1.Epidermiologic Study of Possible Korean Plants Involved in Contact Dermatitis.
Hee Chul EUN ; Maun Gil KIM ; Soo Nam KIM
Korean Journal of Dermatology 1979;17(4):265-282
Plant dermatitis can be classified as primary irritant dermatitis, allergic contact dermatitis, phytophotodermatitis and pseudophytophotodermatitis. Among these, allergic contact dermatitis is seen most freguently. It is generally known that dermatitis causing plants have various characteristics depending on the habitat af different plants. Until now we have had great difficulty in finding the causative factors in plant dermatitis in Korea. This is due to the fact that we do not have anr comprehensive reports regarding domestic or imported timbers concerned in contact dermatiti. The purpose of this thesis is to gather the basic materials necessary to discover the cauae of plant contact dermatitis. All kinds of trees, flowers, and grasses in Korea and imported timbers concerned with contact dermatitis were considered in this study. We strove to ascertain whether the species in our country are the same as found in foreign countries or other different speceies are in our country under the sarne genus found in foreign countries. The basis for our study is several Korean plant books as well as interviews with several native botanists. Vie also discussed major families af plants causing or possible causing plant dermatitis in Korea.
Dermatitis
;
Dermatitis, Allergic Contact
;
Dermatitis, Contact*
;
Dermatitis, Irritant
;
Ecosystem
;
Flowers
;
Humans
;
Korea
;
Plants
;
Poaceae
;
Trees
2.An Immunohistochemical Study of PNA (peaunt agglutinin) Binding in Transitional Cell Carcinomas of the Urinary Bladder.
Chul Hwan KIM ; Nam Hee WON ; Kap No LEE
Korean Journal of Pathology 1990;24(3):227-235
Recently, extensive uses of lectins as cytochemical markers have made of studies for various epithelial and nonepithelial neoplasia, however, investigations of epithelial cell surface of transitional cell carcinomas of the urinary bladder have been few. Thus, the atuhors performed a study of PNA binding in the authors performed a study of PNA binding in transitional cell carcinomas with comparision with that in normal mucosa of the urinary bladder to allow more accurate diagnosis and histological grade or degree of differentiation. The results of this study are as follows: 1) PNA shows negative reactions on all ten normal mucosae of the urinary bladder but positive staining at the glycocalyx of umbrellar cells in two cases. 2) PNA shows negative reactions on all four cases of von Brun'n nests and cystitis cystica. 3) PNA shows positive reactions on thirty (50%) of total sixty-one cases of transitional cell carcinomas and reveals two (20%), nine (41%), eleven (55%) and eight (88%) cases in grade I, II, III and IV, respectively. 4) PNA shows positive reactions on the intracytoplasm and/or degree of PNA binding activity in grade I to IV transitional cell carcinomas is not statistically significantly different (p>0.05). In summary, PNA did not react with normal nucosa and metaplastic lesions such as von Brunn's nests and cystitis cystica, however, it reacted with 50% (30/61 cases) of transitional cell carcinoma and its positivity is significantly increased with gradings of transitional cell carcinomas (p<0.05).
3.Chronic obstructive pulmonary disease: association with gastroesophageal reflux disease.
Young Chul KIM ; Jae Hee OH ; Joo Nam BYUN
Journal of the Korean Radiological Society 1992;28(5):715-723
Multiple factors including gastroesophageal reflux disease (GERD) were evaluated for a case-control study in Chonnam area to investigate the causative entity of COPD. Data on the multiple causative factors from hospital records and interview survey were analyzed in three groups of COPD(64 cases as case group), normal lung (83 cases as control group 1) and non-COPD lung disease (45 cases as control group 2). Smoking status, history of adulthood pulmonary infection and frequent history of URI, socioeconomic status, and GERD were significantly different between COPD group and control group 1. Drinking status, physical height of the subjects and GERD were significantly different between COPD group and control group 2. If control group 1 was used, odds ratio of GERD and COPD was 5.68(95%confidence interval, 95% CI:2.59-12.45) and 4.81 (95% CI:1.89-10.53) when adjusted by age and smoking status. If control group 2 was used. Odds ratio of GERD and COPD was 4.22 (95% CI:1.69-10.56) and 4.59 (95% CI:1.64-12.86) when adjusted by alcohol and adulthood respiratory infection status. In summary, there results suggested that GERD might play a causative role in the development of COPD.
Case-Control Studies
;
Drinking
;
Gastroesophageal Reflux*
;
Hospital Records
;
Jeollanam-do
;
Lung
;
Lung Diseases
;
Odds Ratio
;
Pulmonary Disease, Chronic Obstructive*
;
Smoke
;
Smoking
;
Social Class
4.A Case of Unilateral Nevoid Telangiectasia.
