To present a case of a patient who will undergo pulmonary embolectomy under deep hypothermic circulatory arrest, to discuss the use of deep hypothermic circulatory arrest, and to elaborate on the various techniques utilized to provide optimum neuroprotection.
Human ; Female ; Middle Aged ; HYPOTHERMIA ; NEUROPROTECTIVE AGENTS ; CIRCULATORY ARREST, DEEP HYPOTHERMIA INDUCED ; HEART ARREST, INDUCED

Advances in anesthetic and surgical management, such as deep hypothermic circulatory arrest and temporary clipping, have improved outcomes for intracranial aneurysm patients. However, these techniques are associated with significant risks. We report on two cases in which adenosine administration was used to induce transient periods of cardiac asystole during intracranial aneurysm surgery. This asystole resulted in profound hypotension and collapse of the aneurysm, which facilitated its safe clipping.
Adenosine ; Aneurysm ; Circulatory Arrest, Deep Hypothermia Induced ; Heart Arrest ; Humans ; Hypotension ; Intracranial Aneurysm

Reoperation on the recurrent aortic aneurysm adjuvent to sternum remains a challenging problem in regard to the risk of the massive hemorrhage at the time of resternotomy resulting from inadvertent entry into the aneurysmal sac. The cardiopulmonary bypass technique of femoral cannulation and deep hypothermic circulatory arrest can provide a safe resternotomy. The left ventricle is likely to distend due to lack of contraction with ventricular fibrillation during core cooling. To prevent ventricular distention during core cooling, sufficient venous drainage is mandatory. We report a technique in which deep hypothermic circulatory arrest is achieved before resternotomy without left ventricular distention by active venous drainage using centrifugal pump.
Aneurysm ; Aortic Aneurysm* ; Cardiopulmonary Bypass ; Catheterization ; Circulatory Arrest, Deep Hypothermia Induced* ; Drainage ; Heart Ventricles ; Hemorrhage ; Hypothermia ; Hypothermia, Induced ; Reoperation ; Sternum* ; Ventricular Fibrillation

Renal cell carcinoma is associated with inferior vena cava tumor spread in 4~10% of cases and with extension of the tumor thrombus into the right atrium in less than 1% of cases. Because inferior vena caval involvement does not affect the ultimate survival in patients with nonmetastatic renal cell carcinoma, aggressive surgical resection is indicated. We experienced a case of complete tumor excision with radical nephrectomy and inferior vena caval and right atrial thrombectomy using adjunctive cardiopulmonary bypass(CPB) and deep hypothermic circulatory arrest(DHCA). During total circulatory arrest(TCA), we protected brain from ischemic insult using deep hypothermia, retrograde cerebral perfusion, thiopental, and high dose steroid. The patient recovered uneventfully except minor neuropsychiatric symptom for 3 weeks after operation.
Brain ; Carcinoma, Renal Cell* ; Circulatory Arrest, Deep Hypothermia Induced* ; Heart Atria* ; Humans ; Hypothermia ; Nephrectomy ; Perfusion ; Thiopental ; Thrombectomy ; Thrombosis ; Vena Cava, Inferior

We present a case of a patient who had undergone human allograft cardiac transplantation 5 months before ascending aorta replacement. A pseudoaneurysm at the anastomotic site of ascending aorta with periaortic hematoma compressing the superior vena cava (SVC) had been revealed by chest CT, and after the median sternotomy, paraaortic abscess was revealed as the cause of this patient's SVC syndrome. The ascending aorta replacement was performed under deep hypothermic circulatory arrest. The anesthetic management of this patient included the use of a sterile technique, slow cautious induction, and the maintenance of adequate intravascular volume.
Abscess ; Allografts ; Aneurysm, False ; Aorta* ; Circulatory Arrest, Deep Hypothermia Induced* ; Heart Transplantation ; Heart* ; Hematoma ; Humans ; Sternotomy ; Tomography, X-Ray Computed ; Vena Cava, Superior

