1.3D-FLAIR MRI findings in idiopathic sudden sensorineural hearing loss and the correlations with clinical features and prognosis.
Ming Ming WANG ; Ying Jun WANG ; Na HU ; Qing An XU ; Xiao SUN ; Zhi Qiang HOU ; Zhao Min FAN ; Hai Bo WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2021;56(5):424-430
Objective: To explore the correlations of different appearances of labyrinthine 3D-FLAIR MRI with clinical features and prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Methods: Clinical data of patients with unilateral ISSNHL hospitalized from May 2017 to January 2019 were retrospectively analyzed. According to the results of 3D-FLAIR MRI, the patients were divided into three groups including hyperintense with absorption, hyperintense without absorption and normal. The differences and correlations among the three groups in clinical characteristics (gender, age, deafness side, duration, treatment days, dizziness/vertigo, basic diseases, vestibular function, deafness classification and typing) and prognosis were analyzed by SPSS 20.0 software. Results: Data were collected from 1 245 cases, including 739 (59.36%) with normal signal, 288 (23.13%) hyperintense without absorption, and 218 (17.51%) hyperintense with absorption. The side ratio, treatment days, dizziness/vertigo incidence, vestibular dysfunction, deafness classification and typing were different among the three groups (P<0.001). The incidence of right side was significantly higher in both the hyperintense with and without absorption groups than that in the normal. The vestibular dysfunction was more common in the hyperintense with absorption group than in the normal and hyperintense without absorption groups. It showed statistical differences in the dizziness/vertigo incidence, deafness classification, treatment days, and deafness typing compared between groups, which was the most significant in the hyperintense with absorption group, followed by the hyperintense without absorption group. There was no statistical difference in the total effective rate among the three groups (P=0.139), whereas a significant difference in the recovery rate (P<0.001). The prognosis was significantly correlated with duration, age, treatment days and dizziness/vertigo in the normal group (all P<0.001), correlated with duration and treatment days in the hyperintense with absorption group (both P<0.001), only correlated with the duration in the hyperintense without absorption group (P<0.001). Conclusion: 3D-FLAIR MRI manifestation is closely related to the clinical features and efficacy of ISSNHL. It is helpful to clarify the pathology of inner ear, which is expected to be a new imaging indicator for disease evaluation.
Hearing Loss, Sensorineural/diagnostic imaging*
;
Hearing Loss, Sudden/diagnostic imaging*
;
Humans
;
Magnetic Resonance Imaging
;
Prognosis
;
Retrospective Studies
2.CT and MRI study in severe sensorineural hearing loss in children.
Zhongfang XIA ; Zhinan WANG ; Jianbo SHAO ; Zhongqiang XU ; Enming XU ; Yan ZHANG ; Yanjun TU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(13):601-602
OBJECTIVE:
To investigate the value of CT and MRI in diagnosing the children with sensorineural hearing loss.
METHOD:
Ninety-six cases suspected as severe sensorineural hearing loss were examined by CT/MRI system and 3D reconstruction.
RESULT:
Of 96 cases, 15 cases were found malformation these malformation included Michel, cochlear hypoplasia, commun cavity, Mondini, inner canal straitness, cochlear nerve undeveloped and vestibular aqueduct enlargements.
CONCLUSION
There are 15.63% inner ear malformation occurred in sensorineural hearing loss children. CT and MRI of inner ear have a great clinical value in diagnosing children sensorineural hearing loss by learning the anatomy.
Child
;
Child, Preschool
;
Hearing Loss, Sensorineural
;
diagnosis
;
diagnostic imaging
;
Humans
;
Infant
;
Magnetic Resonance Imaging
;
Tomography, X-Ray Computed
3.The progress of inner ear malformation in radiological research.
Dehua KONG ; Kuang FU ; Hui ZHAO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2016;30(1):88-90
Inner ear malformations are anomalies linking to development insults at different periods of embryogenesis,which are common causes of congenital sensorineural hearing loss. The evaluation of pediatric sensorineural hearing loss mostly depends on high-resolution computed tomography and magnetic resonance imaging, which can excellently depict the temporal bones and inner ear malformations.
Ear, Inner
;
abnormalities
;
diagnostic imaging
;
embryology
;
Hearing Loss, Sensorineural
;
congenital
;
Humans
;
Magnetic Resonance Imaging
;
Temporal Bone
;
abnormalities
;
diagnostic imaging
;
Tomography, X-Ray Computed
4.Observation of foramina hypoplasia within internal auditory canal fundus with CT virtual endoscopy.
Shanshan SUN ; Wuxian GONG ; Ruozhen GONG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2007;21(22):1011-1014
OBJECTIVE:
To observe normal and abnormal findings of foramina within internal auditory canal (IAC) fundus with Virtual Endoscopy of multisection helical Computed Tomography.