Chang Hun AHN ; Ki Heum NAM ; Hee Chul EUN ; Soo Nam KIM
Korean Journal of Dermatology 1981;19(4):405-409
The brief report of Zeisler (1922) of a pregnant woman with scattered telangiectasia in a unilateral distribution is perhaps the first recorded case of this syndrome. The syndrome has been described in association with pregnancy, puberty, alcoholisrn and cirrhosis, hormonal therapy and congenital status. The authors observed in a 17-year-old male unilateral telangiectatic lesions over the left C, C, C, Tl and T, dermatomal regions. The lesions developed at first at his puberty on the anterior part of the chest as speckled bright red discoloration. Thereafter, the lesion has been progressed to involve the left upper extremity, sholder, upper middle part of the chest, eventually. Family history was negative and physical, lahoratory and X-ray examination were all negative or within normal limit. No mucous membrane involvement was observed. On histopathologic examination of the skin lesion, thin walled ectatic vessels lined with single layer of endothelial cells were observed in the upper dermis. The lesions were partly dermabrased with favorable result.
Adolescent
;
Dermis
;
Endothelial Cells
;
Female
;
Fibrosis
;
Humans
;
Male
;
Mucous Membrane
;
Pregnancy
;
Pregnant Women
;
Puberty
;
Skin
;
Telangiectasis*
;
Thorax
;
Upper Extremity
5.Contact Dermatitis due to Stearic Acid in Eye Cosmetics.
Young Chul KYE ; Yong Sang KIM ; Hee Chul EUN ; Soo Nam KIM
Korean Journal of Dermatology 1982;20(4):583-587
Cosmetic dermatitis of the eyelids may be caused not only by eye make-up but also by cosmetics used elsewhere and conveyed by the fingers to the eyelids. The thin skin of the eyelid is highly susceptible to contact dermatitis, particularly from cosrnetics. A 28 year old female was reported to have contact dermatitis caused by stearic acid in eye cosmetics. The skin lesiens of this patient showed erythematous, edematous, vesicular ruptions on both the upper and lower eyelids. The patch test results were positive for both cornmercial eyeliner and fluid mascara on the second and fourth day. Many of all the ingredients in the eyeliner and fluid mascara, only stearic acid gave positive result on patch tests.
Adult
;
Dermatitis
;
Dermatitis, Contact*
;
Eyelids
;
Female
;
Fingers
;
Humans
;
Patch Tests
;
Skin
6.Efficacy of Clozapine on Schizophrenia with Polydipsia: Two Cases Experience.
Chul Eung KIM ; Nam Jun PARK ; Min Hee KANG ; Jae Nam BAE
Korean Journal of Psychopharmacology 2003;14(1):63-66
Polydipsia occurs frequently in chronic schizophrenic patients, some of whom develop hyponatremia. Although the underlying pathophysiology of polydipsia among psychiatric patients, recent reports indicate that clozapine treatment improves polydipsia-hyponatremia in schizophrenia. Two schizophrenic patients with polydipsia, followed for more than two years, showed improvement on clozapine. Case 1 was a patient without history of hyponatremia who improved from polydipsia and psychosis. Case 2 was an inpatient with polydipsia and hyponatremia who showed improvement of polydipsia and did nor recur hyponatremia. The limited information provided by these case reports suggest the need for controlled studies of the clozapine effect on schizophrenic patients with polydipsia.
Clozapine*
;
Humans
;
Hyponatremia
;
Inpatients
;
Polydipsia*
;
Psychotic Disorders
;
Schizophrenia*
7.A Case Combined Germ Cell Tumor in Testis.
Hae Joo NAM ; Won Hee CHOI ; Tae Sook LEE ; Jun Gyu SUH ; Kyung Chul LEE
Yeungnam University Journal of Medicine 1985;2(1):293-297
Primary germ cell tumor of the testis is rare, which occupies 1 to 2% of all reported malignant male neoplasms. Combined primary germ cell tumor of the testis composed of embryonal carcinoma and seminoma is more rare tumor. The authors experienced a case of 50-year old male who presented with painless enlargement of right testicle. He has had radical orchiectomy and diagnosed by pathologically as combined germ cell tumor of testis. The testicle is measuring 180 gm in weight and 9×6×5 cm in dimension, and almostly replaced by tumor mass. Grossly the tumor is rubbery solid smooth tumor mass, with variegated cut surface with geographically outlined diffuse necrotic area. Histologically the tumor is composed of two components of tumor, which are solid growth pattern of large round to polyhedral cells with clear or granular cytoplasm and distinct cell border, and anastomosing glandular and papillary arrangement of anaplastic epithelial cells. The former corresponds to seminoma, and the latter to embryonal carcinoma. Each tumor lobule is separated by abundant fibrous stroma.
Carcinoma, Embryonal
;
Cytoplasm
;
Epithelial Cells
;
Germ Cells*
;
Humans
;
Male
;
Neoplasms, Germ Cell and Embryonal*
;
Orchiectomy
;
Seminoma
;
Testis*
8.A Case of Cerebral Metastsis Secondary to Primary Epithelial OvarianCarcinoma : in Complete Responder to Chemotherapy and Surgery.
