Actins ; metabolism ; Female ; Heart Atria ; pathology ; Heart Neoplasms ; secondary ; surgery ; Humans ; Iliac Vein ; pathology ; surgery ; Leiomyomatosis ; metabolism ; pathology ; surgery ; Middle Aged ; Uterine Neoplasms ; metabolism ; pathology ; surgery ; Vascular Neoplasms ; metabolism ; pathology ; surgery ; Veins ; pathology ; surgery ; Vena Cava, Inferior ; pathology

We report a case of multicentric, biatrial cardiac myxoma in a 29-year-old female who complained of exertional dyspnea, abdominal distension and peripheral edema. Any other associated skin lesions, breast mass or endocrine disorder presenting complex form were not seen on her. Also, there was no contributory medical history, hypertension and diabetes mellitus. By using transthoracic echocardiography, we identified a biatrial myxoma attached to the interatrial septum. During surgical excision, we found a large right atrial myxoma with extension through the fossa ovalis into the left atrium and small myxoma attached to the right atrial free wall. After successful resection of interatrial septum and free wall, atrial septal defect was created during the resection and safely repaired by bovine pericardial patch.
Adult ; Case Report ; Echocardiography ; Female ; Heart Neoplasms/surgery* ; Heart Neoplasms/pathology ; Heart Neoplasms/diagnosis ; Human ; Myxoma/surgery* ; Myxoma/pathology ; Myxoma/diagnosis ; Neoplasm Recurrence, Local

Heart Neoplasms ; diagnostic imaging ; secondary ; surgery ; Heart Ventricles ; pathology ; Humans ; Lung Neoplasms ; pathology ; Male ; Middle Aged ; Radiography

OBJECTIVETo review the experience and assess the value of cardiopulmonary bypass (CPB) in the treatment of locally advanced lung cancer involving the left atrium.

METHODSFrom Jan. 1999 to Dec. 2002, lobectomy or pneumonectomy combined with partial resection of the left atrium were carried out in 52 such patients, which included 13 with assistance of CPB and 39 without.

RESULTSThere was one postoperative death in each of the CPB and non-CPB groups due to brbonchopleural fistula and pulmonary infection. Six patients in CPB and 14 in non-CPB groups developed postoperative cardiac complication including arrhythmia, pneumonia and heart failure. The 1-, 3-year survival rate of CPB and non-CPB groups was 69.3%, 66.7% and 38.5%, 38.5%, respectively.

CONCLUSIONCombined resection of locally advanced lung cancer with partially involved left atrium through cardiopulmonary bypass was safe and effective, and may not increase the postoperative complication and risk.

Adenocarcinoma ; pathology ; surgery ; Adult ; Carcinoma, Squamous Cell ; pathology ; surgery ; Cardiopulmonary Bypass ; Female ; Follow-Up Studies ; Heart Atria ; pathology ; surgery ; Heart Neoplasms ; pathology ; surgery ; Humans ; Lung Neoplasms ; pathology ; surgery ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Staging ; Pneumonectomy ; adverse effects ; Survival Analysis

Pathologic diagnosis of a cardiac mass is vital in determining the proper treatment modality. Open heart surgery or transesophageal echocardiography guided biopsy can be feasible methods to confirm the pathology. However, the former is highly invasive and both methods require general anesthesia. The introduction of intracardiac echocardiography (ICE) can provide good anatomic information of heart and does not require general anesthesia. In this report, we present two cases of cardiac tumors which were confirmed by percutaneous biopsy under the guidance of an ICE. The patients underwent cardiac biopsy without any complications.
Anesthesia, General ; Biopsy* ; Diagnosis ; Echocardiography* ; Echocardiography, Transesophageal ; Heart ; Heart Neoplasms ; Humans ; Ice ; Pathology ; Thoracic Surgery

Adult ; Female ; Follow-Up Studies ; Heart Neoplasms ; secondary ; surgery ; Humans ; Leiomyoma ; pathology ; surgery ; Leiomyomatosis ; surgery ; Pelvic Neoplasms ; secretion ; surgery ; Pulmonary Artery ; pathology ; Reoperation ; Uterine Neoplasms ; pathology ; surgery ; Vascular Neoplasms ; secretion ; surgery ; Vena Cava, Inferior ; pathology

OBJECTIVETo investigate clinical characteristics and rational surgical therapy for cardiac cancer patients over 70 years.

METHODSFrom 1991 to 2003, clinical data of 206 patients with advanced cardiac cancer were collected and analyzed. The patients were divided into two groups as the group of patients over 70 years old (103 cases) and the group younger than 70 years old (100 cases).