BACKGROUND: The thoracic and thoracoabdominal aortic surgery is a complicated procedure that has various method of approach and protection. The authors have performed several methods to treat these diseases. Therefore, we attempt to analyze their results and risks. MATERIAL AND METHOD: From June of 1992 to August of 2001, we performed 26 cases of thoracic aortic surgery and 10 cases of thoracoabdominal aortic surgery. There were 17 aortic dissections, 17 aortic aneurysms, one coarctation of aorta and one traumatic aortic aneurysm. The thoracic aortic replacement was performed under a femorofemoral bypass, an LA to femoral bypass, or a deep hypothermic circulatory arrest. The thoracoabdominal aortic replacement was performed under a femorofemoral bypass or a pump assisted rapid infusion. RESULT: There were 7 renal failures, 11 hepatopathies, 7 cerebral vascular accidents, 2 heart failures, 5 respiratory insufficiencies, and 2 sepsis in postoperative period. There were 9 hospital mortalities which were from 2 bleedings, 2 heart failures, 2 renal failures, a sepsis, a respiratory failure, and a cerebral infarction. There were 3 late deaths which were from ruptured distal anastomosis, cerebral infarction, and pneumonia. CONCLUSION: Deep hypothermic circulatory arrest was not good supportive methods for thoracic aortic replacement. Total thoracoabdominal aortic replacement was a high risk operation.
Aorta, Thoracic ; Aortic Aneurysm ; Aortic Aneurysm, Thoracic ; Aortic Coarctation ; Cerebral Infarction ; Circulatory Arrest, Deep Hypothermia Induced ; Heart ; Hospital Mortality ; Pneumonia ; Postoperative Period ; Renal Insufficiency ; Respiratory Insufficiency ; Sepsis

BACKGROUND: Diagnosing chronic pulmonary embolism at an early stage is difficult because of the patient's non-specific symptoms. This condition is not prevalent in Korea, and in fact, there have been only a few case reports on this in the Korean medical literature. We analyzed the surgical outcome of performing pulmonary thromboendarterectomy in patients with chronic pulmonary embolism. MATERIAL AND METHOD: The study subjects included those patients who underwent surgery for chronic pulmonary embolism from 1996 to 2008. For making the diagnosis, echocardiography, chest CT and a pulmonary perfusion scan were performed on the patients who complained of chronic dyspnea. RESULT: Pulmonary endarterectomy was performed as follows: by incision via a mid-sternal approach (7 patients); by incision via a left posterolateral approach (1 patient); using the deep hypothermic circulatory arrest technique (4 patients); under ventricular fibrillation (3 patients); and under cardioplegic arrest (1 patient). The postoperative systolic pulmonary artery blood pressure significantly decreased from a preoperative value of 78.9+/-14.5 mmHg to 45.6+/-17.6 mmHg postoperatively (p=0.000). The degree of tricuspid regurgitation was less than grade II after surgery. Two patients died early on, including one patient who had persistent pulmonary hypertension without improvement and right heart failure. CONCLUSION: Patients who have chronic pulmonary embolism are known to have a poor prognosis. However, we think that early surgical treatment along with making the proper diagnosis before the aggravation of right heart failure can help improve the quality of a patient's life.
Blood Pressure ; Circulatory Arrest, Deep Hypothermia Induced ; Dyspnea ; Echocardiography ; Endarterectomy ; Heart Failure ; Humans ; Hypertension, Pulmonary ; Korea ; Perfusion ; Prognosis ; Pulmonary Artery ; Pulmonary Embolism ; Thorax ; Tricuspid Valve Insufficiency ; Ventricular Fibrillation

BACKGROUND: Deep hypothermic circulatory arrest during repair of aortic arch anomalies may induce neurological complications or myocardial injury. So we surveyed if the regional cerebral and myocardial perfusion might eliminate those potential side effects. MATERIAL AND METHOD: From March 2000 to December 2004, 62 neonates or infants with aortic arch anomaly underwent one stage biventricular repair using the regional perfusion technique by single surgeon. Preoperative diagnosis of the arch anomaly consisted of coarctation (n=46), interruption of the aorta (n=12), hypoplastic left heart syndrome (n=2) and truncus areteriosus (n=2). Combined anomalies were ventricular septal defect (n=51), TAPVR (n=1), PAPVR (n=1) and atrioventricular septal defect (n=2). Arterial cannula was inserted at the innominate artery. RESULT: The mean regional perfusion time of brain was 28+/-10 min. Operative mortality rates was 0 (0/62). Late death was 1 (1/62) during 11+/-7 months of follow-up. Neurologic complications consisted of transient chorea in 1 case. There was no reoperation associated with arch anolamy. Pulmonary complication associated with arch repair occurred in 1 case which was managed by aortopexy. CONCLUSION: One-stage arch repair using the regional prefusion is safe and effective in minimizing the neurologic and myocardial complications.
Aorta ; Aorta, Thoracic* ; Brachiocephalic Trunk ; Brain ; Catheters ; Chorea ; Circulatory Arrest, Deep Hypothermia Induced ; Diagnosis ; Follow-Up Studies ; Heart Septal Defects, Ventricular ; Humans ; Hypoplastic Left Heart Syndrome ; Hypothermia ; Infant ; Infant, Newborn ; Mortality ; Perfusion* ; Regional Blood Flow ; Reoperation ; Scimitar Syndrome

OBJECTIVETo discuss the experience of surgical treatment of total anomalous pulmonary venous connection (TAPVC) in infants.