Korean Journal of Obstetrics and Gynecology 1997;40(3):675-680
Cerebral metastses secondary to primary epithelial ovarian carcinoma are unusual. The incidence was estimated under 1%, but some authors reported higher incidence than previously reported data. Recently, we experienced a case of cerebral metastasis secondary to primary epithelial ovarian cancer. We present this case with review of brief related literatures.
Drug Therapy*
;
Incidence
;
Neoplasm Metastasis
;
Ovarian Neoplasms
9.Unmet dental care needs according to employment status.
Jeong Hee KANG ; Chul Woung KIM ; Cheoul Sin KIM ; Nam Kyu SEO
Journal of Korean Academy of Oral Health 2015;39(1):56-62
OBJECTIVES: This study aimed to investigate differences in unmet dental care needs according to employment status and if factors have relevance to unmet dental care needs due to "economic burden" and "no time to spare for visiting". METHODS: Multivariate logistic regression analysis was performed to examine the factors that affected the prevalence of unmet dental care needs due to "economic burden" and "no time to spare for visiting" in an economically active population comprised of subjects aged 20-64 years. RESULTS: Compared to regular workers, part-time workers experienced 1.28-times more unmet dental care needs, while students experienced 0.64-times fewer unmet dental care needs. With regard to reasons related to "economic burden", the rate of experiencing unmet dental care needs was 1.37-times higher for part-time workers than for regular workers. Regarding reasons related to "no time to spare for visiting", the rate of experiencing unmet dental care needs was 0.51-times lower in part-time workers compared with regular workers. In economically inactive people, these values were 0.51-times lower in the unemployed, 0.37-times lower in students, 0.23-times lower in house workers, 0.20-times lower in subjects with disease and injury, and 0.20-times lower in early retirees compared to regular workers. CONCLUSIONS: Part-time workers experienced more unmet dental care needs compared with regular workers. With regard to "economic burden", a significant difference in unmet dental care needs was observed between regular workers and part-time workers. Additionally, regarding "no time to spare for visiting", people who were economically inactive because of unemployment, student or house-worker status, diseases and injury, and retirement experienced fewer unmet dental care needs compared with regular workers.
Dental Care*
;
Employment*
;
Humans
;
Logistic Models
;
Prevalence
;
Retirement
;
Unemployment
10.Epidemiological Study of Contact Dermatitis.
Hee Chul EUN ; Soo Nam KIM ; Dong Kil BYUN ; Seong Kyun IM ; Jin Tack KIM
Korean Journal of Dermatology 1982;20(2):269-279
Studies on epidemiological aspects of contact dermatitis have been published in recent years since the introduction of standardized method of patch test.However, most previous epidemiologic reports studied patients with allergic contact dermatitis in hospitals with patcb testing. Such data are not directly applicable to the population at large. Very recentiy there are a few reports ahout rates of exposure and patch test reactivity to certain antigens in a general population. which is difficult to be applicable in a developing country at present. With regard to this, we have tried to analyze the contact dermatitis questionaire containing various items of common causative agents producting contact dermatitis (for example, metals, cosmetics, plants, medicaments and rubber etc.) for the detection of past contact dermatitis histories in a total new dermatologic outpatients. A11 2258 dermatologic outpatients entered this study including 303 contact dermatitis patients (allergic contact dermatitis, primary irritant dermatitis and housewife eczema). We also analyzed the patch test results of 107 patients with suggesting contact dermatitis who visited our hospital at the same period of collecting questionaires. The study results were as follows. 1. Positive rate of each item of the questionaire (No. of said Yes/ No. of responders) was metals, 10.4% cosmetics, 31.8%, plants, 18.2%; medicaments, 12.4%; rubber, 5.8%; and others, 11.7%. 2. The most common all regens of the patch test positive reactions were nickel sulfate (9.3%), fragrance mix(9.3%), formaldehyde(6.5%), potassium dichromate (5.6%), neomycin sulfate (5.6%), balsam of Peru (4.7%), cobalt chloride(3.7%), wood tar(3.7%) and paraphenylene diamine (2.8%) in order of frequency. And the patch test positive rate of commercial cosmetic products was 10.3%. In conclusion, cosmetics, medicaments, metals, plants and rarely rubber are found the most common etiologic agents of contact dermatitis in this study. The reasons and back-ground of the results were also discussed in various aspects.
Cobalt
;
Dermatitis, Allergic Contact
;
Dermatitis, Contact*
;
Dermatitis, Irritant
;
Developing Countries
;
Epidemiologic Studies*
;
Humans
;
Metals
;
Neomycin
;
Nickel
;
Outpatients
;
Patch Tests
;
Peru
;
Potassium Dichromate
;
Rubber
;
Wood