac(R) and EndoActivator(R) in the elimination of Enterococcus faecalis from the root canals. Extracted 70 human single-rooted teeth were used. The canals were instrumented by a crown-down technique with .04 taper ProFile to ISO size 40. After the teeth were autoclaved, the canals were inoculated with E. faecalis and incubated for 48 h. The teeth were randomly divided into three experimental groups of 20 teeth each according to canal irrigation methods and two control groups as follows: group 1 - EndoVac(R) group 2 - EndoActivator(R) ; group 3 - Conventional needle irrigation method. After canal irrigation using 2.5% NaOCl, first samples (S1) were taken using sterile paper point. And the canals were filled with sterile brain heart infusion (BHI) broth and incubated for 24 h, then second samples (S2) were taken. The samples were cultured on BHI agar plate to determine the numbers of colony forming units (CFU). In first sampling (S1), only one canal of conventional method among the all experimental groups was positive cultured. In second sampling (S2), EndoVac(R) group showed the least positive culture numbers of E. faecalis. There was statistically significant difference between the EndoVac(R) and conventional needle irrigation methods in the mean value of Log CFU. According to the results of this study, EndoVac(R) showed better efficacy than conventional needle irrigation method in the elimination of E. faecalis from the root canal.
Agar
;
Brain
;
Dental Pulp Cavity
;
Enterococcus
;
Enterococcus faecalis
;
Heart
;
Humans
;
Needles
;
Stem Cells
;
Tooth
4.Efficacy of Repeated Arterial Infusion of Cisplatin and 5-Fluorouracil via a Percutaneously Implantable Port System in Advanced Hepatocellular Carcinoma.
Hee Gon SONG ; Han Chu LEE ; Byung Cheol SONG ; Young Hwa CHUNG ; Yung Sang LEE ; Hyun Ki YOON ; Kyu Bo SUNG ; Dong Jin SUH
The Korean Journal of Hepatology 2001;7(1):61-67
BACKGROUND/AIMS: A prospective study was performed to evaluate the efficacy of low dose administration of cisplatin (CDDP) and 5-fluorouracil (5-FU) by repeated arterial infusion via a percutaneously implantable port system (PIPS) for advanced hepatocellular carcinoma (phase II trial). METHODS: Ten patients with hepatocellular carcinoma belonging to TNM stage IV, but without extrahepatic spread, were enrolled. Nine patients had main portal vein thrombosis. All the patients were positive for HBsAg. Patients were repeatedly treated with an arterial infusion of CDDP and 5-FU (10 mg and 250 mg, respectively, for 5 hours on days 1-5) via a PIPS at four week intervals. The response was assessed by dynamic CT after two courses of chemotherapy. RESULTS: Insertion of PIPS was successful in 8 of 10 patients. Two patients could not receive a second course of chemotherapy because one died of progressive hepatic failure and the other developed local infection and pseudoaneurysm formation. All the remaining 6 patients exhibited tumor progression after two courses of chemotherapy. The median survival time was 89 days (range, 59-204). The causes of death were progressive hepatic failure in one patient and uncontrolled esophageal variceal bleeding in one patient. CONCLUSIONS: Arterial infusion chemotherapy with CDDP and 5-FU via a PIPS was not an effective treatment for patients with advanced hepatocellular carcinoma.
Aneurysm, False
;
Carcinoma, Hepatocellular*
;
Cause of Death
;
Cisplatin*
;
Drug Therapy
;
Esophageal and Gastric Varices
;
Fluorouracil*
;
Hepatitis B Surface Antigens
;
Humans
;
Liver Failure
;
Prospective Studies
;
Venous Thrombosis
5.Alpha Stent for Coiling of Unruptured, Wide-Necked, Distal Internal Carotid Artery Aneurysms: Safety and Effectiveness at 6 Months
Yunsun SONG ; Jae Jon SHEEN ; Joong Goo KIM ; Sang Hun LEE ; Su Hee CHO ; Jung Cheol PARK ; Choong Gon CHOI ; Deok Hee LEE
Korean Journal of Radiology 2020;21(2):228-235
6.Efficacy of early steroid use in Mycoplasma pneumoniae pneumonia.