METHOD:
CT scanning of temporal bone was undergone in 25 volunteers (50 ears) in the normal group, in 8 cases (13 ears) with foramina hypoplasia within IAC fundus which were shown on CT and MRI images. CT virtual endoscopy (CTVE) findings were observed in the normal and abnormal groups. The lower threshold value was 900-1200 HU, the upper value was 3,071 HU in CTVE definitions.
RESULT:
The shape and position of foramina within IAC fundus were shown on the CTVE image, 50 foramina within IAC fundus were shown in all normal cases. In abnormal group, 9 ears were shown as IAC fundus disorder and foramina absent, only 1 foramina was shown in 1 ear, 2 foramen in 4 ears, 3 foramen in 2 ears, 4 foramen in 2 ears; Abnormal shape of cochlear nerve foramina was seen in 4 ears. Other malformations were also shown, including IAC malformations in 3 ears and inner ear malformations in 8 ears.
CONCLUSION
CTVE is useful to show the shape and position of normal foramina and pathological changes in the patients with foramina hypoplasia within IAC fundus.
Adolescent
;
Adult
;
Case-Control Studies
;
Child
;
Child, Preschool
;
Cochlear Nerve
;
abnormalities
;
diagnostic imaging
;
Ear Canal
;
abnormalities
;
diagnostic imaging
;
Ear, Inner
;
abnormalities
;
diagnostic imaging
;
Female
;
Hearing Loss, Sensorineural
;
congenital
;
diagnostic imaging
;
Humans
;
Male
;
Middle Aged
;
Tomography, Spiral Computed
;
methods
;
Young Adult
5.The imaging characteristics and prognosis of patients with cochlear implants whose cochlear nerves are not shown on MRI.
Jian Fen LUO ; Xiu Hua CHAO ; Rui Jie WANG ; Xue Ming LIU ; Qing An XU ; Zhao Min FAN ; Lei XU ; Hai Bo WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2021;56(12):1283-1291
Objective: To analyze the temporal bone CT and inner ear magnetic resonance imaging characteristics of cochlear implant patients with no cochlear nerve display in the inner auditory canal under MRI. To retrospectively analyze the long-term hearing and speech rehabilitation effects of such patients after cochlear implant. And to analyze the correlation between the results of imaging examinations and the postoperative effects of cochlear implant patients with this type of cochlear nerve deficiency. Methods: A total of 88 children with cochlear nerve deficiency, who underwent cochlear implantation in Shandong Provincial ENT Hospital from May 2014 to October 2018, were enrolled. Patients with cochlear malformations were excluded,only the patients with cochlear nerve deficiency whose cochlear structure was normal and no cochlear nerve displayed in inner auditory canal under MRI were enrolled. There were 64 patients, including 4 bilaterally implanted, 68 ears in total, with an average age of (2.8±1.7) years (range 1-6 years) at the time of implantation. The implanted product was Cochlear, including 24RECA and 512 models. All patients underwent inner ear magnetic resonance imaging and temporal bone CT scan before operation. Auditory speech function assessments were performed at 12 months, 24 months, and 36 months after surgery, including categories of auditory performance (CAP), speech intelligibility rating (SIR) and hearing aid threshold test. The imaging evaluation content included the width of the cochlear nerve canal of temporal bone CT, the width of the internal auditory canal, the width of the auditory nerve at the cerebellopontine angle of the inner ear MRI, and the ratio of the facial nerve to the width of the auditory nerve at the cerebellopontine angle. The correlations between the results of postoperative hearing aid hearing threshold, CAP, SIR and imaging results were analyzed. Results: Among the 64 cases of cochlear nerve not shown under MRI, 56 ears with CT data showed that the width of the cochlear nerve canal in temporal bone CT was (0.72±0.30) mm (mean±standard deviation, the same below), and the width of the internal auditory canal was (4.07±1.10) mm; 66 ears with MRI data showed that the diameter of the auditory nerve at the cerebellopontine angle of the inner ear MRI was (1.58±0.27) mm, the diameter of the facial nerve was (1.57±0.27) mm, and the ratio of the diameter of the facial nerve to the auditory nerve was (1.02±0.23). The average hearing thresholds at 12, 24, and 36 months after surgery were (46.8±2.5) dB HL, (40.7±0.8) dB HL, and (36.8±1.5) dB HL, respectively. The preoperative and postoperative CAP scores at 12, 24 and 36 months were (1.0±1.0), (3.8±1.4), (4.5±1.4) and (5.1±0.7) points, respectively. The preoperative and postoperative SIR scores at 12, 24, and 36 months were (1.1±0.3), (1.9±0.9), (2.5±0.9), and (2.9±0.6) points, respectively. The hearing threshold at 24 months after surgery was negatively correlated with the width of the internal auditory canal of temporal bone CT (r=-0.349, P=0.037), and the hearing threshold at 36 months after surgery was positively correlated with the ratio of the diameter of the facial nerve to the auditory nerve at the cerebellopontine angle of the inner ear MRI (r=0.740, P=0.001). Conclusions: Children with cochlear implants whose cochlear nerves are not shown on MRI can benefit from cochlear implantation, and their speech and auditory functions can improve significantly after surgery. The width of the internal auditory canal in the temporal bone CT and the ratio of the diameter of the facial nerve to the auditory nerve at the cerebellopontine angle of the inner ear MRI may be related to the long-term hearing threshold after surgery.
