No abstract available.
Melanoma*

Tufted hair follliculitis is a localized, inflammatory and exudative disease of the scalp characterized by a tufted appearance of the scalp hairs emerging from single follicular openings, and may result in permanent and irreversible scarring alopecia. We report two cases of tufted hair folliculitis in a 53-year-old woman and a 47-year-old man. They had several areas of scarring alopecia with multiple bundles of hairs emerging from single follicular orifices. Histopathologic findings were typical for tufted hair folliculitis. The patients were treated successively with oral antibiotics and with topical application of clindamycin.
Alopecia ; Anti-Bacterial Agents ; Cicatrix ; Clindamycin ; Female ; Folliculitis* ; Hair* ; Humans ; Middle Aged ; Scalp

No abstract available.
Blood Flow Velocity* ; Humans ; Infant, Newborn*

No abstract available.
Magnetic Resonance Imaging* ; Spinal Cord*

BACKGROUND: There are only a few studies regarding the causes of treatment failure for tuberculosis. Therefore, this study aimed to determine the causes of intractable tuberculosis. METHODS: M.tuberculosis, differentiated MOTT (Tycobacterium Other Than Tuberculosis) were isolated, and the RFLP (Restriction fragments length polymorphisms) pattern was analyzed from 204 patients with pulmonary tuberculosis and 53 suffering from neck tuberculosis. The IL-1β, IL-12, *1 IFNγ and *2 TNFαblood levels were measured. All patients were regularly followed for 18 months after treatment. RESULTS: There was no correlation between the RFLP patterns of M.tuberculosis treatment failure. From the 204 cases, 31.9% were intractable. The characteristics of patients with intractable tuberculosis were old age, being male and recurrent cases. The causes of treatment failure were identified as follows ; a decrease in the IL-12(59.4%) concentration, drug resistant strain(54.7%), irregular medication(15.4%), MOTT(6.2%) and a heavy infection(4.6%). The causes of all cases of intractable tuberculosis could be investigated. The IL-12 concentration in the blood was significantly lower in the intractable cases, where it disclosed a maximum sensitivity(64.7%) and specificity(75.4%) at 165.0 pg/ml. Most of the 53 cases on neck node tuberculosis were treated successfully. Therefore, we were unable to analyze the cause of treatment failure. CONCLUSION: A decrease in the blood IL-12 concentration and drug resistant strains were identified as the most significant causes of treatment failure for tuberculosis. In Korea, infection by clusters were prevalent, but no difference in the clinical course between clusters and non-clusters could be found.
Humans ; Interleukin-12 ; Korea ; Male ; Neck* ; Polymorphism, Restriction Fragment Length ; Treatment Failure* ; Tuberculosis* ; Tuberculosis, Pulmonary

Multiple cutaneous neurofibromas are the most common skin manifestation of Von Recklinghausen neurofibromatosis(NF-1). CO2 laser surgery is a treatment modality for multiple cutaneous neurofibromas and a simple procedure that quickly removes the tumor with minimal postoperative discomfort and acceptable cosmetic results. But, hypertrophic and atrophic scars can result from treatment with CO2 laser surgery. We herein report a case of multiple cutaneous neurofibromas that developed hypertrophic scars postoperatively.
Cicatrix ; Cicatrix, Hypertrophic* ; Lasers, Gas* ; Neurofibroma* ; Skin Manifestations

This paper describes a case of intrapericardial teratoma in a 20-day-old female meonate, who suffered from cyanosis and respiratory difficulty. She was evaluated by echocardiography, chest CT and MRI, the suspected cyanosis and respiratory difficulty. She was evaluated by echocardiography, chest CT and MRI, the suspected intrapericardial mass was identified and surgically removed. The postopervative diagnosis was intrapericardial teratoma, grade II. This case is reported with brief review of some related literature.
Cyanosis ; Diagnosis ; Echocardiography ; Female ; Humans ; Magnetic Resonance Imaging ; Teratoma* ; Tomography, X-Ray Computed

OBJECTIVE: Permanent occlusion of an aneurysm with platinum coil embolization is achieved by thrombus formation and subsequent organization of the thrombus. However, these processes are often delayed or imcomplete. In this study, the authors present the effects of autologous fibroblasts-attached platinum coils on thrombus organization. METHODS: Experimental aneurysms were made on common carotid arteries bilaterally in four dogs. During the operation, dermal fibroblasts were obtained from the neck skin. The fibroblasts were attached on platinum coils by a simple co-culture for 5 days. In each animal, one aneurysm was embolized with autologous fibroblast-attached platinum coils(study group) and the other with plain platinum coils(control group). Two weeks later, the degree of intraaneurysmal thrombus organization was compared. RESULTS: The study group aneurysms showed more advanced organization than the control group(area occupied by organized thrombus / aneurysm cross sectional area = 79% vs. 54%, p=0.02). CONCLUSION: As a pilot study, this experiment demonstrates autologous fibroblast-attached platinum coils can facilitate permanent aneurysm obliteration. Autologous fibroblast-attached platinum coils may be used for the treatment of intracranial aneurysms.
Aneurysm* ; Animals ; Carotid Artery, Common ; Coculture Techniques ; Dogs ; Embolization, Therapeutic ; Fibroblasts ; Intracranial Aneurysm ; Neck ; Pilot Projects ; Platinum* ; Skin ; Thrombosis

PURPOSE: To know the relationship between serum vitamin A level and clinical symptoms in measles patients and to re-evaluate the measles vaccination schedule, we performed this study. METHODS: From Jan. to Jun. 1994, we checked serum vitamin A levels and compared with clinical symptoms, laboratory findings, complications and vaccination status in 153 patients with positive measles IgM by ELISA. RESULTS: The results were as follows 1) The measles was most prevalent in the group of 7-9 months(26.1%) and 5-9 years(27.5%) of age. 2) Mean serum vitamin A level was 215.9+/-79.6ng/ml but it was lower than normal value(410-1200ng/ml). 3) Serum vitamin A level was significantly lower in the group of over 2 years of age (194.3+/-78.4ng/ml) than the group of under 2 years of age (230.2+/-77.8ng/ml). 4) There was no relationship between serum vitamin A level and clinical symptoms. 5) About half of the patients with measles IgM antibodies had a Measles vaccination before. The kinds of vaccination were measles vaccine only in 5.2%, MMR in 25.5% and measles and MMR both in 19.6% of 77 cases with the history of documented measles vaccination. CONCLUSIONS: Serum vitamin A level was lower than normal range in our study subjects and there was no relationship between serum vitamin A level and clinical manifestations of mealses. About half of the patients with measles in our study subjects had measles vaccination before. Therefore it is necessary to reestablish the measles vaccination schedule in children.
Antibodies ; Appointments and Schedules ; Child ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunization* ; Immunoglobulin M ; Meals ; Measles Vaccine ; Measles* ; Reference Values ; Vaccination ; Vitamin A* ; Vitamins*

Mature cystic teratoma of the ovary is the most common ovarian germ cell tumor and almost benign, but malignant transformation occurs in less than 2% of benign mature teratoma. Of the malignancies arising in teratomas, squamous cell carcinoma is the most common (70-80%). The presentation in stage I disease dose not differ from that of benign cystic teratoma. In the early stage, the treatment is possible through surgical intervention alone. We experienced a case of squamous cell carcinoma of the ovary arising in mature cystic teratoma, which is presented with a brief review of literature.
Carcinoma, Squamous Cell* ; Female ; Neoplasms, Germ Cell and Embryonal ; Ovary* ; Teratoma*