Hee Seong KIM ; Myung Gon SONG ; Yong Wook KIM ; Kyoung Sim KIM ; Eun Young KIM ; Young KIM ; Hae In JANG ; Hyung Min CHO
Allergy, Asthma & Respiratory Disease 2017;5(5):280-286
PURPOSE: The aim of this study was to evaluate whether or not the early use of steroid is useful for treating Mycoplasma pneumoniae pneumonia. METHODS: A prospective study was conducted on 85 patients with M. pneumoniae pneumonia admitted to Gwangju Christian Hospital between September 2015 and April 2016. A total of 85 patients were enrolled. Of these, 33 were treated with steroids (methyl-prednisolone 1 mg/kg/day), while 52 were not; both were treated with macrolides. The overall duration of fever was compared between the 2 groups and findings on chest radiographs were evaluated for their deterioration. RESULTS: The duration of fever after admission (1.36±0.92 days vs. 2.17±1.30 days, P=0.003) and the overall duration of fever (4.42±2.13 days vs. 6.07±2.59 days, P=0.003) were significantly lower in the steroid group. The duration of fever before admission was not different between the steroid and macrolide groups (3.06±1.74 days vs. 3.90±2.21 days, P=0.068). On chest radiographs taken 3 days later, 1 of 33 patients in the steroid group and 5 of 50 patients in the macrolide group worsened, although there was no statistically significant difference between the 2 groups (P=0.395). There was no significant difference in the duration of hospitalization between the 2 groups (6.72±1.54 days vs. 6.92±1.87 days, P=0.618). CONCLUSION: Early administration of steroids on patients with M. pneumoniae pneumonia reduced the duration of fever, but there was no difference in duration of admission and x-ray deterioration.
Fever
;
Gwangju
;
Hospitalization
;
Humans
;
Macrolides
;
Mycoplasma pneumoniae*
;
Mycoplasma*
;
Pneumonia*
;
Pneumonia, Mycoplasma*
;
Prospective Studies
;
Radiography, Thoracic
;
Steroids
7.Empyema and Pericarditis by Salmonella Group D Complicating Malignant Thymoma with Pleural Metastasis: A case report.
Deog Gon CHO ; Min Seop JO ; Kyu Do CHO ; So Hyang SONG ; Chi Hong KIM ; Sun Hee LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2004;37(4):382-385
Non-typhoid salmonella infection frequently associated with bacteremia has rarely been reported in immunocompromized patients with malignant neoplasms, diabetes or extended use of corticosteroids. Especially, concomitant pleural empyema and pericarditis due to non-typhoid salmonella infection is extremely rare. Here, we report a case of concomitant empyema and pericarditis in malignant thymoma with pleural metastasis complicated by salmonella group D infection with brief review of literature.
Adrenal Cortex Hormones
;
Bacteremia
;
Empyema*
;
Empyema, Pleural
;
Humans
;
Neoplasm Metastasis*
;
Pericarditis*
;
Salmonella Infections
;
Salmonella*
;
Thymoma*
8.The mRNA Expression of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) and Its Receptors in Hepatocellular Carcinoma and Surrounding Liver Tissues.
Saera JUNG ; Han Chu LEE ; Hee Gon SONG ; Young Hwa CHUNG ; Yung Sang LEE ; Ghil Sook YOON ; Eunsil YU ; Dong Jin SUH
The Korean Journal of Hepatology 2001;7(3):273-280
BACKGROUND/AIMS: TRAIL-induced apoptosis was believed to occur in tumor cell lines, while not in normal cells, which suggested that TRAIL might be safe as an antitumor therapy. Some authors advocate that this exclusive TRAIL-induced apoptosis depended on whether or not TRAIL-R3 mRNA was expressed. In this study we investigated the difference in the expression of TRAIL and its receptors mRNA between human hepatocellular carcinoma (HCC) and surrounding liver tissues. METHODS: Intra-operative sampling of HCC and paired surrounding liver tissue was performed in 12 patients who underwent hepatic resection due to HCC. After RT-PCR, using total RNA extracts from the tissues, amplified RT-PCR, products were analyzed qualitatively for the expression of TRAIL and its receptors mRNA. Both tissues were compared semi-quantitatively for the expression of TRAIL-R3 mRNA with beta-actin using the method of Nicoletti et al. RESULTS: 1) TRAIL mRNA was expressed in HCC and surrounding liver tissues in all cases. 2) TRAIL-R1, -R2, and -R3 mRNA were also expressed in HCC and surrounding liver tissues in all cases. 3) The ratio of the expression of TRAIL-R3 mRNA to beta-actin mRNA was 0.22+/-0.15 in HCC and 0.34+/-0.21 in surrounding liver tissues (p=0.124, paired t-test). 4) TRAIL, TRAIL-R1, -R2 and -R3 mRNA were expressed in all HCC cases irrespective of the degree of tumor cell differentiation. CONCLUSIONS: TRAIL, TRAIL-R1, -R2, and TRAIL-R3 mRNA were expressed in all of the HCC and surrounding liver tissues. There was no quantitative difference in the expression of TRAIL-R3 mRNA between both tissues.