Child
;
Child, Preschool
;
Cochlear Implantation
;
Cochlear Implants
;
Cochlear Nerve/diagnostic imaging*
;
Hearing Loss, Sensorineural/surgery*
;
Humans
;
Infant
;
Magnetic Resonance Imaging
;
Prognosis
;
Retrospective Studies
;
Speech Intelligibility
6.Clinic significance of CT scan in diagnosis and management unsudden unilateral sensorineural hearing loss.
Ping GUO ; Tongli REN ; Wuqing WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(10):685-687
OBJECTIVE:
To investigate the clinic significance of the temporal bone high-resolution CT in discovering unilateral sensorineural hearing loss of adolescents, and to provide the basis for the rational using of medical resources.
METHOD:
A retrospective study was conducted on 28 outpatients with unilateral sensorineural hearing loss at unsure time. Their medical history and CT examine were reevaluated,combined with associated articles in this report.
RESULT:
All of the 28 patients with unilateral sensorineural hearing loss had the normal external ear and middle ear and received CT scan. Nine out of twenty-eight cases had inner ear malformation. Among the nine cases, 1 cases was Mondini malformation and 1 cases was common cavity, 5 cases were single stenosis of IAC, and 2 cases were semicircular canal and vestibular malformation. 19 cases were not found abnormal by CT, and 4 cases had had suffered from mumps.
CONCLUSION
CT scan was available in diagnosis of unsudden unilateral sensorineural hearing loss, which would help us to use medical resource more rationally.
Adolescent
;
Child
;
Child, Preschool
;
Female
;
Hearing Loss, Sensorineural
;
diagnostic imaging
;
Humans
;
Male
;
Retrospective Studies
;
Tomography, X-Ray Computed
;
methods
;
Young Adult
8.The clinical application of gene chips combined with CT examination in the diagnosis of large vestibular aqueduct syndrome patients.
Feng ZHOU ; Ying LIN ; Qiong LUO ; Xiaoke CHEN ; Lifen HUANG ; Zijian LIANG ; Haitao WANG ; Feng YU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(19):1073-1075
OBJECTIVE:
To explore the feasibility and superiority of the gene chip method and temporal bone CT in diagnosis of large vestibular aqueduct syndrome.
METHOD:
One hundred and eighty-eight cases of deaf students in Guangzhou were selected,the microarray detection of the SLC26A4 gene locus was performed,and the 26 cases of students with detected SLC26A4 gene mutations received temporal bone CT imaging.
RESULT:
Among the detected 26 cases of patients with hearing loss, IVS7-2A>G homozygous mutation was found in 7 cases, 17 cases were heterozygous mutation, 2168A>G heterozygous mutation presented in three cases, including one case of IVS7-2A>G and 2168A>G compound heterozygous mutations. Temporal bone CT findings of 25 cases among the 26 patients showed bilateral large vestibular aqueduct,among which 9 cases exhibited bilateral cochlear malformations, and 1 case was normal.
CONCLUSION
Among the different SLC26A4 gene mutations, IVS7-2A>G point mutation rates the highest, followed by 2168A>G. Most of the CT examination prompted the expansion of the vestibular aqueduct. Deafness gene chip hotspot detection of SLC26A4 gene mutations can diagnose such patients before CT examination,which can be used for screening people with high risk of deafness prenatal screening. The early detection and early diagnosis can guide proper precautionary measures in advance to prevent the occurrence of prelingual deafness.
Adolescent
;
Child
;
Female
;
Hearing Loss, Sensorineural
;
diagnosis
;
diagnostic imaging
;
Humans
;
Male
;
Membrane Transport Proteins
;
genetics
;
Mutation
;
Oligonucleotide Array Sequence Analysis
;
Sulfate Transporters
;
Tomography, X-Ray Computed
;
Vestibular Aqueduct
;
abnormalities
;
diagnostic imaging
;
Vestibular Diseases
;
diagnosis
;
diagnostic imaging