RESULTSThere were no significant differences in tumor pathologic types, tumor staging and surgical approaches(P> 0.05),but there were significant differences in clinical symptoms and coexistent diseases between two groups(P< 0.01). Patients over 70 years had main clinical symptom of dysphagia in 64% ,coexistent heart and lung disease in 63% and 73% ,respectively; anaemia and hypoproteinemia in 63% and 34% ,respectively. Total gastrectomy via abdomen was performed in 78% and 73% of two groups respectively (P> 0.05). There was no significant difference in postoperative complications such as pulmonary infection between the two groups. The operative mortality was 3% and 2% in two groups respectively (P> 0.05).

CONCLUSIONTotal gastrectomy via abdomen is a safe approach for advanced cardiac cancer patients older than 70 years. The function of vital organs should be examined before operation. It is important to take certain measurements to prevent patients from postoperative complications.

Aged ; Aged, 80 and over ; Female ; Gastrectomy ; Heart Neoplasms ; pathology ; surgery ; Humans ; Male ; Neoplasm Staging ; Prognosis ; Stomach Neoplasms ; pathology ; surgery

Primary cardiac sarcomas are extremely rare. We report a case of a primary cardiac sarcoma with myxoid change, which originally presented as a benign cardiac myxoma on a two- dimensional echocardiogram. On operating, the mass was found to extend into the posterior left atrial wall, the left pulmonary vein, and the mitral valve. The patient underwent wide resection of the left atrium, a mitral valve replacement and a left pneumonectomy. The histological diagnosis was of an undifferentiated primary cardiac sarcoma. The patient had postoperative chemotherapy. The patient expired 11 months after surgery due to a recurrence of the cardiac sarcoma. Although most tumors that develop in the left atrium are benign myxomas, we should make a preoperative differential diagnosis.
Adult ; Diagnosis, Differential ; Female ; Heart Atria ; Heart Neoplasms/*pathology/surgery/ultrasonography ; Human ; Intraoperative Period ; Myxoma/*pathology/ultrasonography ; Sarcoma/*pathology/surgery/ultrasonography

OBJECTIVETo study the disease spectrum, clinical and pathologic features of primary cardiac neoplasms at a single medical institution during a period of eight years.

METHODSThe clinical and pathologic features of 81 cases of primary cardiac neoplasms encountered at the Affiliated Hospital of Medical College, Qingdao University from January, 2004 to December, 2011, either for cardiovascular surgery or as pathology consultation cases, were retrospectively reviewed. Immunohistochemical study was carried out in selected examples.

RESULTSAmongst the 81 cases studied, 73 cases (90.1%) were benign and 8 cases (9.9%) were malignant. Cardiac myxomas accounted for 97.3% (71/73) of all the benign cases. Six of the 8 malignant cases represented soft tissue sarcomas. The commonest presenting symptom was dyspnea. The histologic subtypes included myxoma (number = 71), angiosarcoma (number = 2), malignant fibrous histiocytoma (number = 2), hemangioma (number = 1), liposarcoma (number = 1), lymphoma (number = 1), myxofibrosarcoma (number = 1) and papillary fibroelastoma (number = 1).

CONCLUSIONSWhile the majority of primary cardiac neoplasms are myxomas, other tumor types do exist. Accurate histologic diagnosis and timely surgery are crucial in patient management.

Adolescent ; Adult ; Aged ; Child ; Female ; Fibroma ; metabolism ; pathology ; surgery ; Fibrosarcoma ; metabolism ; pathology ; surgery ; Follow-Up Studies ; Heart Neoplasms ; metabolism ; pathology ; surgery ; Hemangioma ; metabolism ; pathology ; surgery ; Hemangiosarcoma ; metabolism ; pathology ; surgery ; Histiocytoma, Malignant Fibrous ; metabolism ; pathology ; surgery ; Humans ; Immunohistochemistry ; Liposarcoma ; metabolism ; pathology ; surgery ; Lymphoma ; metabolism ; pathology ; surgery ; Male ; Middle Aged ; Myxoma ; metabolism ; pathology ; surgery ; Sarcoma ; metabolism ; pathology ; surgery ; Treatment Outcome ; Vimentin ; metabolism ; Young Adult

Adult ; Anticoagulants ; therapeutic use ; Carcinoma, Renal Cell ; complications ; pathology ; surgery ; Echocardiography ; Female ; Heart Atria ; diagnostic imaging ; pathology ; Humans ; Kidney Neoplasms ; complications ; pathology ; surgery ; Leiomyomatosis ; complications ; pathology ; surgery ; Thromboembolism ; diagnostic imaging ; drug therapy ; etiology ; Treatment Outcome ; Uterine Neoplasms ; complications ; pathology ; surgery