Actins
;
Apoptosis
;
Carcinoma, Hepatocellular*
;
Cell Differentiation
;
Cell Line, Tumor
;
Humans
;
Liver*
;
Necrosis*
;
RNA
;
RNA, Messenger*
;
TNF-Related Apoptosis-Inducing Ligand
9.Two Cases of Fatal Hypoxemia after Talc Pleurodesis for Recurrent Malignant Pleural Effusion.
Shin Ae PARK ; Han Hee LEE ; Dae Jun KIM ; Byoung Yong SHIM ; So Hyang SONG ; Chi Hong KIM ; Myeong Im AHN ; Deog Gon CHO ; Kyu Do CHO ; Hoon Kyo KIM
Tuberculosis and Respiratory Diseases 2007;62(3):217-222
Talc pleurodesis is a safe and effective treatment for a recurrent malignant pleural effusion. However, acute hypoxemia, pulmonary edema or acute respiratory failure can develop in a small number of patients. We report 2 patients who developed fatal hypoxemia after talc pleurodesis which was necessary the control recurrent pleural effusion. The first case was an 18-year old male diagnosed with Ewing's sarcoma with bilateral lung metastases and pleural effusion. The performance status was ECOG (Eastern Cooperative Foncology Group) grade 3. Fever along with hypoxemia and leukocytosis developed 10 hours after the second talc pleurodesis on the right side for an uncontrolled pleural effusion, The patient died from respiratory failure after 13 days. The second case was a 66-year old female diagnosed with non-small cell lung cancer with a bone metastasis. Two weeks after systemic chemotherapy, she complained of dyspnea, and a pleural effusion was observed on the right side. Her performance status was ECOG grade 3. Talc pleurodesis was performed for recurrent pleural effusion, but hypoxemia developed 6 days after pleurodesis and she died from respiratory failure 10 days after pleurodesis. In conclusion, talc pleurodesis should be performed very carefully in patients with a poor performance status, in cases with repeated pleurodesis, bilateral pleural effusion, recent chemotherapy, radiotherapy and when there are parenchymal metastatic lesions present.
Adolescent
;
Aged
;
Anoxia*
;
Carcinoma, Non-Small-Cell Lung
;
Drug Therapy
;
Dyspnea
;
Female
;
Fever
;
Humans
;
Leukocytosis
;
Lung
;
Male
;
Neoplasm Metastasis
;
Pleural Effusion
;
Pleural Effusion, Malignant*
;
Pleurodesis*
;
Pulmonary Edema
;
Radiotherapy
;
Respiratory Insufficiency
;
Sarcoma, Ewing
;
Talc*
10.Diagnostic Patterns and Medical Costs in the Evaluation of Syncope Patients Visiting an Emergency Department.
Hee YOON ; Ji Ung NA ; Tae Gun SHIN ; Min Seob SIM ; Ik Joon JO ; Hyoung Gon SONG ; June Soo KIM
Journal of the Korean Society of Emergency Medicine 2011;22(6):662-668
PURPOSE: Syncope is a common clinical problem. However, diagnosis of the cause of syncope is not simple due to a wide variety of forms of syncope. The aim of this study was to assess current diagnostic methods and the associated medical costs which accompany the evaluation of patients suffering syncope who admitted to an emergency department (ED). METHODS: This study is a prospective, observational, single center study. Patients included in the study visited the ED of a single, tertiary hospital between January and December 2009, and were diagnosed with syncope. We investigated the diagnostic yields (DY) for the tests that were employed and evaluated factors related to medical costs. RESULTS: A total of 124 patients were enrolled in this study. Blood tests, chest radiography, postural blood pressure (BP) measurement and computerized tomography of the brain were performed in over 60% of cases, but DY for each of these tests was less than 3%, except for postural BP measurement (7.4%). The test which demonstrated a relatively high DY was the head-up tilt test (68.1%). The ratio of the cost of each test among the total medical costs required by all patients (constituent ratio) was highest for brain imaging tests (12.2%). The total cost of syncope evaluation per patient was 1,454,000+/-2,865,000 won. Factors including hospital admission and diagnosis of cardiac syncope resulted in significantly higher total medical costs for those patients. CONCLUSION: Among the tests performed in the ED for syncope evaluation, blood tests, chest x-ray and brain imaging tests were commonly used but resulted in relatively low diagnostic yield. Independent factors which increased medical costs were hospital admission and diagnosis of cardiac syncope.
Blood Pressure
;
Brain
;
Emergencies
;
Hematologic Tests
;
Humans
;
Neuroimaging
;
Prospective Studies
;
Stress, Psychological
;
Syncope
;
Tertiary Care Centers
;
Thorax