METHODSThe clinic data of 84 cases with TAPVC under 6 months of age underwent surgical treatment at Department of Cardiac Surgery, Guangzhou Women and Children's Medical Center from January 2012 to October 2015 were analyzed retrospectively. There were 58 male and 26 female patients. The patients were aged 1 days to 6 months with a mean of (2.4±2.2) months at surgery, including 22 newborns. Body weight was 1.8 to 6.8 kg with a mean of (4.3±1.2) kg. There were 24 cases of intracardiac type, 46 cases of supracardiac type, 10 cases of infracardiac type and 4 cases of mixed type. There were 26 cases received emergent operation. There were 14 cases used Sutureless technique in operations and 46 cases used conventional methods in the no-intracardiac type cases, and 2 cases enlarged the anastomsis with autologous pericardium. According to the condition, corrective surgeries of other anomalies were performed in the meantime, including 3 Warden operations (right side), 3 bilateral bidirectional Gleen operation, 2 correction of unroofed coronary sinus syndrome, 1 coarctation of aorta correction with deep hypothermic circulation arrest, and 1 repair of ventricular septal defect.

RESULTSThe ratio of newborn was higher in Sutureless technique group than in conventional methods group (7/14 vs. 32.6%, χ(2)=4.927, P=0.043), and mean age was less ((1.8±0.4) months vs. (2.4±2.2) months, F=4.257, P=0.042), but there were no difference in body weight, cardiopulmonary bypass time and aorta clamped time between the two groups. Followed up for 1 to 46 months, 10 cases (11.9%) died overall and the mortality of intracardiac (3/10) and mixed (2/4) type were much higher than in intracardiac (4.2%) and supracardiac (13.0%) type. The mortality were no difference between newborn and infants, or whether emergent operation, or Sutureless technique and conventional methods. The maximal pulmonary venous flow velocity was abnormal speed-up >1.8 m/s at 1 week and 1 to 3 months post-operation mostly.

CONCLUSIONSThe mortality of TAPVC was differed by different types. Intrinsic pulmonary vein stenosis maybe the main cause of mortality. The high quality of anastomsis could reduce the operative mortality.

Aortic Coarctation ; Body Weight ; Cardiac Surgical Procedures ; methods ; Circulatory Arrest, Deep Hypothermia Induced ; Female ; Heart Defects, Congenital ; mortality ; surgery ; Heart Septal Defects, Ventricular ; Humans ; Infant ; Infant, Newborn ; Male ; Postoperative Period ; Pulmonary Veins ; pathology ; surgery ; Retrospective Studies

There has been an improvement in the prognosis of the tumor thrombi invading the inferior vena cava (IVC) and the right atrium (RA) of the renal cell carcinoma with radical nephrectomy and tumor thrombectomy with the aid of a cardiopulmonary bypass. A 26 year old man was diagnosed with the right renal tumor with a tumor invading the right renal vein and the IVC above the right renal vein to the RA and right venticle. He was presented with dyspnea on the exertion, the ascites and the lower extremity edema due to IVC total obstruction. An acute hepatic failure occurred due to an obstruction of the hepatic vein. She received a radical nephrectomy and a removal of the tumor in the IVC and the right cardiac camber under a hypothermic total circulatory arrest using the cardiopulmonary bypass.
Ascites ; Carcinoma, Renal Cell ; Cardiopulmonary Bypass ; Circulatory Arrest, Deep Hypothermia Induced* ; Dyspnea ; Edema ; Heart Atria ; Heart Ventricles* ; Hepatic Veins ; Kidney Neoplasms ; Liver Failure, Acute ; Lower Extremity ; Nephrectomy ; Prognosis ; Renal Veins ; Sarcoma* ; Thrombectomy ; Vena Cava, Inferior*