Hearing Loss, Sudden ; Humans

OBJECTIVES: Although many studies have assessed sudden deafness in adults, sudden deafness has not been evaluated in children. We therefore evaluated the differences in sudden deafness between children and adults. METHODS: We compared clinical manifestations, including gender, audiogram pattern of initial hearing loss, and recovery rate after treatment in 87 children and 707 adults diagnosed with sudden deafness from September 2003 and August 2012. RESULTS: There were no differences in sex, side, or audiogram between children and adults (P>0.05 each). Hearing recovery rates in children and adults were 72.4% and 70.6%, respectively (P>0.05). Both children and adults with mild hearing loss showed significantly greater hearing recovery rates than individuals with profound hearing loss (P<0.05 each). The percentage with initially mild and moderate hearing loss was higher in children than in adults, as were the recovery rates of children compared to adults with initially mild, moderate-severe, and profound hearing loss (P<0.05 each). In regard to final hearing outcome after treatment, a low percentage of children showed no improvement whereas a high percentage showed complete recovery; a higher percentage of children than of adults showed complete recovery (P<0.05). Recovery rate from profound hearing loss was significantly higher in children than in adults (60.0% vs. 45.4%, P<0.05). CONCLUSION: Degree of hearing loss, gender, side, and recovery rate were similar in children and adults, but the rate of complete recovery was higher in children.
Adult* ; Child* ; Hearing ; Hearing Loss ; Hearing Loss, Sudden* ; Humans

BACKGROUND AND OBJECTIVES: Zinc has antioxidant effect, anti-inflammatory effect and neuromodulative function. The purpose of this study was to investigate whether treatment with zinc can improve the outcome of sudden sensorineural hearing loss (SSNHL). SUBJECTS AND METHOD: The study group consisted of 143 patients diagnosed as SSNHL. Of the patients, 82 were given corticosteroid treatment (group Ct) and 61 were given oral zinc plus corticosteroid treatment (group Zn). In group Zn, serum zinc level was checked before treatment and the patients with normal serum zinc level were included. Hearing was assessed before therapy and at 2 weeks, 1 month and 2 months after the initiation of therapy. RESULTS: A significantly larger hearing gain in pure tone average (group Ct vs. group Zn=26.40 dB HL vs. 34.28 dB HL) and at 2000 Hz (group Ct vs. group Zn=24.93 dB HL vs. 33.60 dB HL) and 8000 Hz (group Ct vs. group Zn=11.64 dB HL vs. 20.66 dB HL) were seen in group Zn compared with the group Ct. CONCLUSION: Oral zinc supplementation may have beneficial effects in the treatment of SSNHL, especially at 2000 and 8000 Hz.
Antioxidants ; Hearing ; Hearing Loss, Sensorineural* ; Hearing Loss, Sudden ; Humans ; Zinc*

No abstract available.
Arteries* ; Hearing Loss, Sudden* ; Hearing Loss, Unilateral ; Infarction* ; Pons

Humans ; Consensus ; Hearing Loss, Sensorineural/therapy* ; Hearing Loss, Sudden/therapy*

Autophagy ; Hearing Loss, Sensorineural ; Hearing Loss, Sudden ; Humans

While systemic steroid therapy is most widely considered as a main treatment for idiopathic sudden sensorineural hearing loss (SSHL), the disadvantages of its use are numerous side effects. Intratympanic steroid injection (ITS) delivers steroids through transtympanic route, hence avoids possible side effects with higher perilymph concentration. We conducted a reviewed 47 clinical studies after an online search of the PubMed databases for the following terms "sudden hearing loss, intratympanic steroid". Although the study settings are varied among reviewed articles, most studies in this review consistently showed some benefit of hearing in salvage cases. In addition, it is suggested that intratympanic steroids are equivalent to systemic steroid therapy as initial treatment for SSHL. In patients with contraindications against the use of systemic steroid, ITS may be considered as valuable option for primary therapy. Further studies are necessary to elucidate the optimal protocol of administration.
Hearing ; Hearing Loss ; Hearing Loss, Sensorineural ; Hearing Loss, Sudden ; Humans ; Perilymph ; Steroids

While systemic steroid therapy is most widely considered as a main treatment for idiopathic sudden sensorineural hearing loss (SSHL), the disadvantages of its use are numerous side effects. Intratympanic steroid injection (ITS) delivers steroids through transtympanic route, hence avoids possible side effects with higher perilymph concentration. We conducted a reviewed 47 clinical studies after an online search of the PubMed databases for the following terms "sudden hearing loss, intratympanic steroid". Although the study settings are varied among reviewed articles, most studies in this review consistently showed some benefit of hearing in salvage cases. In addition, it is suggested that intratympanic steroids are equivalent to systemic steroid therapy as initial treatment for SSHL. In patients with contraindications against the use of systemic steroid, ITS may be considered as valuable option for primary therapy. Further studies are necessary to elucidate the optimal protocol of administration.
Hearing ; Hearing Loss ; Hearing Loss, Sensorineural ; Hearing Loss, Sudden ; Humans ; Perilymph ; Steroids

Salicylate, the active ingredient of aspirin can cause sensorineural hearing loss and tinnitus when plasma concentrations reach a critical level. The ototoxic mechanisms of salicylate remain unclear but hearing and tinnitus usually recovers a few days after intoxication. There have been few reports of salicylate-induced ototoxicity in Korea, and the majority is caused by a low dose of aspirin. Herein, we report a case of sudden hearing loss and tinnitus after acute salicylate intoxication and review recent updates on salicylate ototoxicity.
Aspirin ; Hearing ; Hearing Loss ; Hearing Loss, Sensorineural ; Hearing Loss, Sudden ; Korea ; Plasma ; Sodium Salicylate ; Tinnitus

BACKGROUND AND OBJECTIVES: Presence of whirling vertigo accompanied by sudden sensorineural hearing loss has been known to give negative effects on the hearing recovery. But the effect of whirling vertigo on the recovery of hearing cannot be simply evaluated because prognosis is related with other several variables, such as severity of hearing loss, onset of treatment and age. This study sets out to investigate the impact of whirling vertigo on the severity and recovery of hearing loss by multivariant analysis to exclude the effects of other variables. MATERIALS AND METHOD: A total of 176 patients who were admitted to Samsung Medical Center from March 1997 to March 2001 were entered into our study. All patients were divided into three groups according to the presence of dizziness: with whirling vertigo (39 ears), with non-whirling dizziness (36 ears), without dizziness (101 ears). To investigate the impact of whirling vertigo on the severity of hearing loss, each group was divided into four groups according to the severity of hearing loss. Each group was analyzed respectively by the presence of whirling vertigo. Secondly, the effect of whirling vertigo on hearing recovery was investigated by multivariant analytic technique to exclude the effect of the other probable prognostic factors. Thirdly, the effect of other variables (severity of hearing loss, onset of treatment, age) on the prognosis was investigated. RESULTS: The presence of whirling vertigo was not statistically related with the severity of hearing loss (p=0.063). The results of the multivariant analysis showed that the recovery of hearing loss was related with the presence of whirling vertigo (p=0.02), severity of hearing loss (p=0.001), onset of treatment (p=0.034) and age (p=0.034). CONCLUSION: Hearing loss in the group with whirling vertigo was not more severe than that in the other two groups. According to the multivariant analytic technique, whirling vertigo in sudden sensorineural hearing loss has a negative effect on the prognosis of hearing recovery.
Dizziness ; Hearing ; Hearing Loss ; Hearing Loss, Sensorineural* ; Hearing Loss, Sudden ; Humans ; Prognosis ; Vertigo*